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This is purpose of this study is to evaluate the safety, tolerability, and effect on Albuminuria of MZE829 in Adults with APOL1 Kidney Disease...
Phase 2
Bloomfield, Connecticut, United States and 71 other locations
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common genetic cause of kidney disease that caus...
Phase 2
New Haven, Connecticut, United States and 65 other locations
tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...
Phase 2, Phase 3
New Haven, Connecticut, United States and 330 other locations
The purpose of this study is to determine whether vonsetamig will safely decrease anti-HLA antibodies to allow for kidney transplantation.Vo...
Phase 1, Phase 2
New Haven, Connecticut, United States and 9 other locations
This study is open to adults with chronic kidney disease (CKD) that is at risk of getting worse. People who have taken a specific t ...
Phase 2
Smithtown, New York, United States and 160 other locations
Researchers are looking for a better way to treat people who have non-diabetic chronic kidney disease (non-diabetic CKD). The trial ...
Phase 3
New Haven, Connecticut, United States and 339 other locations
Researchers are looking for a better way to treat people who have chronic kidney disease (CKD), CKD is a condition in which the kidneys...
Phase 2
New Haven, Connecticut, United States and 156 other locations
and Tolerability of Baxdrostat in combination with Dapagliflozin on renal outcomes and cardiovascular mortality in participants with chronic kidney...
Phase 3
New Britain, Connecticut, United States and 716 other locations
The primary objective of this study is to assess the efficacy of a single dose of ravulizumab IV compared with placebo in reducing the risk of the cl...
Phase 3
Valhalla, New York, United States and 166 other locations
of serious heart-related complications or prevent the worsening of kidney function. The trial will enroll adults with body mass index 27 kg/ ...
Phase 3
Waterbury, Massachusetts, United States of America and 817 other locations
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