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Find clinical trials for Kidney Disease in Orlando, FL

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Related conditions:

Kidney Diseases
Chronic Renal Insufficiency
Chronic Kidney Failure
Renal Insufficiency
IGA Glomerulonephritis
Renal Cell Carcinoma
Diabetes Mellitus

Kidney Disease trials near Orlando, FL, USA:

Efficacy and Safety of Lorundrostat Alone, and in Combination With Dapagliflozin in Subjects With Hypertension and Chronic Kidney Disease (CKD) With Albuminuria

This is a 2-part study evaluating the efficacy and safety of lorundrostat (an aldosterone synthase inhibitor [ASI]) for the treatment of hypertension...

Enrolling
Chronic Kidney Disease
Drug: Part A - Lorundrostat QD + Dapaglifozin QD
Drug: Part A - Lorundrostat QD

Phase 2

Mineralys Therapeutics

Orlando, Florida, United States and 22 other locations

to placebo in reducing the intensity of itch in advanced chronic kidney disease (CKD) patients with moderate-to-severe pruritus. Th...

Enrolling
Chronic Kidney Diseases
Pruritus
Drug: Difelikefalin 1 mg Oral Tablet
Drug: Placebo Oral Tablet

Phase 3

Cara Therapeutics
Cara Therapeutics

Orlando, Florida, United States and 82 other locations

This is a three-part study of MK-2060 in participants with chronic and/or end-stage kidney disease. The purpose of the study is to ...

Enrolling
End-Stage Renal Disease
End-Stage Kidney Disease
Biological: MK-2060
Drug: Placebo

Phase 1

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Edgewater, Florida, United States and 3 other locations

ObjectivesTo assess the impact of RGLS8429 on height-adjusted total kidney volume (htTKV)To characterize the pharmacokinetic (PK) properties...

Enrolling
Polycystic Kidney, Autosomal Dominant
Autosomal Dominant Polycystic Kidney Disease
Drug: RGLS8429
Drug: Placebo

Phase 1

Regulus Therapeutics

Orlando, Florida, United States and 27 other locations

We are doing this study to learn more about how semaglutide may help fight chronic kidney disease in people with type 2 diabetes. W...

Active, not recruiting
Chronic Kidney Disease
Diabetes Mellitus, Type 2
Drug: Semaglutide
Drug: Placebo (Semaglutide)

Phase 3

Novo Nordisk
Novo Nordisk

Orlando, Florida, United States and 32 other locations

to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...

Enrolling
Chronic Kidney Disease With High Proteinuria
Drug: Zibotentan/Dapagliflozin
Drug: Dapagliflozin

Phase 3

AstraZeneca
AstraZeneca

Orlando, Florida, United States and 305 other locations

tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...

Enrolling
Proteinuric Kidney Disease
Drug: VX-147
Drug: Placebo

Phase 2, Phase 3

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Orlando, Florida, United States and 231 other locations

safety, tolerability, pharmacokinetics (PK) and Pharmacodynamics (PD) of DISC-0974 in adult participants with Non-Dialysis Dependent Chronic Kidney...

Enrolling
Anemia of Chronic Kidney Disease
Chronic Kidney Diseases
Drug: Placebo
Drug: DISC-0974

Phase 1

Disc Medicine

Winter Park, Florida, United States and 10 other locations

evaluate the efficacy and safety of CIN-107 for the treatment of hypertension in patients with uncontrolled hypertension (uHTN) and Chronic Kidney...

Active, not recruiting
Chronic Kidney Diseases
Uncontrolled Hypertension
Drug: Placebo
Drug: CIN-107

Phase 2

AstraZeneca
AstraZeneca

Orlando, Florida, United States and 70 other locations

Researchers are looking for a better way to treat people who have non-diabetic chronic kidney disease (non-diabetic CKD). The trial ...

Active, not recruiting
Non-diabetic Chronic Kidney Disease
Drug: Finerenone (BAY94-8862)
Drug: Placebo

Phase 3

Bayer
Bayer

Orlando, Florida, United States and 312 other locations

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