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The study treatment will consist of a platinum drug (carboplatin or cisplatin per investigator's choice) plus etoposide plus durvalumab plus monalizu...
Phase 2
Indianapolis, Indiana, United States and 3 other locations
This is a multicenter, randomized, open-label study of Tumor Treating Fields (TTFields) at 150 kHz to the thorax using the NovoTTF-200T Syst ...
Phase 2
Indianapolis, Indiana, United States and 23 other locations
combination with pembrolizumab in participants with non-small cell lung cancer (NSCLC).Each treatment cycle lasts 21 days. Particip...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 12 other locations
The primary objective of this study is to compare the efficacy of tarlatamab plus durvalumab with durvalumab alone on prolonging overall survival (OS...
Phase 3
Indianapolis, Indiana, United States and 70 other locations
This phase II trial studies the effects of temozolomide and atezolizumab as second or third line treatment for patients with small cell lung ...
Phase 2
Indianapolis, Indiana, United States and 4 other locations
This is a Phase III, Randomized, Double-blind, Placebo-controlled, Multi-center, International Study of Durvalumab or Durvalumab and Tremelimumab as...
Phase 3
Muncie, Indiana, United States and 182 other locations
This open-label, non-randomized Phase II trial is designed to assess the safety and tolerability of GT103 in combination with pembrolizumab in adult...
Phase 2
Indianapolis, Indiana, United States and 5 other locations
The main objective is to compare the efficacy of tarlatamab with standard of care (SOC) on prolonging overall survival (OS).
Phase 3
Indianapolis, Indiana, United States and 222 other locations
of previously-untreated patients with extensive stage small cell lung cancer. Patients will receive initial chemo-immunotherapy fol...
Phase 2
Indianapolis, Indiana, United States and 4 other locations
This is an open-label Phase I/II study, with a dose escalation part (Phase I) and a single-arm part (Phase II), in patients with recurrent SCLC who p...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 7 other locations
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