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Phase 2 dose (RP2D) of revumenib in participants with acute leukemia.In Phase 2, participants will be enrolled in 4 indication-specific expa...
Phase 1, Phase 2
Tampa, Florida, United States and 56 other locations
This study will evaluate the safety, tolerability, and efficacy of Orca-T in participants undergoing reduced intensity or non-myeloablative allogenei...
Phase 2
Tampa, Florida, United States and 4 other locations
Study CBX-250-001 is a Phase 1, open-label, dose-escalation study of CBX-250 in participants with relapsed/refractory AML, HR-MDS, CMML, and CML. Par...
Phase 1
Tampa, Florida, United States and 10 other locations
The goal of this clinical trial is to learn if pacritinib works better than hydroxyurea to treat advanced proliferative chronic myelomonocytic leukemia...
Phase 2
Tampa, Florida, United States and 3 other locations
This is an open-label, multicenter, Phase 1b/2 study to determine the safety and tolerability of IMGN632 and assess the antileukemia activity of IMGN...
Phase 1, Phase 2
Tampa, Florida, United States and 28 other locations
This study is to find out if treating Chronic Myelomonocytic Leukemia (CMML) with a study drug (ruxolitinib) can improve outcomes of patient...
Phase 2
Tampa, Florida, United States and 4 other locations
123 (CD123) in patients with relapsed/refractory acute myeloid leukemia (AML). The purpose of this study is to evaluate the safety and clini...
Phase 1
Tampa, Florida, United States and 7 other locations
participants with previously treated chronic phase - chronic myeloid leukemia (CP-CML).The study has two parts: Part 1 of the trial (Dose Es...
Phase 1, Phase 2
St. Petersburg, Florida, United States and 53 other locations
The purpose of the study is to evaluate the safety and tolerability of the study drug, calaspargase pegol, when given with multi-agent chemotherapy.
Phase 1
Tampa, Florida, United States
This Phase 1, multicenter, open-label, dose escalation and dose optimization study is designed to assess the safety, tolerability, pharmacokinetics (...
Phase 1
Tampa, Florida, United States and 8 other locations
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