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Find clinical trials for Melanoma in Charlotte, NC

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Cancer
Carcinoma
Squamous Cell Carcinoma of Head and Neck
Non-Small-Cell Lung Carcinoma
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Squamous Cell Carcinoma
Lung Cancer

Melanoma trials near Charlotte, NC, USA:

Intratumoral Injection of LTX-315 in Combination With Pembrolizumab in Advanced Melanoma (ATLAS-IT-05)

ATLAS-IT-05 is an open-label, single-arm study in patients with advanced melanoma accessible for injections (cutaneous, subcutaneous, lymph ...

Active, not recruiting
Advanced Melanoma
Combination Product: LTX-315 in combination with pembrolizumab

Phase 2

Lytix Biopharma

Charlotte, North Carolina, United States and 9 other locations

to assess nivolumab plus relatlimab fixed-dose combination (FDC) versus nivolumab alone in participants with completely resected stage III-IV melanoma...

Active, not recruiting
Melanoma
Biological: Nivolumab
Biological: Nivolumab + Relatlimab Fixed Dose Combination

Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Charlotte, North Carolina, United States and 171 other locations

and pediatric participants after complete resection of Stage IIB/C melanoma with no evidence of disease (NED) who are at high risk for recur...

Active, not recruiting
Melanoma
Biological: Nivolumab
Other: Placebo

Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Charlotte, North Carolina, United States and 128 other locations

this study is to determine whether relatlimab in combination with nivolumab is more effective than nivolumab by itself in treating unresectable melanoma...

Active, not recruiting
Melanoma
Biological: Nivolumab
Biological: Relatlimab

Phase 2, Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Charlotte, North Carolina, United States and 126 other locations

combined with nivolumab in patients with unresectable or metastatic melanoma. A separate open-label cohort of adults with new, progressive b...

Active, not recruiting
Unresectable or Metastatic Melanoma
Progressive Brain Metastasis
Drug: Placebo in combination with nivolumab
Drug: HBI-8000 in combination with nivolumab

Phase 3

HUYABIO

Charlotte, North Carolina, United States and 138 other locations

The purpose of this study is to determine whether nivolumab is better than ipilimumab to prevent recurrence of melanoma....

Active, not recruiting
Melanoma
Drug: Nivolumab
Other: Placebo matching Nivolumab

Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Charlotte, North Carolina, United States and 135 other locations

Open-Label study evaluating safety and efficacy of SM-020 Gel 1.0% in subjects with Seborrheic Keratoses and Non-Melanoma Skin Cancers (i.e....

Enrolling
Non-Melanoma Skin Cancers
Drug: SM-020 1% Gel

Phase 2

DermBiont
DermBiont

Charlotte, North Carolina, United States

Locations recently updated

In this Phase I trial for subjects with advanced head \& neck cancer, breast cancer, soft tissue sarcoma or melanoma all subjects will recei...

Enrolling
Advanced Solid Tumor Cancer
Combination Product: X-PACT

Phase 1

Immunolight

Charlotte, North Carolina, United States and 3 other locations

to pembrolizumab with respect to RFS as assessed by the investigator in participants with high-risk resected Stage IIB, IIC, III and IV melanoma...

Active, not recruiting
Melanoma
Biological: Pembrolizumab/Vibostolimab
Biological: Pembrolizumab

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Charlotte, North Carolina, United States and 204 other locations

The study will determine Recommended Phase 2 Dose for all study drugs, based on the safety and tolerability of the following combinations: INCAGN0238...

Active, not recruiting
Melanoma
Drug: INCAGN02385
Drug: INCAGN02390

Phase 1, Phase 2

Incyte
Incyte

Huntersville, North Carolina, United States and 16 other locations

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