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Find clinical trials for Kidney Disease in Toronto, ON

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Related conditions:

Chronic Renal Insufficiency
Kidney Diseases
Chronic Kidney Failure
IGA Glomerulonephritis
Renal Insufficiency
Renal Cell Carcinoma
Kidney Cancer

Kidney Disease trials near Toronto, ON, CAN:

Goal-Directed Therapy to Reduce Kidney and Cardiovascular Risk in Diabetic Kidney Disease (GOLD-STANDARD)

safety, and implementation of an early goal-directed Cardio-Kidney-Metabolic (CKM) care strategy compared with usual care in adults with typ ...

Enrolling
Chronic Kidney Disease
Diabetic Kidney Disease (DKD)
Other: Early goal-directed Cardio-Kidney-Metabolic (CKM) care
Other: Standard care (Comparison arm)
Sunnybrook Health Sciences Centre

Toronto, Ontario, Canada

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common genetic cause of kidney disease that caus...

Enrolling
Autosomal Dominant Polycystic Kidney Disease
Drug: ABBV-CLS-628
Drug: Placebo

Phase 2

Calico Life Sciences
Calico Life Sciences

Toronto, Ontario, Canada and 92 other locations

people who have a kidney disease called autosomal dominant polycystic kidney disease (ADPKD)....

Active, not recruiting
Kidney Disease
Drug: Placebo matching GSK4771261
Drug: GSK4771261

Phase 1

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Toronto, Ontario, Canada and 22 other locations

baxdrostat in combination with dapagliflozin compared with baxdrostat/placebo on albuminuria, as well as safety, in participants with chronic kidney...

Active, not recruiting
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozin
Drug: Baxdrostat/Placebo

Phase 2

AstraZeneca
AstraZeneca

Etobicoke, Ontario, Canada and 55 other locations

Powerful new drugs that can prevent or delay end stage kidney disease (ESKD) - so called sodium-glucose cotransporter-2 inhibitors ...

Enrolling
Kidney Failure, Chronic
Diabetic Nephropathies
Drug: Placebo
Drug: Sotagliflozin

Phase 3

Alessandro Doria

Toronto, Ontario, Canada and 18 other locations

tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...

Enrolling
Proteinuric Kidney Disease
Drug: VX-147
Drug: Placebo

Phase 2, Phase 3

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Toronto, Canada and 330 other locations

with placebo in participants with atherosclerotic cardiovascular disease (ASCVD) and/or chronic kidney disease (CKD). Part...

Enrolling
Chronic Kidney Disease
Atherosclerosis Cardiovascular Disease
Drug: Orforglipron
Drug: Placebo

Phase 3

Lilly
Lilly

Brampton, Canada and 561 other locations

This study is open to children aged 2 to 17 with chronic kidney disease (CKD). The purpose of this study is to find out if a medici...

Enrolling
Chronic Kidney Disease
Drug: Placebo
Drug: Empagliflozin

Phase 3

Boehringer Ingelheim
Boehringer Ingelheim

Toronto, Ontario, Canada and 94 other locations

This is a Phase III, randomized, double-blind, parallel-group, placebo-controlled multicenter study to investigate outcomes with elecoglipron compare...

Enrolling
Chronic Kidney Disease
Drug: Placebo
Drug: Elecoglipron

Phase 3

AstraZeneca
AstraZeneca

Toronto, Ontario, Canada and 711 other locations

to healthy participants (Phase I) or participants with end-stage kidney disease receiving hemodialysis through a central venous cat...

Enrolling
Staphylococcus Aureus
Drug: AZD7760
Other: Placebo

Phase 1, Phase 2

AstraZeneca
AstraZeneca

Ridgewood, New York, United States and 43 other locations

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