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The study treatment will consist of a platinum drug (carboplatin or cisplatin per investigator's choice) plus etoposide plus durvalumab plus monalizu...
Phase 2
Indianapolis, Indiana, United States and 3 other locations
combination, lurbinectedin with osimertinib, against a rare type of cancer known as transformed small cell lung cancer (SC...
Phase 1, Phase 2
Indianapolis, Indiana, United States
This phase II trial studies the effects of temozolomide and atezolizumab as second or third line treatment for patients with small cell lung ...
Phase 2
Indianapolis, Indiana, United States and 4 other locations
combination with pembrolizumab in participants with non-small cell lung cancer (NSCLC).Each treatment cycle lasts 21 days. Particip...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 12 other locations
PUMA-ALI-4201 is a Phase 2 study evaluating alisertib monotherapy in patients with pathologically-confirmed small cell lung cancer ...
Phase 2
Indianapolis, Indiana, United States and 29 other locations
This is a Phase III, Randomized, Double-blind, Placebo-controlled, Multi-center, International Study of Durvalumab or Durvalumab and Tremelimumab as...
Phase 3
Muncie, Indiana, United States and 182 other locations
KRAS G12C inhibitors (sotorasib or adagrasib) in participants with KRAS G12C-positive (KRAS G12C +) advanced or metastatic non-small cell lung...
Phase 3
Muncie, Indiana, United States and 255 other locations
of previously-untreated patients with extensive stage small cell lung cancer. Patients will receive initial chemo-immunotherapy fol...
Phase 2
Indianapolis, Indiana, United States and 4 other locations
The main objective is to compare the efficacy of tarlatamab with standard of care (SOC) on prolonging overall survival (OS).
Phase 3
Indianapolis, Indiana, United States and 224 other locations
and antitumor activity of silevertinib (BDTX-1535). The study population comprises adults with either advanced/metastatic non-small cell lung...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 43 other locations
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