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Find clinical trials for Lymphoma in Durham, NC

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Related conditions:

Non-Hodgkin Lymphoma
B-Cell Lymphoma
Diffuse Large B-Cell Lymphoma
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Follicular Lymphoma
B-Cell Chronic Lymphocytic Leukemia
Recurrence

Lymphoma trials near Durham, NC, USA:

Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

in participants with relapsed/refractory (R/R) peripheral T-cell lymphoma not otherwise specified (PTCL-NOS), follicular helper T-cell lymphomas...

Enrolling
Lymphoma, T-Cell
Nodal Peripheral T-Cell Lymphoma With TFH Phenotype
Drug: Pralatrexate
Drug: Belinostat

Phase 3

Corvus Pharmaceuticals
Corvus Pharmaceuticals

Chapel Hill, North Carolina, United States and 33 other locations

The purpose of this study is to test whether giving acalabrutinib is safe and effective in controlling relapsed central nervous system (CNS) lymphoma...

Active, not recruiting
Central Nervous System Lymphoma
Drug: Acalabrutinib

Phase 2

UNC Lineberger Comprehensive Cancer Center
UNC Lineberger Comprehensive Cancer Center

Chapel Hill, North Carolina, United States of America and 2 other locations

DS-3201b is an experimental drug that is being investigated in clinical research.Adults with non-Hodgkin lymphoma (NHL) may be able to join ...

Active, not recruiting
Lymphoma, Malignant
Non-hodgkin Lymphoma
Drug: DS-3201b

Phase 1

Daiichi Sankyo
Daiichi Sankyo

Durham, North Carolina, United States and 20 other locations

and ibrutinib in patients with previously treated mantle cell lymphoma to evaluate the efficacy of this combination, with the primary object...

Active, not recruiting
B Cell Lymphoma
Mantle Cell Lymphoma
Drug: Ibrutinib
Drug: Palbociclib

Phase 2

Alliance Foundation Trials

Chapel Hill, North Carolina, United States and 8 other locations

This study will characterize the safety and clinical benefit of valemetostat tosylate in participants with relapsed/refractory peripheral T-cell lymphoma...

Active, not recruiting
Relapsed/Refractory Peripheral T-Cell Lymphoma
Adult T Cell Leukemia/Lymphoma
Drug: Valemetostat Tosylate

Phase 2

Daiichi Sankyo
Daiichi Sankyo

Durham, North Carolina, United States and 59 other locations

Locations recently updated

compared with rituximab and temozolomide (R-TMZ) combination therapy in participants with Relapsed/Refractory Primary Central Nervous System Lymphoma...

Enrolling
Relapsed/Refractory Primary Central Nervous System Lymphoma
Drug: Temozolomide
Drug: Tirabrutinib

Phase 3

Ono Pharmaceutical Co., Ltd.

Durham, North Carolina, United States and 28 other locations

2 cohorts to assess safety and efficacy of emavusertib in combination with ibrutinib in participants with R/R primary central nervous system lymphoma...

Enrolling
Refractory Primary Central Nervous System Lymphoma
Relapsed Primary Central Nervous System Lymphoma
Drug: Emavusertib
Drug: Ibrutinib

Phase 1, Phase 2

Curis

Durham, North Carolina, United States and 44 other locations

in treating adults with relapsed/refractory (R/R) mantle cell lymphoma (MCL). This study will also look at the safety of sonrotoclax plus za...

Enrolling
B Cell Lymphoma
Mantle Cell Lymphoma
Drug: Sonrotoclax
Drug: Placebo

Phase 3

BeOne Medicines

Durham, North Carolina, United States and 156 other locations

This is an open-label, multi-center Phase 1b clinical study of oral AS-1763 (docirbrutinib) in patients with CLL/SLL or B-cell NHL who have failed or...

Enrolling
Marginal Zone Lymphoma
Follicular Lymphoma
Drug: Docirbrutinib

Phase 1

Carna Biosciences

Durham, North Carolina, United States and 13 other locations

treating patients with previously untreated stage II-IV follicular lymphoma. Lenalidomide may stimulate the immune system in different ways ...

Active, not recruiting
Ann Arbor Stage III Grade 3 Follicular Lymphoma
Ann Arbor Stage III Grade 2 Follicular Lymphoma
Drug: Ibrutinib
Drug: Lenalidomide

Phase 1

National Cancer Institute (NCI)
National Cancer Institute (NCI)

Chapel Hill, North Carolina, United States and 6 other locations

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