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Find clinical trials for Kidney Disease in Orlando, FL

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Related conditions:

Kidney Diseases
Chronic Renal Insufficiency
Chronic Kidney Failure
Renal Insufficiency
IGA Glomerulonephritis
Renal Cell Carcinoma
Diabetes Mellitus

Kidney Disease trials near Orlando, FL, USA:

Efficacy and Safety of Lorundrostat Alone, and in Combination With Dapagliflozin in Subjects With Hypertension and Chronic Kidney Disease (CKD) With Albuminuria

This is a 2-part study evaluating the efficacy and safety of lorundrostat (an aldosterone synthase inhibitor [ASI]) for the treatment of hypertension...

Enrolling
Chronic Kidney Disease
Drug: Part A - Lorundrostat QD + Dapaglifozin QD
Drug: Part A - Lorundrostat QD

Phase 2

Mineralys Therapeutics

Orlando, Florida, United States and 28 other locations

This is a three-part study of MK-2060 in participants with chronic and/or end-stage kidney disease. The purpose of the study is to ...

Active, not recruiting
End-Stage Renal Disease
End-Stage Kidney Disease
Biological: MK-2060
Drug: Placebo

Phase 1

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Edgewater, Florida, United States and 3 other locations

We are doing this study to learn more about how semaglutide may help fight chronic kidney disease in people with type 2 diabetes. W...

Active, not recruiting
Chronic Kidney Disease
Diabetes Mellitus, Type 2
Drug: Semaglutide
Drug: Placebo (Semaglutide)

Phase 3

Novo Nordisk
Novo Nordisk

Orlando, Florida, United States and 32 other locations

ObjectivesTo assess the impact of RGLS8429 on height-adjusted total kidney volume (htTKV)To characterize the pharmacokinetic (PK) properties...

Enrolling
Polycystic Kidney, Autosomal Dominant
Autosomal Dominant Polycystic Kidney Disease
Drug: RGLS8429
Drug: Placebo

Phase 1

Regulus Therapeutics

Orlando, Florida, United States and 27 other locations

to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...

Enrolling
Chronic Kidney Disease With High Proteinuria
Drug: Zibotentan/Dapagliflozin
Drug: Dapagliflozin

Phase 3

AstraZeneca
AstraZeneca

Orlando, Florida, United States and 321 other locations

Locations recently updated

tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...

Enrolling
Proteinuric Kidney Disease
Drug: VX-147
Drug: Placebo

Phase 2, Phase 3

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Orlando, Florida, United States and 236 other locations

safety, tolerability, pharmacokinetics (PK) and Pharmacodynamics (PD) of DISC-0974 in adult participants with Non-Dialysis Dependent Chronic Kidney...

Enrolling
Anemia of Chronic Kidney Disease
Chronic Kidney Diseases
Drug: Placebo
Drug: DISC-0974

Phase 1

Disc Medicine

Winter Park, Florida, United States and 10 other locations

evaluate the efficacy and safety of CIN-107 for the treatment of hypertension in patients with uncontrolled hypertension (uHTN) and Chronic Kidney...

Active, not recruiting
Chronic Kidney Diseases
Uncontrolled Hypertension
Drug: Placebo
Drug: CIN-107

Phase 2

AstraZeneca
AstraZeneca

Orlando, Florida, United States and 70 other locations

Researchers are looking for a better way to treat people who have non-diabetic chronic kidney disease (non-diabetic CKD). The trial ...

Active, not recruiting
Non-diabetic Chronic Kidney Disease
Drug: Finerenone (BAY94-8862)
Drug: Placebo

Phase 3

Bayer
Bayer

Orlando, Florida, United States and 312 other locations

Researchers are looking for a better way to treat people with chronic kidney disease (CKD), a progressive decrease in the kidneys...

Enrolling
Chronic Kidney Disease
Type 1 Diabetes Mellitus
Other: Placebo
Drug: Finerenone

Phase 3

Bayer
Bayer

Orlando, Florida, United States and 80 other locations

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