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Find clinical trials for Kidney Disease in Orlando, FL

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Related conditions:

Chronic Renal Insufficiency
Kidney Diseases
Chronic Kidney Failure
IGA Glomerulonephritis
Renal Insufficiency
Renal Cell Carcinoma
Kidney Cancer

Kidney Disease trials near Orlando, FL, USA:

A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease

The purpose of this study is to evaluate the safety, tolerability, and effect on Albuminuria of MZE829 in Adults with APOL1 Kidney Disease...

Enrolling
Proteinuric Kidney Disease
Drug: MZE829

Phase 2

Maze Therapeutics

Orlando, Florida, United States and 85 other locations

This study is researching an experimental drug called ALN-ANG3 (called "study drug"). The study is focused on participants who have diabetic kidney...

Enrolling
Diabetic Kidney Disease (DKD)
Drug: Evinacumab
Drug: ALN-ANG3

Phase 2

Regeneron Pharmaceuticals
Regeneron Pharmaceuticals

Orlando, Florida, United States and 59 other locations

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common genetic cause of kidney disease that caus...

Enrolling
Autosomal Dominant Polycystic Kidney Disease
Drug: ABBV-CLS-628
Drug: Placebo

Phase 2

Calico Life Sciences
Calico Life Sciences

Sanford, Florida, United States and 92 other locations

The purpose of this study is to assess the efficacy and safety of AZD2373 in participants diagnosed with APOL1-Mediated Kidney Disease...

Active, not recruiting
APOL1-Mediated Kidney Disease
Combination Product: AZD2373-Arm 2
Device: APOL1 Genotyping Clinical Trial Assay

Phase 2

AstraZeneca
AstraZeneca

Orlando, Florida, United States and 62 other locations

baxdrostat in combination with dapagliflozin compared with baxdrostat/placebo on albuminuria, as well as safety, in participants with chronic kidney...

Active, not recruiting
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozin
Drug: Baxdrostat/Placebo

Phase 2

AstraZeneca
AstraZeneca

Port Orange, Florida, United States and 55 other locations

Powerful new drugs that can prevent or delay end stage kidney disease (ESKD) - so called sodium-glucose cotransporter-2 inhibitors ...

Enrolling
Kidney Failure, Chronic
Diabetic Nephropathies
Drug: Placebo
Drug: Sotagliflozin

Phase 3

Alessandro Doria

Orlando, Florida, United States and 18 other locations

tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...

Enrolling
Proteinuric Kidney Disease
Drug: VX-147
Drug: Placebo

Phase 2, Phase 3

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Orlando, Florida, United States and 330 other locations

and pharmacokinetics of AZD1613 following subcutaneous or intravenous administration in participants with autosomal dominant polycystic kidney...

Enrolling
Autosomal Dominant Polycystic Kidney Disease
Drug: Placebo - Part B
Drug: Placebo - Part A

Phase 1

AstraZeneca
AstraZeneca

Orlando, Florida, United States and 14 other locations

to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...

Active, not recruiting
Chronic Kidney Disease With High Proteinuria
Drug: Dapagliflozin
Drug: Zibotentan/Dapagliflozin

Phase 3

AstraZeneca
AstraZeneca

Orlando, Florida, United States and 297 other locations

This is a Phase III, randomized, double-blind, parallel-group, placebo-controlled multicenter study to investigate outcomes with elecoglipron compare...

Enrolling
Chronic Kidney Disease
Drug: Placebo
Drug: Elecoglipron

Phase 3

AstraZeneca
AstraZeneca

Orlando, Florida, United States and 711 other locations

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