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Find clinical trials for Melanoma in Boston, MA

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Melanoma trials near Boston, MA, USA:

A Phase I/II Study of DYP688 in Patients With Metastatic Uveal Melanoma and Other GNAQ/11 Mutant Melanomas

of DYP688 as a single agent in patients with metastatic uveal melanoma (MUM) and other melanomas harboring GNAQ/11 mutations....

Enrolling
Metastatic Uveal Melanoma
Drug: DYP688

Phase 1, Phase 2

Novartis
Novartis

Boston, Massachusetts, United States and 10 other locations

CDX-301 and Nivolumab or Pembrolizumab as a possible treatment for melanoma.The names of the study drugs involved in this study are:* Person...

Enrolling
Melanoma
Metastatic Melanoma
Drug: Nivolumab
Drug: CDX-301

Phase 1

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Boston, Massachusetts, United States

This research study is studying a targeted therapy called BVD-523 as a possible treatment for advanced uveal melanoma....

Active, not recruiting
Uveal Melanoma
Drug: BVD-523

Phase 2

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Boston, Massachusetts, United States and 1 other location

This research study is studying a combination of drugs as a possible treatment for unresectable or metastatic melanoma.The drugs involved in...

Active, not recruiting
Metastatic Melanoma
Drug: Dabrafenib
Drug: Pembrolizumab

Phase 2

Mass General Brigham
Mass General Brigham

Boston, Massachusetts, United States and 1 other location

This research study is studying a combination of targeted therapies as a possible treatment for advanced melanoma that was found to have a B...

Active, not recruiting
Melanoma
Drug: Cobimetinib
Drug: LY3022855

Phase 1, Phase 2

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Boston, Massachusetts, United States

This research study is studying a combination of targeted therapies as a possible treatment for advanced melanoma that was found to have a B...

Active, not recruiting
Melanoma
Drug: Dabrafenib
Drug: Trametinib

Phase 1, Phase 2

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Boston, Massachusetts, United States

This study observes the antitumor activity, safety, tolerability, PK, and pharmacodynamics in patients with inoperable and/or metastatic melanoma...

Enrolling
Mucosal Melanoma
Cutaneous Melanoma
Drug: Nemvaleukin Alfa Intravenous Less Frequent Dosing
Drug: Nemvaleukin Alfa Intravenous

Phase 2

Mural Oncology

Boston, Massachusetts, United States and 40 other locations

therapy per local standard of care (SoC), best supportive care (BSC)) on protocol survivor follow up) in patients with advanced non-ocular melanoma...

Enrolling
Advanced Melanoma
Drug: Tebentafusp with Pembrolizumab
Drug: Tebentafusp

Phase 2, Phase 3

Immunocore
Immunocore

Boston, Massachusetts, United States and 70 other locations

safety, tolerability, and preliminary efficacy of belzupacap sarotalocan for the treatment of primary indeterminate lesions and small choroidal melanoma...

Active, not recruiting
Ocular Melanoma
Choroidal Melanoma
Device: Suprachoroidal Microinjector
Device: PDT Laser

Phase 2

Aura Biosciences
Aura Biosciences

Boston, Massachusetts, United States and 21 other locations

binimetinib, and pembrolizumab) given together for the treatment of melanoma that:* is advanced or metastatic (spread to other parts of the ...

Active, not recruiting
Melanoma
Drug: Binimetinib
Drug: Encorafenib

Phase 3

Pfizer
Pfizer

Boston, Massachusetts, United States and 227 other locations

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