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in the treatment of adult participants with a diagnosis of Diabetic Kidney Disease due to either Type 1 diabetes mellitus or Type 2...
Phase 2
Cooper City, Florida, United States and 71 other locations
This is a 2-part study evaluating the efficacy and safety of lorundrostat (an aldosterone synthase inhibitor [ASI]) for the treatment of hypertension...
Phase 2
Coconut Grove, Florida, United States and 28 other locations
The main objective of this study is to evaluate the safety, efficacy and pharmacokinetics of paricalcitol oral solution in pediatric participants of...
Phase 3
Miami, Florida, United States and 12 other locations
Primary Objectives:To evaluate the safety (compared to iron sucrose) and efficacy of ferumoxytol in pediatric CKD subjects with iron deficiency anemi...
Phase 3
Hollywood, Florida, United States and 20 other locations
This is a three-part study of MK-2060 in participants with chronic and/or end-stage kidney disease. The purpose of the study is to ...
Phase 1
Miami, Florida, United States of America and 3 other locations
ObjectivesTo assess the impact of RGLS8429 on height-adjusted total kidney volume (htTKV)To characterize the pharmacokinetic (PK) properties...
Phase 1
Coral Gables, Florida, United States of America and 27 other locations
to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...
Phase 3
Miami, Florida, United States and 321 other locations
of up to 2 REACT injections given 3 months (+30 days) apart and delivered percutaneously into biopsied and non-biopsied contralateral kidneys...
Phase 3
Miami Beach, Florida, United States and 45 other locations
tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...
Phase 2, Phase 3
Miami, Florida, United States and 236 other locations
safety, tolerability, pharmacokinetics (PK) and Pharmacodynamics (PD) of DISC-0974 in adult participants with Non-Dialysis Dependent Chronic Kidney...
Phase 1
Miami, Florida, United States and 10 other locations
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