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Find clinical trials for Leukemia in St Louis, MO

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Related conditions:

Acute Myeloid Leukemia
B-Cell Chronic Lymphocytic Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Myeloid Leukemia
Myelodysplastic Syndromes
Lymphoid Leukemia
Lymphoma

Leukemia trials near St Louis, MO, USA:

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation (AUGMENT-101)

Phase 2 dose (RP2D) of revumenib in participants with acute leukemia.In Phase 2, participants will be enrolled in 4 indication-specific expa...

Enrolling
Acute Leukemia of Ambiguous Lineage
Mixed Phenotype Acute Leukemia
Drug: revumenib
Drug: cobicistat

Phase 1, Phase 2

Syndax Pharmaceuticals
Syndax Pharmaceuticals

St Louis, Missouri, United States and 56 other locations

allogeneic hematopoietic stem cell transplant (HCT), versus Conventional Care in patients with Active, Relapsed or Refractory Acute Myeloid Leukemia...

Active, not recruiting
Acute Myelogenous Leukemia
Leukemia, Acute Myeloid
Drug: Iomab-B
Drug: Conventional Care

Phase 3

Actinium Pharmaceuticals
Actinium Pharmaceuticals

Saint Louis, Missouri, United States and 23 other locations

Locations recently updated

Study CBX-250-001 is a Phase 1, open-label, dose-escalation study of CBX-250 in participants with relapsed/refractory AML, HR-MDS, CMML, and CML. Par...

Enrolling
AML - Acute Myeloid Leukemia
Chronic Myeloid Leukemia
Drug: CBX-250

Phase 1

Crossbow Therapeutics, Inc.

St Louis, Missouri, United States and 10 other locations

GDX012 is a novel cell therapy developed for the treatment of certain types of cancer, including Acute Myeloid Leukemia (AML). The main aims...

Active, not recruiting
Leukemia
Drug: GDX012
Drug: Chemotherapy Agents

Phase 1, Phase 2

Takeda
Takeda

St Louis, Missouri, United States and 10 other locations

This first-in-human study will evaluate RVU120 (SEL120), a novel small molecule CDK8/19 inhibitor, in patients with Acute Myeloid Leukemia (...

Active, not recruiting
Acute Myeloid Leukemia
High-risk Myelodysplastic Syndrome
Drug: RVU120(SEL120)

Phase 1

Ryvu Therapeutics

Saint Louis, Missouri, United States and 9 other locations

This research study is studying a research drug called AZD6738 as a possible treatment for Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia...

Active, not recruiting
Leukemia
Myelodysplastic Syndrome
Drug: AZD6738

Phase 1

Mass General Brigham
Mass General Brigham

St Louis, Missouri, United States and 3 other locations

A study of acalabrutinib plus venetoclax (AV) versus venetoclax plus obinutuzumab (VO) in previously untreated chronic lymphocytic leukemia ...

Active, not recruiting
Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Drug: Venetoclax
Drug: Obinutuzumab

Phase 3

AstraZeneca
AstraZeneca

St Louis, Missouri, United States and 37 other locations

This study will be conducted in two parts. Part 1 will be the Dose Confirmation portion to determine recommended Phase 3 dose (RPTD) of venetoclax in...

Active, not recruiting
Acute Myeloid Leukemia (AML)
Drug: Venetoclax
Drug: Azacitidine

Phase 3

AbbVie
AbbVie

Saint Louis, Missouri, United States and 160 other locations

with Azacitidine and in triple combination with Azacitidine and Venetoclax in participants with relapsed or refractory acute myeloid leukemia...

Enrolling
Acute Myeloid Leukemia
Myelodysplastic Syndrome
Drug: Azacitidine
Drug: Venetoclax

Phase 1

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

St Louis, Missouri, United States and 14 other locations

study is to compare the efficacy of sonrotoclax plus zanubrutinib versus venetoclax plus obinutuzumab in participants with chronic lymphocytic leukemia...

Active, not recruiting
CLL
Drug: Zanubrutinib
Drug: Sonrotoclax

Phase 3

BeOne Medicines

St Louis, Missouri, United States and 204 other locations

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