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Find clinical trials for Leukemia in St Louis, MO

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Related conditions:

Myeloid Leukemia
Acute Myeloid Leukemia
Lymphoid Leukemia
B-Cell Chronic Lymphocytic Leukemia
Lymphoma
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Myelodysplastic Syndromes

Leukemia trials near St Louis, MO, USA:

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation (AUGMENT-101)

Phase 2 dose (RP2D) of revumenib in participants with acute leukemia.In Phase 2, participants will be enrolled in 3 indication-specific expa...

Enrolling
Acute Leukemia of Ambiguous Lineage
Mixed Phenotype Acute Leukemia
Drug: revumenib
Drug: cobicistat

Phase 1, Phase 2

Syndax Pharmaceuticals
Syndax Pharmaceuticals

Saint Louis, Missouri, United States and 47 other locations

This study is a Phase 1, open-label, dose escalation, and cohort expansion study designed to characterize the safety, tolerability, pharmacokinetics,...

Active, not recruiting
Acute Myeloid Leukemia
Biological: WU-NK-101

Phase 1

Wugen, Inc.

Saint Louis, Missouri, United States and 8 other locations

allogeneic hematopoietic stem cell transplant (HCT), versus Conventional Care in patients with Active, Relapsed or Refractory Acute Myeloid Leukemia...

Active, not recruiting
Acute Myelogenous Leukemia
Leukemia, Acute Myeloid
Drug: Iomab-B
Drug: Conventional Care

Phase 3

Actinium Pharmaceuticals
Actinium Pharmaceuticals

Saint Louis, Missouri, United States and 23 other locations

GDX012 is a novel cell therapy developed for the treatment of certain types of cancer, including Acute Myeloid Leukemia (AML). The main aims...

Enrolling
Leukemia
Drug: GDX012
Drug: Chemotherapy Agents

Phase 1, Phase 2

Takeda
Takeda

Saint Louis, Missouri, United States and 13 other locations

chemotherapy regimen for the treatment of B-cell acute lymphoblastic leukemia. Part 1 of the study will optimize the dose of study drug (rux...

Active, not recruiting
Leukemia
Drug: Methotrexate
Drug: Thioguanine

Phase 2

Incyte
Incyte

Saint Louis, Missouri, United States and 110 other locations

This first-in-human study will evaluate RVU120 (SEL120), a novel small molecule CDK8/19 inhibitor, in patients with Acute Myeloid Leukemia (...

Active, not recruiting
Acute Myeloid Leukemia
High-risk Myelodysplastic Syndrome
Drug: RVU120(SEL120)

Phase 1

Ryvu Therapeutics

Saint Louis, Missouri, United States and 9 other locations

drug levels, drug efficacy and determine the recommended dose of BMS-986497 in participants with relapsed or refractory acute myeloid leukemia...

Enrolling
Acute Myeloid Leukemia
Myelodysplastic Syndrome
Drug: BMS-986497

Phase 1

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Saint Louis, Missouri, United States and 10 other locations

This research study is studying a research drug called AZD6738 as a possible treatment for Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia...

Enrolling
Leukemia
Myelodysplastic Syndrome
Drug: AZD6738

Phase 1

Mass General Brigham
Mass General Brigham

Saint Louis, Missouri, United States and 3 other locations

This is a Phase 1/2a, multicenter, open-label, first-in-human (FIH) study of VOR33 in participants with AML or MDS who are undergoing human leukocyte...

Enrolling
Leukemia, Myeloid, Acute
Myelodysplastic Syndromes
Drug: Mylotarg
Biological: VOR33

Phase 1, Phase 2

Vor Biopharma

Saint Louis, Missouri, United States and 13 other locations

A study of acalabrutinib plus venetoclax (AV) versus venetoclax plus obinutuzumab (VO) in previously untreated chronic lymphocytic leukemia ...

Active, not recruiting
Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Drug: Venetoclax
Drug: Obinutuzumab

Phase 3

AstraZeneca
AstraZeneca

Saint Louis, Missouri, United States and 40 other locations

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