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Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common genetic cause of kidney disease that caus...
Phase 2
Rochester, Minnesota, United States and 46 other locations
is to evaluate the effect of tolvaptan on the need for renal replacement therapy in pediatric subjects with autosomal recessive polycystic kidney...
Phase 3
Rochester, Minnesota, United States and 17 other locations
and pharmacokinetics of AZD1613 following subcutaneous or intravenous administration in participants with autosomal dominant polycystic kidney...
Phase 1
Rochester, Minnesota, United States and 10 other locations
safety, tolerability, pharmacokinetics (PK) and Pharmacodynamics (PD) of DISC-0974 in adult participants with Non-Dialysis Dependent Chronic Kidney...
Phase 1
Rochester, Minnesota, United States and 11 other locations
To evaluate the safety of tolvaptan in pediatric subjects with ARPKD
Phase 3
Rochester, Minnesota, United States and 22 other locations
This study is an open-label, multi-center study evaluating the clinical utility of Renasight in the diagnosis and management of kidney disease...
Rochester, Minnesota, United States and 30 other locations
A first-in-human study of KK8123 in adults with X-linked hypophosphatemia.
Phase 1, Phase 2
Rochester, Minnesota, United States and 8 other locations
The proposed study is designed to provide patients previously enrolled in Phase 1 and 2 studies of DCR-PHXC and their siblings (\<18 years old) long-...
Phase 3
Rochester, Minnesota, United States and 22 other locations
efficacy assessments conducted every 6 months will afford the opportunity to evaluate the clinical effects of iptacopan on long-term disease...
Phase 3
Rochester, Minnesota, United States and 146 other locations
PLD (ADPLD) or associated with autosomal dominant polycystic kidney disease (ADPKD).In the Treatment Period of the trial, participa...
Phase 2, Phase 3
Rochester, Minnesota, United States and 10 other locations
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