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Find clinical trials for Lung Cancer in Columbus, OH

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Related conditions:

Non-Small-Cell Lung Carcinoma
Cancer
Carcinoma
Small Cell Lung Carcinoma
Squamous Cell Carcinoma of Head and Neck
Colorectal Cancer
Triple Negative Breast Cancer

Lung Cancer trials near Columbus, OH, USA:

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

a prospective, open-label, multi-cohort, non-randomized, multicenter phase 2 study evaluating LN-145 in patients with metastatic non-small-cell lung...

Enrolling
Metastatic Non Small Cell Lung Cancer
Biological: LN-145

Phase 2

Iovance Biotherapeutics

Columbus, Ohio, United States and 43 other locations

Study Comparing the Combination Domvanalimab and Zimberelimab With Pembrolizumab in Untreated Locally Advanced or Metastatic PD-L1-High Non-Small Cell Lung Cancer (ARC-10)

This is a phase 3 study to evaluate zimberelimab (AB122) combined with domvanalimab (AB154) compared to pembrolizumab in front-line, PD-L1-high, loca...

Active, not recruiting
Squamous Non Small Cell Lung Cancer
Nonsquamous Non Small Cell Lung Cancer
Drug: Carboplatin
Drug: Paclitaxel

Phase 3

Arcus Biosciences
Arcus Biosciences

Columbus, Ohio, United States and 170 other locations

Status recently updated

Assessing an Oral EGFR Inhibitor, Sunvozertinib in Patients Who Have Advanced Non-small Cell Lung Cancer With EGFR or HER2 Mutation (WU-KONG1)

type of side effects may occur with the drug treatment. It will also measure the levels of drug in the body and preliminarily assess its anti-cancer...

Enrolling
Active, not recruiting
Non-Small Cell Lung Cancer
Drug: Sunvozertinib

Phase 1, Phase 2

Dizal Pharma

Columbus, Ohio, United States and 123 other locations

An Open-label Study of Encorafenib + Binimetinib in Patients With BRAFV600-mutant Non-small Cell Lung Cancer

in patients with BRAFV600E-mutant metastatic non-small cell lung cancer (NSCLC). Patients who are either treatment-naïve, OR who ha...

Active, not recruiting
Non-small Cell Lung Cancer
Drug: encorafenib
Drug: binimetinib

Phase 2

Pfizer
Pfizer

Columbus, Ohio, United States and 157 other locations

An Efficacy and Safety Study of Cofetuzumab Pelidotin in Participants With PTK7-Expressing, Recurrent Non-Small Cell Lung Cancer

This study is being done to determine the efficacy and safety of cofetuzumab pelidotin in the PTK7-expressing, recurrent non-small cell lung ...

Active, not recruiting
Non-small Cell Lung Cancer (NSCLC)
Cancer
Drug: Cofetuzumab Pelidotin

Phase 1

AbbVie
AbbVie

Columbus, Ohio, United States and 25 other locations

Nivolumab and Temozolomide in Treating Patients With Recurrent or Refractory Small-Cell Lung Cancer or Advanced Neuroendocrine Cancer

This phase II trial studies how well nivolumab and temozolomide work in treating patients with small-cell lung cancer that has come...

Active, not recruiting
Lung Cancer Stage IV
Small-cell Lung Cancer
Biological: Nivolumab
Drug: Temozolomide

Phase 2

Dwight Owen

Columbus, Ohio, United States and 1 other location

A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer (ALISCA-Lung1)

PUMA-ALI-4201 is a Phase 2 study evaluating alisertib monotherapy in patients with pathologically-confirmed small cell lung cancer ...

Enrolling
Small Cell Lung Cancer
Drug: Alisertib

Phase 2

Puma Biotechnology
Puma Biotechnology

Columbus, Ohio, United States and 18 other locations

Temozolomide and Atezolizumab as Second or Third Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer

This phase II trial studies the effects of temozolomide and atezolizumab as second or third line treatment for patients with small cell lung ...

Enrolling
Stage IVA Lung Cancer AJCC v8
Recurrent Lung Small Cell Carcinoma
Drug: Temozolomide
Biological: Atezolizumab

Phase 2

Dwight Owen

Columbus, Ohio, United States and 4 other locations

Locations recently updated

Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements (DURABLE)

This study will consist of a Phase 1b and Phase 2 portion. The Phase 1b portion will enroll first followed by the Phase 2 portion. Each cycle of trea...

Enrolling
Lung Cancer
Brain Metastases
Drug: Alectinib
Radiation: Stereotactic Radiosurgery

Phase 1, Phase 2

Joshua Palmer

Columbus, Ohio, United States and 1 other location

Study of Covalent Menin Inhibitor BMF-219 in Adult Patients With KRAS Driven Non-Small Cell Lung Cancer, Pancreatic Cancer, and Colorectal Cancer

A Phase 1/1b dose finding study to determine the OBD(s) and RP2D(s) of BMF-219, a covalent menin inhibitor small molecule, in subjects with KRAS muta...

Enrolling
Stage III Non-small Cell Lung Cancer
Stage III Pancreatic Cancer
Drug: BMF-219

Phase 1

Biomea Fusion

Columbus, Ohio, United States and 22 other locations

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