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Find clinical trials for Leukemia in Sevilla, AN

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Related conditions:

Acute Myeloid Leukemia
Myeloid Leukemia
B-Cell Chronic Lymphocytic Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Lymphoid Leukemia
Lymphoma
Myelodysplastic Syndromes

Leukemia trials near Sevilla, AN, ESP:

First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia

in patients with relapsed or refractory (R/R) acute myeloid leukemia (AML). The main study has completed enrollment.In Sub-studies 1 and 2...

Enrolling
Acute Leukemia of Ambiguous Lineage
Mixed Phenotype Acute Leukemia
Drug: Ziftomenib
Drug: Itraconazole

Phase 1, Phase 2

Kura Oncology

Sevilla, Spain and 55 other locations

Phase 2 dose (RP2D) of revumenib in participants with acute leukemia.In Phase 2, participants will be enrolled in 3 indication-specific expa...

Enrolling
Acute Leukemia of Ambiguous Lineage
Mixed Phenotype Acute Leukemia
Drug: revumenib
Drug: cobicistat

Phase 1, Phase 2

Syndax Pharmaceuticals
Syndax Pharmaceuticals

Seville, Spain and 56 other locations

a standard of care for patients with newly diagnosed acute myeloid leukemia not eligible for intensive chemotherapy (thus not eligible for a...

Active, not recruiting
Leukemia, Myeloid, Acute
Drug: Pevonedistat
Drug: Azacitidine

Phase 3

PETHEMA Foundation

Sevilla, Spain and 61 other locations

The primary objective is to define the safety and tolerability of AB8939 in patients with AML by determining the dose-limiting toxicities, the maximu...

Enrolling
Acute Myeloid Leukemia Refractory
Myelodysplastic Syndrome Acute Myeloid Leukemia
Drug: Venetoclax
Drug: AB8939

Phase 1, Phase 2

AB Science
AB Science

Seville, Spain and 9 other locations

The purpose of this study is to determine the recommended Phase 2 dose(s) (RP2D\[s\]) of bleximenib in phase 1 Part 1 (Dose Escalation) and to determ...

Enrolling
Acute Leukemias
Acute Lymphoblastic Leukemia
Drug: Bleximenib

Phase 1, Phase 2

Janssen (J&J Innovative Medicine)
Janssen (J&J Innovative Medicine)

Seville, Spain and 98 other locations

in participants with relapsed or refractory (R/R) acute myeloid leukemia (AML) or R/R higher-risk type of myelodysplastic neoplasms (type of...

Enrolling
Leukemia, Myeloid, Acute
Myelodysplastic Neoplasms
Drug: JNJ-90189892

Phase 1

Janssen (J&J Innovative Medicine)
Janssen (J&J Innovative Medicine)

Seville, Spain and 7 other locations

care treatments for patients with relapsed/refractory acute myeloid leukemia will be examined with the following agents: FLAG-IDA, low-dose ...

Enrolling
Leukemia, Myeloid, Acute
Leukemia
Drug: Gilteritinib
Biological: Granulocyte colony-stimulating factor

Phase 1

Kura Oncology

Seville, Spain and 42 other locations

The purpose of Part 1 of this study is to compare the efficacy and safety of pirtobruitinib (LOXO-305) to ibrutinib in participants with CLL/SLL; par...

Enrolling
Leukemia, B-cell
Leukemia, Lymphocytic
Drug: Pirtobrutinib
Drug: Ibrutinib

Phase 3

Loxo Oncology
Loxo Oncology

Seville, Spain and 151 other locations

and clinical activity of SNDX-5613 in combination with intensive chemotherapy in participants with newly diagnosed acute myeloid leukemia (A...

Enrolling
Acute Myeloid Leukemias
Drug: SNDX-5613
Drug: Chemotherapy Regimen

Phase 1

Syndax Pharmaceuticals
Syndax Pharmaceuticals

Sevilla, Spain and 36 other locations

The safety run-in part of the study aims to evaluate the safety and tolerability of blinatumomab alternating with low-intensity chemotherapy. The pha...

Enrolling
Newly Diagnosed Philadelphia (Ph)-Negative B-cell Precursor Acute Lymphoblastic Leukemia (ALL)
Drug: Low-intensity chemotherapy regimen
Drug: Blinatumomab

Phase 3

Amgen
Amgen

Seville, Andalusia, Spain and 187 other locations

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