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untreated for advanced or metastatic, PD-L1 positive non-small cell lung cancer (NSCLC). The primary objective is to evaluate the p...
Phase 2
Indianapolis, Indiana, United States and 23 other locations
This is a Phase III, Randomized, Double-blind, Placebo-controlled, Multi-center, International Study of Durvalumab or Durvalumab and Tremelimumab as...
Phase 3
Muncie, Indiana, United States and 181 other locations
The main objective is to compare the efficacy of tarlatamab with standard of care (SOC) on prolonging overall survival (OS).
Phase 3
Indianapolis, Indiana, United States and 218 other locations
combination with pembrolizumab in participants with non-small cell lung cancer (NSCLC).Each treatment cycle lasts 21 days. Particip...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 12 other locations
This phase II trial studies the effects of temozolomide and atezolizumab as second or third line treatment for patients with small cell lung ...
Phase 2
Indianapolis, Indiana, United States and 4 other locations
This Phase 3 study will evaluate the efficacy of the investigational agent MRTX849 (adagrasib) versus docetaxel in patients who have been previously...
Phase 3
Indianapolis, Indiana, United States and 227 other locations
This is an open label, multi-institutional, single arm study with a dose escalation phase Ib cohort, followed by a phase II cohort of pembrolizumab a...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 4 other locations
The study is a prospective, randomized controlled phase III trial aimed to test the efficacy and safety of TTFields, using the NovoTTF-200T device, c...
Phase 3
Indianapolis, Indiana, United States and 123 other locations
This is an open-label Phase I/II study, with a dose escalation part (Phase I) and a single-arm part (Phase II), in patients with recurrent SCLC who p...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 7 other locations
of previously-untreated patients with extensive stage small cell lung cancer. Patients will receive initial chemo-immunotherapy fol...
Phase 2
Indianapolis, Indiana, United States and 4 other locations
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