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Find clinical trials for Lung Cancer in Indianapolis, IN

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Related conditions:

Non-Small-Cell Lung Carcinoma
Cancer
Carcinoma
Small Cell Lung Carcinoma
Squamous Cell Carcinoma of Head and Neck
Colorectal Cancer
Triple Negative Breast Cancer

Lung Cancer trials near Indianapolis, IN, USA:

MOnaliZumab in Combination With durvAlumab (MEDI4736) Plus Platinum-based chemotheRapy for First-line Treatment of Extensive Stage Small Cell Lung Cancer (MOZART)

The study treatment will consist of a platinum drug (carboplatin or cisplatin per investigator's choice) plus etoposide plus durvalumab plus monalizu...

Enrolling
Small Cell Lung Cancer
Extensive Stage Small Cell Lung Cancer
Drug: Etoposide
Drug: Carboplatin or Cisplatin

Phase 2

Hirva Mamdani

Indianapolis, Indiana, United States and 3 other locations

untreated for advanced or metastatic, PD-L1 positive non-small cell lung cancer (NSCLC). The primary objective is to evaluate the p...

Enrolling
Non-small Cell Lung Cancer
Drug: Pembrolizumab (MK-3475) 200 mg
Device: NovoTTF-200T

Phase 2

NovoCure
NovoCure

Indianapolis, Indiana, United States and 23 other locations

This is a Phase III, Randomized, Double-blind, Placebo-controlled, Multi-center, International Study of Durvalumab or Durvalumab and Tremelimumab as...

Active, not recruiting
Small Cell Lung Cancer
Drug: Durvalumab
Other: Placebo

Phase 3

AstraZeneca
AstraZeneca

Muncie, Indiana, United States and 181 other locations

The main objective is to compare the efficacy of tarlatamab with standard of care (SOC) on prolonging overall survival (OS).

Enrolling
Small Cell Lung Cancer (SCLC)
Drug: Topotecan
Drug: Amrubicin

Phase 3

Amgen
Amgen

Indianapolis, Indiana, United States and 219 other locations

combination with pembrolizumab in participants with non-small cell lung cancer (NSCLC).Each treatment cycle lasts 21 days. Particip...

Enrolling
Lung Cancer Metastatic
Lung Cancer Stage IV
Drug: SLC-391
Biological: pembrolizumab

Phase 1, Phase 2

SignalChem Lifesciences

Indianapolis, Indiana, United States and 12 other locations

This phase II trial studies the effects of temozolomide and atezolizumab as second or third line treatment for patients with small cell lung ...

Enrolling
Stage IVA Lung Cancer AJCC v8
Recurrent Lung Small Cell Carcinoma
Drug: Temozolomide
Biological: Atezolizumab

Phase 2

Dwight Owen

Indianapolis, Indiana, United States and 4 other locations

This Phase 3 study will evaluate the efficacy of the investigational agent MRTX849 (adagrasib) versus docetaxel in patients who have been previously...

Active, not recruiting
Advanced Non Small Cell Lung Cancer
Metastatic Non Small Cell Lung Cancer
Drug: Docetaxel
Drug: MRTX849

Phase 3

Mirati Therapeutics
Mirati Therapeutics

Indianapolis, Indiana, United States and 227 other locations

This is an open-label Phase I/II study, with a dose escalation part (Phase I) and a single-arm part (Phase II), in patients with recurrent SCLC who p...

Active, not recruiting
Lung Cancer
SCLC
Drug: Nivolumab
Drug: Plinabulin

Phase 1, Phase 2

Salma Sabbour

Indianapolis, Indiana, United States and 7 other locations

The study is a prospective, randomized controlled phase III trial aimed to test the efficacy and safety of TTFields, using the NovoTTF-200T device, c...

Active, not recruiting
Nonsmall Cell Lung Cancer
NSCLC
Drug: Immune checkpoint inhibitors or docetaxel
Device: NovoTTF-200T

Phase 3

NovoCure
NovoCure

Indianapolis, Indiana, United States and 123 other locations

This is an open label, multi-institutional, single arm study with a dose escalation phase Ib cohort, followed by a phase II cohort of pembrolizumab a...

Active, not recruiting
Non-Small Cell Lung Cancer
Drug: MK-3475
Drug: Imprime PGG

Phase 1, Phase 2

Lawrence Feldman, MD

Indianapolis, Indiana, United States and 4 other locations

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