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Find clinical trials for Leukemia in Los Angeles, CA

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Related conditions:

Acute Myeloid Leukemia
B-Cell Chronic Lymphocytic Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Myelodysplastic Syndromes
Myeloid Leukemia
Recurrence
Lymphoma

Leukemia trials near Los Angeles, CA, USA:

First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia

in patients with relapsed or refractory (R/R) acute myeloid leukemia (AML). The main study has completed enrollment.In Sub-studies 1 and 2...

Active, not recruiting
Acute Leukemia of Ambiguous Lineage
Mixed Phenotype Acute Leukemia
Drug: Ziftomenib
Drug: Itraconazole

Phase 1, Phase 2

Kura Oncology

Los Angeles, California, United States and 43 other locations

Locations recently updated

improve how chemotherapy works against Ph+ Acute Lymphoblastic Leukemia (ALL) and is this approach better than the usual approach for Ph+ALL...

Invitation-only
Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
CD19+ Acute Leukemia
Drug: Maintenance
Drug: Induction Phase

Phase 2

SWOG Cancer Research Network
SWOG Cancer Research Network

Orange, California, United States and 9 other locations

Phase 2 dose (RP2D) of revumenib in participants with acute leukemia.In Phase 2, participants will be enrolled in 4 indication-specific expa...

Enrolling
Acute Leukemia of Ambiguous Lineage
Mixed Phenotype Acute Leukemia
Drug: revumenib
Drug: cobicistat

Phase 1, Phase 2

Syndax Pharmaceuticals
Syndax Pharmaceuticals

Los Angeles, California, United States and 56 other locations

This study will evaluate the safety, tolerability, and efficacy of Orca-T in participants undergoing reduced intensity or non-myeloablative allogenei...

Enrolling
Mixed Phenotype Acute Leukemia
Leukemia, Myeloid, Acute
Biological: Orca-T

Phase 2

Orca Bio

Los Angeles, California, United States and 5 other locations

NMS-03597812 as single agent in Relapsed/Refractory Acute Myeloid Leukemia (R/R AML) patients who have exhausted standard treatment, includi...

Enrolling
Relapsed/Refractory Acute Myeloid Leukemia
Drug: NMS-03597812

Phase 1

Nerviano Medical Sciences

Duarte, California, United States and 6 other locations

in future studies in study participants diagnosed with acute myeloid leukemia (AML), myelodysplastic syndromes with increased blasts grade 2...

Enrolling
Leukemia, Myeloid, Acute
Chronic Myelomonocytic Leukemia
Drug: Venetoclax Oral Tablet
Drug: Tuspetinib

Phase 1, Phase 2

Aptose Biosciences

Los Angeles, California, United States and 33 other locations

Study CBX-250-001 is a Phase 1, open-label, dose-escalation study of CBX-250 in participants with relapsed/refractory AML, HR-MDS, CMML, and CML. Par...

Enrolling
AML - Acute Myeloid Leukemia
Chronic Myeloid Leukemia
Drug: CBX-250

Phase 1

Crossbow Therapeutics, Inc.

Duarte, California, United States and 10 other locations

chemotherapy in induction-eligible patients with acute myeloid leukemia.This study involves the following:* Venetoclax and azacitidine (inve...

Active, not recruiting
Acute Myeloid Leukemia
Drug: Venetoclax
Drug: Azacitidine

Phase 2

Mass General Brigham
Mass General Brigham

Duarte, California, United States and 8 other locations

tolerability, pharmacokinetics, pharmacodynamics, and efficacy of AZD4512 in patients with relapsed/refractory B-Cell acute lymphoblastic leukemia...

Enrolling
B-cell Acute Lymphoblastic Leukemia (B-ALL)
Combination Product: AZD4512 monotherapy

Phase 1, Phase 2

AstraZeneca
AstraZeneca

Duarte, California, United States and 25 other locations

Locations recently updated

This Phase 3 study in adult participants with newly diagnosed low-risk APL will evaluate the efficacy, safety, and PK of an oral capsule formulation...

Enrolling
Acute Promyelocytic Leukemia With PML-RARA
Acute Promyelocytic Leukemia
Drug: IV arsenic trioxide (ATO) + ATRA
Drug: QTX-2101 + ATRA

Phase 3

Quetzal Therapeutics

Los Angeles, California, United States and 15 other locations

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