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Find clinical trials for Leukemia in Pittsburgh, PA

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Related conditions:

Myeloid Leukemia
Acute Myeloid Leukemia
Lymphoid Leukemia
B-Cell Chronic Lymphocytic Leukemia
Lymphoma
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Myelodysplastic Syndromes

Leukemia trials near Pittsburgh, PA, USA:

First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia

inhibitor, in patients with relapsed or refractory acute myeloid leukemia (AML) as part of Phase 1. In Phase 2, assessment of ziftomenib wil...

Enrolling
Acute Leukemia of Ambiguous Lineage
Mixed Phenotype Acute Leukemia
Drug: Ziftomenib

Phase 1, Phase 2

Kura Oncology

Pittsburgh, Pennsylvania, United States and 51 other locations

in children and adolescents with newly diagnosed chronic myeloid leukemia (CML), or in children with Ph+ acute lymphoblastic leukemia...

Active, not recruiting
Leukemia
Drug: Dasatinib

Phase 2

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Pittsburgh, Pennsylvania, United States and 173 other locations

with low-dose cytarabine (LDAC) improves overall survival (OS) versus LDAC and placebo, in treatment-naïve patients with acute myeloid leukemia...

Active, not recruiting
Acute Myeloid Leukemia (AML)
Drug: Placebo
Drug: Venetoclax

Phase 3

AbbVie
AbbVie

Pittsburgh, Pennsylvania, United States and 108 other locations

Eligible untreated patients with FLT3 acute myeloid leukemia (AML) between the ages of 18 and 70 will be randomized to receive gilteritinib ...

Active, not recruiting
Acute Myeloid Leukemia
Drug: Gilteritinib
Drug: Daunorubicin

Phase 2

PrECOG

Pittsburgh, Pennsylvania, United States and 43 other locations

chemotherapy regimen for the treatment of B-cell acute lymphoblastic leukemia. Part 1 of the study will optimize the dose of study drug (rux...

Active, not recruiting
Leukemia
Drug: Methotrexate
Drug: Thioguanine

Phase 2

Incyte
Incyte

Pittsburgh, Pennsylvania, United States and 110 other locations

This study enrolled 472 participants, aged 55 or older, with a diagnosis of de novo acute myeloid leukemia (AML) or AML secondary to prior m...

Active, not recruiting
Leukemia, Myeloid, Acute
Drug: Placebo
Drug: Oral Azacitidine

Phase 3

Celgene
Celgene

Pittsburgh, Pennsylvania, United States and 222 other locations

(R/R) lymphoma* multiple myeloma* newly diagnosed acute myeloid leukemia (AML).This trial will be conducted in the outpatient setting in 2 p...

Active, not recruiting
Acute Myeloid Leukemia
Multiple Myeloma
Drug: Dexamethasone
Drug: Venetoclax

Phase 1

Pfizer
Pfizer

Pittsburgh, Pennsylvania, United States and 61 other locations

This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2, for the treatment of patients with Ph+ Chronic Myeloid Leukemia...

Enrolling
Chronic Myeloid Leukemia
Drug: Dasatinib
Drug: Nilotinib

Phase 1, Phase 2

Kartos Therapeutics
Kartos Therapeutics

Pittsburgh, Pennsylvania, United States and 25 other locations

(CPX-351) works in treating patients with secondary acute myeloid leukemia who are younger than 60 years old. Drugs used in chemotherapy, su...

Enrolling
Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
Therapy-Related Acute Myeloid Leukemia
Drug: Liposome-encapsulated Daunorubicin-Cytarabine

Phase 2

Roswell Park Comprehensive Cancer Center
Roswell Park Comprehensive Cancer Center

Pittsburgh, Pennsylvania, United States and 3 other locations

Acute Myeloid Leukaemia (AML) is an aggressive and rare cancer of myeloid cells (a white blood cell responsible for fighting infections). Successful...

Active, not recruiting
Acute Myeloid Leukemia (AML)
Drug: Placebo
Drug: Azacitidine

Phase 3

AbbVie
AbbVie

Pittsburgh, Pennsylvania, United States and 171 other locations

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