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Find clinical trials for Kidney Disease in Orlando, FL

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Related conditions:

Kidney Diseases
Chronic Renal Insufficiency
Chronic Kidney Failure
IGA Glomerulonephritis
Renal Cell Carcinoma
Renal Insufficiency
Carcinoma

Kidney Disease trials near Orlando, FL, USA:

Efficacy and Safety of Lorundrostat in Addition to Sodium-Glucose Cotransporter-2 Inhibitors (SGLT2i) in Subjects with Hypertension and Chronic Kidney Disease (CKD) with Albuminuria

This is a randomized, double-blind (DB), placebo controlled, crossover study with a two-period, two-sequence (2x2) design evaluating the efficacy and...

Enrolling
Chronic Kidney Disease
Drug: Lorundrostat 25mg+SGLT2i QD, Washout, Placebo+SGLT2i QD
Drug: Placebo QD + SGLT2i QD, Washout, Lorundrostat 25mg+SGLT2i QD

Phase 2

Mineralys Therapeutics

Orlando, Florida, United States and 43 other locations

To assess the impact of RGLS8429 on height-adjusted total kidney volume (htTKV)* To characterize the pharmacokinetic (PK) properties of RGLS...

Enrolling
Polycystic Kidney, Autosomal Dominant
Autosomal Dominant Polycystic Kidney Disease
Drug: Placebo
Drug: RGLS8429

Phase 1

Regulus Therapeutics

Orlando, Florida, United States and 27 other locations

to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...

Active, not recruiting
Chronic Kidney Disease With High Proteinuria
Drug: Dapagliflozin
Drug: Zibotentan/Dapagliflozin

Phase 3

AstraZeneca
AstraZeneca

Orlando, Florida, United States and 295 other locations

of up to 2 REACT injections given 3 months (+30 days) apart and delivered percutaneously into biopsied and non-biopsied contralateral kidneys...

Enrolling
Chronic Kidney Diseases
Type 2 Diabetes Mellitus
Biological: Renal Autologous Cell Therapy (REACT)
Procedure: Sham Comparator

Phase 3

Prokidney

Sanford, Florida, United States and 55 other locations

safety, tolerability, pharmacokinetics (PK) and Pharmacodynamics (PD) of DISC-0974 in adult participants with Non-Dialysis Dependent Chronic Kidney...

Enrolling
Anemia of Chronic Kidney Disease
Chronic Kidney Diseases
Drug: DISC-0974
Drug: Placebo

Phase 1

Disc Medicine

Winter Park, Florida, United States and 11 other locations

safety, tolerability and the pharmacodynamics (PD) of AZD4144 following oral administration in participants with atherosclerotic cardiovascular disease...

Enrolling
Chronic Kidney Disease
Atherosclerotic Cardiovascular Disease
Drug: AZD4144
Other: Placebo

Phase 1

AstraZeneca
AstraZeneca

Port Orange, Florida, United States and 18 other locations

The study evaluates the safety of different doses of a new medicine called NNC0519 0130. It also looks into how the medicine may improve kidney...

Enrolling
Chronic Kidney Disease
Drug: Placebo
Drug: Semaglutide

Phase 2

Novo Nordisk
Novo Nordisk

Winter Haven, Florida, United States and 101 other locations

CRP-lowering effect of quarterly and monthly subcutaneous administration of TOUR006 (also known as pacibekitug) in participants with chronic kidney...

Active, not recruiting
Kidney Insufficiency, Chronic
Chronic Kidney Diseases
Drug: TOUR006 - 25 MG
Drug: TOUR006 - 50 MG

Phase 2

Tourmaline Bio

Port Orange, Florida, United States and 48 other locations

Researchers are looking for a better way to treat people who have non-diabetic chronic kidney disease (non-diabetic CKD). The trial ...

Active, not recruiting
Non-diabetic Chronic Kidney Disease
Drug: Finerenone (BAY94-8862)
Drug: Placebo

Phase 3

Bayer
Bayer

Orlando, Florida, United States and 339 other locations

Researchers are looking for a better way to treat people who have chronic kidney disease (CKD), CKD is a condition in which the kidneys...

Enrolling
Chronic Kidney Disease
Drug: BAY3283142
Drug: Placebo

Phase 2

Bayer
Bayer

Orlando, Florida, United States and 168 other locations

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