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a prospective, open-label, multi-cohort, non-randomized, multicenter phase 2 study evaluating LN-145 in patients with metastatic non-small-cell lung...
Phase 2
Cincinnati, Ohio, United States and 43 other locations
The purpose of this study is to assess the objective response rate (ORR) of immunotherapy-based combination therapy and to assess the safety and tole...
Phase 2
Kettering, Ohio, United States and 23 other locations
the efficacy and safety of an infusion of IOV-4001 in adult participants with unresectable or metastatic melanoma or advanced non-small-cell lung...
Phase 1, Phase 2
Cincinnati, Ohio, United States and 7 other locations
The main aim of this study is to:evaluate safety and efficacy (per Response Evaluation Criteria in Solid Tumors version 1.1 [RECIST 1.1] by investiga...
Phase 2
Cincinnati, Ohio, United States of America and 79 other locations
untreated for advanced or metastatic, PD-L1 positive non-small cell lung cancer (NSCLC). The primary objective is to evaluate the p...
Phase 2
Edgewood, Kentucky, United States and 23 other locations
The goal of this platform clinical trial is to test how well novel treatment combinations work in participants with lung cancer. Su ...
Phase 2
Cincinnati, Ohio, United States and 65 other locations
NSCLC comprises of approximately 84 percent (%) of all lung cancers and is often diagnosed at advanced stage due to poor prognosis....
Phase 2
Cincinnati, Ohio, United States and 57 other locations
A study to assess the Effects of MEDI4736 (Durvalumab) in Patients With Locally Advanced or Metastatic Non Small Cell Lung Cancer i...
Phase 2
Blue Ash, Ohio, United States and 137 other locations
survival compared with carboplatin, etoposide, and nivolumab alone in newly diagnosed participants with extensive-stage small cell lung cancer...
Phase 2
Cincinnati, Ohio, United States and 42 other locations
PUMA-ALI-4201 is a Phase 2 study evaluating alisertib monotherapy in patients with pathologically-confirmed small cell lung cancer ...
Phase 2
Cincinnati, Ohio, United States and 18 other locations
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