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inhibitor, in patients with relapsed or refractory acute myeloid leukemia (AML) as part of Phase 1. In Phase 2, assessment of ziftomenib wil...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States and 51 other locations
in children and adolescents with newly diagnosed chronic myeloid leukemia (CML), or in children with Ph+ acute lymphoblastic leukemia...
Phase 2
Pittsburgh, Pennsylvania, United States and 173 other locations
Eligible untreated patients with FLT3 acute myeloid leukemia (AML) between the ages of 18 and 70 will be randomized to receive gilteritinib ...
Phase 2
Pittsburgh, Pennsylvania, United States and 43 other locations
with low-dose cytarabine (LDAC) improves overall survival (OS) versus LDAC and placebo, in treatment-naïve patients with acute myeloid leukemia...
Phase 3
Pittsburgh, Pennsylvania, United States and 108 other locations
This study enrolled 472 participants, aged 55 or older, with a diagnosis of de novo acute myeloid leukemia (AML) or AML secondary to prior m...
Phase 3
Pittsburgh, Pennsylvania, United States and 222 other locations
chemotherapy regimen for the treatment of B-cell acute lymphoblastic leukemia. Part 1 of the study will optimize the dose of study drug (rux...
Phase 2
Pittsburgh, Pennsylvania, United States and 110 other locations
(R/R) lymphoma* multiple myeloma* newly diagnosed acute myeloid leukemia (AML).This trial will be conducted in the outpatient setting in 2 p...
Phase 1
Pittsburgh, Pennsylvania, United States and 61 other locations
of the study is to characterize safety and tolerability of cusatuzumab in combination with various therapies used to treat acute myeloid leukemia...
Phase 1
Pittsburgh, Pennsylvania, United States and 22 other locations
This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2, for the treatment of patients with Ph+ Chronic Myeloid Leukemia...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States and 25 other locations
(CPX-351) works in treating patients with secondary acute myeloid leukemia who are younger than 60 years old. Drugs used in chemotherapy, su...
Phase 2
Pittsburgh, Pennsylvania, United States and 3 other locations
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