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Find clinical trials for Leukemia in Cincinnati, OH

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Related conditions:

Acute Myeloid Leukemia
B-Cell Chronic Lymphocytic Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Myeloid Leukemia
Lymphoid Leukemia
Myelodysplastic Syndromes
Lymphoma

Leukemia trials near Cincinnati, OH, USA:

Status recently updated

Adding Asciminib to Usual Treatment for Adults With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia

improve how chemotherapy works against Ph+ Acute Lymphoblastic Leukemia (ALL) and is this approach better than the usual approach for Ph+ALL...

Begins enrollment in 2 months
Invitation-only
Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
CD19+ Acute Leukemia
Drug: Maintenance
Drug: Induction Phase

Phase 2

SWOG Cancer Research Network
SWOG Cancer Research Network

Cincinnati, Ohio, United States and 1 other location

Phase 2 dose (RP2D) of revumenib in participants with acute leukemia.In Phase 2, participants will be enrolled in 3 indication-specific expa...

Enrolling
Acute Leukemia of Ambiguous Lineage
Mixed Phenotype Acute Leukemia
Drug: revumenib
Drug: cobicistat

Phase 1, Phase 2

Syndax Pharmaceuticals
Syndax Pharmaceuticals

Cincinnati, Ohio, United States and 56 other locations

Multicenter Parallel 2 Cohort Phase 2 Study of LP-168 and Obinutuzumab for Previously Treated, and T474 Gatekeeper Mutant Chronic Lymphocytic Leukemia...

Enrolling
Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: LP-168
Drug: Obinutuzumab

Phase 2

Zulfa Omer

Cincinnati, Ohio, United States

Eligible untreated patients with FLT3 acute myeloid leukemia (AML) between the ages of 18 and 70 will be randomized to receive gilteritinib ...

Active, not recruiting
Acute Myeloid Leukemia
Drug: Gilteritinib
Drug: Daunorubicin

Phase 2

PrECOG

Cincinnati, Ohio, United States and 43 other locations

chemotherapy regimen for the treatment of B-cell acute lymphoblastic leukemia. Part 1 of the study will optimize the dose of study drug (rux...

Active, not recruiting
Leukemia
Drug: Methotrexate
Drug: Thioguanine

Phase 2

Incyte
Incyte

Cincinnati, Ohio, United States and 110 other locations

The aim of this study is to support development of asciminib in the pediatric population (1 to \<18 years) previously treated with one or more TKIs....

Enrolling
Myeloid Leukemia, Philadelphia Positive
Drug: Asciminib Adult formulation group
Drug: Asciminib Pediatric formulation group

Phase 1, Phase 2

Novartis
Novartis

Cincinnati, Ohio, United States and 38 other locations

generation (2G) Tyrosine Kinase Inhibitor (TKI) nilotinib (300 mg BID), in adult patients with newly diagnosed Positive Chronic Myelogenous Leukemia...

Active, not recruiting
Philadelphia Chromosome-Positive Chronic Myeloid Leukemia
Drug: Nilotinib
Drug: Asciminib

Phase 3

Novartis
Novartis

Cincinnati, Ohio, United States of America and 119 other locations

of MDM2 for the treatment of adults with FLT3 mutated Acute Myeloid Leukemia. Participants must be relapsed/refractory (e.g., having failed ...

Active, not recruiting
Acute Myeloid Leukemia
Drug: TL-895
Drug: KRT-232

Phase 1, Phase 2

Telios Pharma

Cincinnati, Ohio, United States and 34 other locations

evaluate the safety, pharmacokinetics, pharmacodynamics, and preliminary efficacy of ZE50-0134 in relapsed and refractory chronic lymphocytic leukemia...

Enrolling
CLL (Chronic Lymphocytic Leukemia)
CLL / SLL
Drug: ZE 50-0134

Phase 1

Lomond Therapeutics Holdings, Inc.

Cincinnati, Ohio, United States and 3 other locations

they have beneficial effects in treating patients with acute myeloid leukemia (AML) or acute leukemia of ambiguous lineage (ALAL) t...

Enrolling
Acute Leukemia of Ambiguous Lineage
Refractory Acute Myeloid Leukemia
Drug: Revumenib
Drug: Methotrexate

Phase 1

St. Jude Children's Research Hospital
St. Jude Children's Research Hospital

Cincinnati, Ohio, United States and 7 other locations

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