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in patients with relapsed or refractory (R/R) acute myeloid leukemia (AML). The main study has completed enrollment.In Sub-studies 1 and 2...
Phase 1, Phase 2
Baltimore, Maryland, United States and 43 other locations
neutrophilia (MDS/MPN-N), also called as atypical chronic myeloid leukemia, or chronic neutrophilic leukemia. Momelotinib will be a...
Early Phase 1
Baltimore, Maryland, United States
kinase 3 (FLT3)-internal tandem duplication (ITD) (+) acute myeloid leukemia (AML) in first complete remission (CR) who have not received al...
Phase 2
Baltimore, Maryland, United States and 57 other locations
allogeneic hematopoietic stem cell transplant (HCT), versus Conventional Care in patients with Active, Relapsed or Refractory Acute Myeloid Leukemia...
Phase 3
Washington, District of Columbia, United States and 23 other locations
A phase 1/2 dose escalation / dose expansion study of Enzomenib (DSP-5336) in patients with acute leukemia....
Phase 1, Phase 2
Baltimore, Maryland, United States and 103 other locations
People with acute myeloid leukemia (AML) are usually treated with chemotherapy. Some people with AML have a changed FLT3 gene which causes l...
Phase 1, Phase 2
Baltimore, Maryland, United States and 19 other locations
This study is to find out if treating Chronic Myelomonocytic Leukemia (CMML) with a study drug (ruxolitinib) can improve outcomes of patient...
Phase 2
Baltimore, Maryland, United States and 4 other locations
in participants with previously untreated chronic lymphocytic leukemia (CLL). This study is designed to assess the contribution of sonrotocl...
Phase 2
Baltimore, Maryland, United States and 32 other locations
safety, tolerability, pharmacokinetics, pharmacodynamics, and anti-tumor activity of DR-01 in adult patients with large granular lymphocytic leukemia...
Phase 1, Phase 2
Fairfax, Virginia, United States and 36 other locations
with Azacitidine and in triple combination with Azacitidine and Venetoclax in participants with relapsed or refractory acute myeloid leukemia...
Phase 1
Fairfax, Virginia, United States and 15 other locations
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