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Find clinical trials for Leukemia in Cincinnati, OH

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Related conditions:

Acute Myeloid Leukemia
B-Cell Chronic Lymphocytic Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Myelodysplastic Syndromes
Recurrence
Myeloid Leukemia
Lymphoma

Leukemia trials near Cincinnati, OH, USA:

Adding Asciminib to Usual Treatment for Adults With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia

improve how chemotherapy works against Ph+ Acute Lymphoblastic Leukemia (ALL) and is this approach better than the usual approach for Ph+ALL...

Invitation-only
Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
CD19+ Acute Leukemia
Drug: Maintenance
Drug: Induction Phase

Phase 2

SWOG Cancer Research Network
SWOG Cancer Research Network

Cincinnati, Ohio, United States and 10 other locations

Phase 2 dose (RP2D) of revumenib in participants with acute leukemia.In Phase 2, participants will be enrolled in 4 indication-specific expa...

Enrolling
Acute Leukemia of Ambiguous Lineage
Mixed Phenotype Acute Leukemia
Drug: revumenib
Drug: cobicistat

Phase 1, Phase 2

Syndax Pharmaceuticals
Syndax Pharmaceuticals

Cincinnati, Ohio, United States and 56 other locations

Multicenter Parallel 2 Cohort Phase 2 Study of LP-168 and Obinutuzumab for Previously Treated, and T474 Gatekeeper Mutant Chronic Lymphocytic Leukemia...

Enrolling
Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: LP-168
Drug: Obinutuzumab

Phase 2

Zulfa Omer

Cincinnati, Ohio, United States

The T-RRex study evaluates the efficacy of WU-CART-007 for patients with Relapsed/Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia (T-AL...

Enrolling
T-cell Acute Lymphoblastic Leukemia
Lymphoblastic Lymphoma
Biological: WU-CART-007

Phase 2

Allotera Therapeutics

Cincinnati, Ohio, United States and 17 other locations

The aim of this study is to support development of asciminib in the pediatric population (1 to \<18 years) previously treated with one or more TKIs....

Enrolling
Myeloid Leukemia, Philadelphia Positive
Drug: Asciminib Adult formulation group
Drug: Asciminib Pediatric formulation group

Phase 1, Phase 2

Novartis
Novartis

Cincinnati, Ohio, United States and 38 other locations

4A10 in patients with relapsed or hard-to-treat acute lymphoblastic leukemia (ALL) or lymphoblastic lymphoma.4A10 is a targeted therapy desi...

Enrolling
Acute Lymphoblastic Leukemia ALL
Lymphoblastic Lymphoma
Drug: 4A10

Phase 1

Allterum Therapeutics, Inc

Cincinnati, Ohio, United States and 6 other locations

generation (2G) Tyrosine Kinase Inhibitor (TKI) nilotinib (300 mg BID), in adult patients with newly diagnosed Positive Chronic Myelogenous Leukemia...

Active, not recruiting
Philadelphia Chromosome-Positive Chronic Myeloid Leukemia
Drug: Nilotinib
Drug: Asciminib

Phase 3

Novartis
Novartis

Cincinnati, Ohio, United States of America and 118 other locations

of MDM2 for the treatment of adults with FLT3 mutated Acute Myeloid Leukemia. Participants must be relapsed/refractory (e.g., having failed ...

Active, not recruiting
Acute Myeloid Leukemia
Drug: TL-895
Drug: KRT-232

Phase 1, Phase 2

Telios Pharma

Cincinnati, Ohio, United States and 34 other locations

they have beneficial effects in treating patients with acute myeloid leukemia (AML) or acute leukemia of ambiguous lineage (ALAL) t...

Enrolling
Acute Leukemia of Ambiguous Lineage
Refractory Acute Myeloid Leukemia
Drug: Revumenib
Drug: Methotrexate

Phase 1

St. Jude Children's Research Hospital
St. Jude Children's Research Hospital

Cincinnati, Ohio, United States and 9 other locations

A multi-center, open-label, dose-finding study of five dose levels of APVO436 in combination with venetoclax and azacitidine (ven/aza) in adult patie...

Enrolling
Acute Myeloid Leukemia (AML)
Drug: Venetoclax
Drug: Azacitidine

Phase 1

Aptevo Therapeutics

Cincinnati,, Ohio, United States and 6 other locations

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