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Find clinical trials for Lung Cancer in Indianapolis, IN

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Related conditions:

Non-Small-Cell Lung Carcinoma
Small Cell Lung Carcinoma
Cancer
Colorectal Cancer
Neoplasm Metastasis
Breast Cancer
Squamous Cell Carcinoma of Head and Neck

Lung Cancer trials near Indianapolis, IN, USA:

MOnaliZumab in Combination With durvAlumab (MEDI4736) for tRreatmenT of Small Cell Lung Cancer (MOZART)

This study has 2 cohorts: MOZART-ES cohort (for extensive-stage SCLC) and MOZART-LS cohort (for limited-stage SCLC).MOZART-ES cohort: Study treatment...

Enrolling
Small Cell Lung Cancer
Limited Stage Small-Cell Lung Cancer
Drug: Monalizumab
Drug: Etoposide

Phase 2

Hirva Mamdani

Indianapolis, Indiana, United States and 3 other locations

combination) vs durvalumab in limited-stage (LS)-small-cell lung cancer (SCLC) participants.The main goals of this study are to:* E...

Enrolling
Limited Stage Small Cell Lung Cancer
Drug: Durvalumab
Drug: BMS-986489

Phase 2

SCRI Development Innovations

Indianapolis, Indiana, United States and 33 other locations

combination, lurbinectedin with osimertinib, against a rare type of cancer known as transformed small cell lung cancer (SC...

Enrolling
Small Cell Lung Cancer ( SCLC )
Transformed Small Cell Lung Cancer
Drug: Osimertinib
Drug: Lurbinectedin

Phase 1, Phase 2

Misty Shields

Indianapolis, Indiana, United States

Locations recently updated

Small cell lung cancer (SCLC) is characterized by aggressive and rapid growth and a tendency to develop early spread to distant sit...

Enrolling
Small Cell Lung Cancer
Drug: Topotecan
Drug: Lurbinectedin

Phase 3

AbbVie
AbbVie

Indianapolis, Indiana, United States and 62 other locations

This is a Phase III, Randomized, Double-blind, Placebo-controlled, Multi-center, International Study of Durvalumab or Durvalumab and Tremelimumab as...

Active, not recruiting
Small Cell Lung Cancer
Drug: Durvalumab
Other: Placebo

Phase 3

AstraZeneca
AstraZeneca

Muncie, Indiana, United States and 182 other locations

The main objective is to compare the efficacy of tarlatamab with standard of care (SOC) on prolonging overall survival (OS).

Active, not recruiting
Small Cell Lung Cancer (SCLC)
Drug: Topotecan
Drug: Amrubicin

Phase 3

Amgen
Amgen

Indianapolis, Indiana, United States and 224 other locations

This phase II trial studies the effects of temozolomide and atezolizumab as second or third line treatment for patients with small cell lung ...

Enrolling
Stage IVA Lung Cancer AJCC v8
Recurrent Lung Small Cell Carcinoma
Drug: Temozolomide
Biological: Atezolizumab

Phase 2

Dwight Owen

Indianapolis, Indiana, United States and 4 other locations

PUMA-ALI-4201 is a Phase 2 study evaluating alisertib monotherapy in patients with pathologically-confirmed small cell lung cancer ...

Enrolling
Small Cell Lung Cancer
Drug: Alisertib

Phase 2

Puma Biotechnology
Puma Biotechnology

Indianapolis, Indiana, United States and 29 other locations

The primary objective of this study is to compare the efficacy of tarlatamab plus durvalumab with durvalumab alone on prolonging overall survival (OS...

Active, not recruiting
Small-Cell Lung Cancer
Extensive-Stage Small-Cell Lung Cancer
Drug: Tarlatamab
Drug: Durvalumab

Phase 3

Amgen
Amgen

Indianapolis, Indiana, United States and 223 other locations

followed by durvalumab ± tremelimumab maintenance therapy versus EP alone as first-line treatment in patients with extensive-stage small-cell lung...

Active, not recruiting
Small Cell Lung Carcinoma Extensive Disease
Drug: Carboplatin
Drug: Tremelimumab

Phase 3

AstraZeneca
AstraZeneca

Muncie, Indiana, United States and 206 other locations

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