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Inhibitor( TKI) , to recurrent, advanced, or metastatic small cell lung cancer (SCLC) patients , Non-Small Cell Lung (NSCL...
Phase 2
Birmingham, Alabama, United States and 6 other locations
The purpose of this study is to assess the objective response rate (ORR) of immunotherapy-based combination therapy and to assess the safety and tole...
Phase 2
Birmingham, Alabama, United States and 50 other locations
in combination with immune checkpoint inhibitor (ICI) atezolizumab with or without carboplatin in participants with extensive stage-small cell lung...
Phase 1, Phase 2
Birmingham, Alabama, United States and 58 other locations
This study is being done to determine the efficacy and safety of cofetuzumab pelidotin in the PTK7-expressing, recurrent non-small cell lung ...
Phase 1
Birmingham, Alabama, United States and 25 other locations
The main aim of this study is to:* evaluate safety and efficacy (per Response Evaluation Criteria in Solid Tumors version 1.1 \[RECIST 1.1\]...
Phase 2
Birmingham, Alabama, United States and 80 other locations
agent and in combination with pembrolizumab and BBO-10203 in subjects with locally advanced and unresectable or metastatic non-small cell lung...
Phase 1
Birmingham, Alabama, United States and 34 other locations
and antitumor activity of silevertinib (BDTX-1535). The study population comprises adults with either advanced/metastatic non-small cell lung...
Phase 1, Phase 2
Birmingham, Alabama, United States and 28 other locations
metastatic pancreatic ductal adenocarcinoma (PDAC), non-small cell lung cancer (NSCLC), HR+/HER2- ductal and lobular breast cancer...
Phase 1
Birmingham, Alabama, United States and 29 other locations
This study will evaluate REGN5093 for the treatment of Non-Small Cell Lung Cancer (NSCLC) with MET alteration. The main purpose of ...
Phase 1, Phase 2
Birmingham, Alabama, United States and 39 other locations
followed by durvalumab ± tremelimumab maintenance therapy versus EP alone as first-line treatment in patients with extensive-stage small-cell lung...
Phase 3
Birmingham, Alabama, United States and 206 other locations
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