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This study has 2 cohorts: MOZART-ES cohort (for extensive-stage SCLC) and MOZART-LS cohort (for limited-stage SCLC).MOZART-ES cohort: Study treatment...
Phase 2
Indianapolis, Indiana, United States and 3 other locations
combination) vs durvalumab in limited-stage (LS)-small-cell lung cancer (SCLC) participants.The main goals of this study are to:* E...
Phase 2
Indianapolis, Indiana, United States and 33 other locations
combination, lurbinectedin with osimertinib, against a rare type of cancer known as transformed small cell lung cancer (SC...
Phase 1, Phase 2
Indianapolis, Indiana, United States
Small cell lung cancer (SCLC) is characterized by aggressive and rapid growth and a tendency to develop early spread to distant sit...
Phase 3
Indianapolis, Indiana, United States and 62 other locations
This is a Phase III, Randomized, Double-blind, Placebo-controlled, Multi-center, International Study of Durvalumab or Durvalumab and Tremelimumab as...
Phase 3
Muncie, Indiana, United States and 182 other locations
The main objective is to compare the efficacy of tarlatamab with standard of care (SOC) on prolonging overall survival (OS).
Phase 3
Indianapolis, Indiana, United States and 224 other locations
This phase II trial studies the effects of temozolomide and atezolizumab as second or third line treatment for patients with small cell lung ...
Phase 2
Indianapolis, Indiana, United States and 4 other locations
PUMA-ALI-4201 is a Phase 2 study evaluating alisertib monotherapy in patients with pathologically-confirmed small cell lung cancer ...
Phase 2
Indianapolis, Indiana, United States and 29 other locations
The primary objective of this study is to compare the efficacy of tarlatamab plus durvalumab with durvalumab alone on prolonging overall survival (OS...
Phase 3
Indianapolis, Indiana, United States and 223 other locations
followed by durvalumab ± tremelimumab maintenance therapy versus EP alone as first-line treatment in patients with extensive-stage small-cell lung...
Phase 3
Muncie, Indiana, United States and 206 other locations
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