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Find clinical trials for Leukemia in Nashville, TN

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Related conditions:

Acute Myeloid Leukemia
B-Cell Chronic Lymphocytic Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Myeloid Leukemia
Myelodysplastic Syndromes
Lymphoid Leukemia
Lymphoma

Leukemia trials near Nashville, TN, USA:

First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia

in patients with relapsed or refractory (R/R) acute myeloid leukemia (AML). The main study has completed enrollment.In Sub-studies 1 and 2...

Enrolling
Acute Leukemia of Ambiguous Lineage
Mixed Phenotype Acute Leukemia
Drug: Ziftomenib
Drug: Itraconazole

Phase 1, Phase 2

Kura Oncology

Nashville, Tennessee, United States and 55 other locations

safety and preliminary efficacy of CER-1236 in patients with relapsed/refractory (R/R), measurable residual disease (MRD) positive acute myeloid leukemia...

Enrolling
Refractory Acute Myeloid Leukemia
Acute Myeloid Leukemia
Drug: Cyclophosphamide
Drug: CER-1236

Phase 1

CERo Therapeutics Holdings, Inc.

Nashville, Tennessee, United States and 3 other locations

in treating pediatric and young adult patients with acute myeloid leukemia (AML) or acute leukemia of ambiguous lineage (ALAL) that...

Active, not recruiting
Refractory Acute Leukemia of Ambiguous Lineage
Acute Myeloid Leukemia, in Relapse
Drug: Methotrexate
Drug: Venetoclax

Phase 1

St. Jude Children's Research Hospital
St. Jude Children's Research Hospital

Nashville, Tennessee, United States and 7 other locations

This study will evaluate the safety, tolerability, and efficacy of Orca-T in participants undergoing reduced intensity or non-myeloablative allogenei...

Enrolling
Mixed Phenotype Acute Leukemia
Leukemia, Myeloid, Acute
Biological: Orca-T

Phase 2

Orca Bio

Nashville, Tennessee, United States and 4 other locations

Study CBX-250-001 is a Phase 1, open-label, dose-escalation study of CBX-250 in participants with relapsed/refractory AML, HR-MDS, CMML, and CML. Par...

Enrolling
AML - Acute Myeloid Leukemia
Chronic Myeloid Leukemia
Drug: CBX-250

Phase 1

Crossbow Therapeutics, Inc.

Nashville, Tennessee, United States and 10 other locations

Eligible untreated patients with FLT3 acute myeloid leukemia (AML) between the ages of 18 and 70 will be randomized to receive gilteritinib ...

Active, not recruiting
Acute Myeloid Leukemia
Drug: Gilteritinib
Drug: Daunorubicin

Phase 2

PrECOG

Nashville, Tennessee, United States and 43 other locations

Locations recently updated

tolerability, pharmacokinetics, pharmacodynamics, and efficacy of AZD4512 in patients with relapsed/refractory B-Cell acute lymphoblastic leukemia...

Enrolling
B-cell Acute Lymphoblastic Leukemia (B-ALL)
Combination Product: AZD4512 monotherapy

Phase 1, Phase 2

AstraZeneca
AstraZeneca

Franklin, Tennessee, United States and 25 other locations

This first-in-human study will evaluate RVU120 (SEL120), a novel small molecule CDK8/19 inhibitor, in patients with Acute Myeloid Leukemia (...

Active, not recruiting
Acute Myeloid Leukemia
High-risk Myelodysplastic Syndrome
Drug: RVU120(SEL120)

Phase 1

Ryvu Therapeutics

Nashville, Tennessee, United States and 9 other locations

This is a Phase 1/2, multicenter, open-label study to evaluate the safety and efficacy of BEAM-201 in patients with relapsed/refractory T-ALL or T-LL...

Active, not recruiting
T-Cell Lymphoblastic Leukemia/Lymphoma
Lymphoblastic Leukemia
Biological: BEAM-201

Phase 1, Phase 2

Beam Therapeutics

Nashville, Tennessee, United States and 9 other locations

A phase 1/2 dose escalation / dose expansion study of Enzomenib (DSP-5336) in patients with acute leukemia....

Enrolling
Leukemia, Lymphocytic, Acute
Leukemia, Myeloid, Acute
Drug: azoles
Drug: Gilteritinib

Phase 1, Phase 2

Sumitomo Pharma
Sumitomo Pharma

Nashville, Tennessee, United States and 103 other locations

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