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Powerful new drugs that can prevent or delay end stage kidney disease (ESKD) - so called sodium-glucose cotransporter-2 inhibitors ...
Phase 3
St. Louis, Missouri, United States and 17 other locations
to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...
Phase 3
Saint Peters, Missouri, United States and 295 other locations
of up to 2 REACT injections given 3 months (+30 days) apart and delivered percutaneously into biopsied and non-biopsied contralateral kidneys...
Phase 3
SAINT LOUIS, Missouri, United States of America and 55 other locations
compared with dapagliflozin alone on patients with chronic kidney disease (CKD) and albuminuria. This study will evaluate the effec...
Phase 2
Saint Louis, Missouri, United States and 116 other locations
Researchers are looking for a better way to treat people who have non-diabetic chronic kidney disease (non-diabetic CKD). The trial ...
Phase 3
Saint Louis, Missouri, United States and 338 other locations
Researchers are looking for a better way to treat people with chronic kidney disease (CKD), a progressive decrease in the kidneys...
Phase 3
Saint Louis, Missouri, United States and 84 other locations
receptor is known to trigger injury and inflammation in the kidney and is therefore thought to play a role in CKD.Empagliflozin lowers blood...
Phase 2
Saint Louis, Missouri, United States and 188 other locations
tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...
Phase 2, Phase 3
Saint Louis, Missouri, United States and 297 other locations
The primary objective of this study is to assess the efficacy of a single dose of ravulizumab IV compared with placebo in reducing the risk of the cl...
Phase 3
Saint Louis, Missouri, United States and 195 other locations
of serious heart-related complications or prevent the worsening of kidney function. The trial will enroll adults with body mass index 27 kg/ ...
Phase 3
Saint Peters, Missouri, United States and 744 other locations
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