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Inhibitor( TKI) , to recurrent, advanced, or metastatic small cell lung cancer (SCLC) patients , Non-Small Cell Lung (NSCL...
Phase 2
Birmingham, Alabama, United States and 6 other locations
The purpose of this study is to assess the objective response rate (ORR) of immunotherapy-based combination therapy and to assess the safety and tole...
Phase 2
Birmingham, Alabama, United States and 52 other locations
This study will evaluate two study drugs called ubamatamab and marlotamig, to see if they can help treat advanced or metastatic Non-Small Cell Lung...
Phase 2
Birmingham, Alabama, United States and 16 other locations
in combination with immune checkpoint inhibitor (ICI) atezolizumab with or without carboplatin in participants with extensive stage-small cell lung...
Phase 1, Phase 2
Birmingham, Alabama, United States and 58 other locations
The main aim of this study is to:* evaluate safety and efficacy (per Response Evaluation Criteria in Solid Tumors version 1.1 \[RECIST 1.1\] by inves...
Phase 2
Birmingham, Alabama, United States and 80 other locations
Small cell lung cancer (SCLC) is characterized by aggressive and rapid growth and a tendency to develop early spread to distant sit...
Phase 3
Birmingham, Alabama, United States and 71 other locations
agent and in combination with pembrolizumab and BBO-10203 in subjects with locally advanced and unresectable or metastatic non-small cell lung...
Phase 1
Birmingham, Alabama, United States and 37 other locations
metastatic pancreatic ductal adenocarcinoma (PDAC), non-small cell lung cancer (NSCLC), HR+/HER2- ductal and lobular breast cancer...
Phase 1
Birmingham, Alabama, United States and 28 other locations
followed by durvalumab ± tremelimumab maintenance therapy versus EP alone as first-line treatment in patients with extensive-stage small-cell lung...
Phase 3
Birmingham, Alabama, United States and 206 other locations
and antitumor activity of silevertinib (BDTX-1535). The study population comprises adults with either advanced/metastatic non-small cell lung...
Phase 1, Phase 2
Birmingham, Alabama, United States and 28 other locations
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