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Find clinical trials for Leukemia in London, England

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Related conditions:

Acute Myeloid Leukemia
B-Cell Chronic Lymphocytic Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Myelodysplastic Syndromes
Recurrence
Lymphoma
Myeloid Leukemia

Leukemia trials near London, England, GBR:

Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors

this study is to evaluate the safety, tolerability, pharmacokinetics, and efficacy of ponatinib in children aged 1 to \< 18 years with advanced leukemias...

Enrolling
Accelerated Phase Chronic Myeloid Leukemia
Acute Lymphocytic Leukemia
Drug: Ponatinib

Phase 1, Phase 2

Incyte
Incyte

Sutton, United Kingdom and 24 other locations

This study is evaluating the safety and efficacy of a new BTK inhibitor, acalabrutinib, for the treatment of chronic lymphocytic leukemia (C...

Active, not recruiting
Chronic Lymphocytic Leukemia
Prolymphocytic Leukemia
Drug: Acalabrutinib

Phase 1, Phase 2

Acerta Pharma
Acerta Pharma

London, United Kingdom and 11 other locations

The goal of this clinical trial is to learn if pacritinib works better than hydroxyurea to treat advanced proliferative chronic myelomonocytic leukemia...

Enrolling
Leukemia, Myelomonocytic, Chronic
Drug: Pacritinib
Drug: Hydroxyurea

Phase 2

Theradex

London, Greater London, United Kingdom and 5 other locations

tolerability, pharmacokinetics, pharmacodynamics, and efficacy of AZD4512 in patients with relapsed/refractory B-Cell acute lymphoblastic leukemia...

Enrolling
B-cell Acute Lymphoblastic Leukemia (B-ALL)
Combination Product: AZD4512 monotherapy

Phase 1, Phase 2

AstraZeneca
AstraZeneca

Bloomsbury, United Kingdom and 26 other locations

Acute myeloid leukemia (AML) is an aggressive blood cancer, withwith few options for participants who relapse after treatment or who don't r...

Enrolling
Acute Myeloid Leukemia
Drug: Pivekimab Sunirine

Phase 1

AbbVie
AbbVie

Cambridge, Cambridgeshire, United Kingdom and 13 other locations

A phase 1/2 dose escalation / dose expansion study of Enzomenib (DSP-5336) in patients with acute leukemia....

Enrolling
Leukemia, Lymphocytic, Acute
Leukemia, Myeloid, Acute
Drug: azoles
Drug: Gilteritinib

Phase 1, Phase 2

Sumitomo Pharma
Sumitomo Pharma

London, United Kingdom and 103 other locations

Researchers are looking for a new way to treat a blood cancer called chronic myeloid leukemia (CML). Researchers want to learn if MK-4208 (T...

Enrolling
Chronic Myeloid Leukemia
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Drug: MK-4208

Phase 1, Phase 2

Terns, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

London, England, United Kingdom and 53 other locations

of the combinations of AG-120 with azacitidine and AG-221 with azacitidine versus with azacitidine alone in participants with acute myeloid leukemia...

Active, not recruiting
Leukemia, Myeloid, Acute
Drug: Azacitidine
Drug: AG-120

Phase 1, Phase 2

Celgene
Celgene

London, United Kingdom and 48 other locations

generation (2G) Tyrosine Kinase Inhibitor (TKI) nilotinib (300 mg BID), in adult patients with newly diagnosed Positive Chronic Myelogenous Leukemia...

Active, not recruiting
Philadelphia Chromosome-Positive Chronic Myeloid Leukemia
Drug: Nilotinib
Drug: Asciminib

Phase 3

Novartis
Novartis

London, United Kingdom and 118 other locations

The purpose of this study is to determine the recommended Phase 2 dose (RP2D) candidate(s) of bleximenib in combination with AML directed therapies (...

Active, not recruiting
Leukemia, Myeloid, Acute
Drug: Cytarabine
Drug: Bleximenib

Phase 1

Janssen (J&J Innovative Medicine)
Janssen (J&J Innovative Medicine)

London, United Kingdom and 33 other locations

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