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Find clinical trials for Melanoma in Charlotte, NC

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Related conditions:

Cancer
Non-Small-Cell Lung Carcinoma
Squamous Cell Carcinoma of Head and Neck
Carcinoma
Renal Cell Carcinoma
Neoplasm Metastasis
Triple Negative Breast Cancer

Melanoma trials near Charlotte, NC, USA:

Intratumoral Injection of LTX-315 in Combination With Pembrolizumab in Advanced Melanoma (ATLAS-IT-05)

ATLAS-IT-05 is an open-label, single-arm study in patients with advanced melanoma accessible for injections (cutaneous, subcutaneous, lymph ...

Active, not recruiting
Advanced Melanoma
Combination Product: LTX-315 in combination with pembrolizumab

Phase 2

Lytix Biopharma

Charlotte, North Carolina, United States and 9 other locations

The study is focused on patients with a type of skin cancer known as melanoma. The aim of the study is to see how safe and effective the com...

Enrolling
Melanoma
Drug: fianlimab
Drug: cemiplimab

Phase 3

Regeneron Pharmaceuticals
Regeneron Pharmaceuticals

Charlotte, North Carolina, United States and 100 other locations

and pediatric participants after complete resection of Stage IIB/C melanoma with no evidence of disease (NED) who are at high risk for recur...

Active, not recruiting
Melanoma
Other: Placebo
Biological: Nivolumab

Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Charlotte, North Carolina, United States and 130 other locations

study is to determine whether relatlimab in combination with nivolumab is more effective than nivolumab monotherapy in treating unresectable melanoma...

Active, not recruiting
Melanoma
Biological: Nivolumab
Biological: Relatlimab

Phase 2, Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Charlotte, North Carolina, United States and 126 other locations

combined with nivolumab in patients with unresectable or metastatic melanoma. A separate open-label cohort of adults with new, progressive b...

Active, not recruiting
Unresectable or Metastatic Melanoma
Progressive Brain Metastasis
Drug: Placebo in combination with nivolumab
Drug: HBI-8000 in combination with nivolumab

Phase 3

HUYABIO

Charlotte, North Carolina, United States and 138 other locations

Open-Label study evaluating safety and efficacy of SM-020 Gel 1.0% in subjects with Seborrheic Keratoses and Non-Melanoma Skin Cancers (i.e....

Enrolling
Non-Melanoma Skin Cancers
Drug: SM-020 1% Gel

Phase 2

DermBiont
DermBiont

Charlotte, North Carolina, United States

In this Phase I trial for subjects with advanced head \& neck cancer, breast cancer, soft tissue sarcoma or melanoma all subjects will recei...

Enrolling
Advanced Solid Tumor Cancer
Combination Product: X-PACT

Phase 1

Immunolight

Charlotte, North Carolina, United States and 3 other locations

This is a first in human, open-label, multi-center Phase 1 / 2 study to evaluate the safety, tolerability, and initial efficacy of AU-007 in patients...

Enrolling
Cutaneous Melanoma
Metastatic Cancer
Drug: Avelumab
Drug: Nivolumab

Phase 1, Phase 2

Aulos Bioscience

Huntersville, North Carolina, United States of America and 15 other locations

The primary objective is to assess the safety and tolerability of TAB004 as monotherapy and in combination with toripalimab in subjects with selected...

Enrolling
Advanced Unresectable Solid Tumor
Metastatic Solid Tumor
Drug: Toripalimab
Drug: TAB004

Phase 1

TopAlliance Biosciences

Huntersville, North Carolina, United States of America and 23 other locations

This is an open-label, dose-exploration and expansion study to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminar...

Active, not recruiting
Malignant Melanoma (Cutaneous)
Non-small Cell Lung Cancer (NSCLC)
Drug: IMM-1-104 + pembrolizumab (Treatment Group E)
Drug: IMM-1-104 + modified Gemcitabine/nab-Paclitaxel (Treatment Group B)

Phase 1, Phase 2

Immuneering Corporation

Charlotte, North Carolina, United States and 19 other locations

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