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Find clinical trials for Melanoma in Dallas, TX

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Squamous Cell Carcinoma

Melanoma trials near Dallas, TX, USA:

(Neo)Adjuvant IDE196 (Darovasertib) in Patients With Localized Ocular Melanoma

Neoadjuvant/adjuvant IDE196 (darovasertib) in patients with primary uveal melanoma...

Enrolling
Uveal Melanoma
Drug: Darovasertib

Phase 2

Ideaya Biosciences

Dallas, Texas, United States and 22 other locations

This study observes the antitumor activity, safety, tolerability, PK, and pharmacodynamics in patients with inoperable and/or metastatic melanoma...

Enrolling
Mucosal Melanoma
Cutaneous Melanoma
Drug: Nemvaleukin Alfa Intravenous Less Frequent Dosing
Drug: Nemvaleukin Alfa Intravenous

Phase 2

Mural Oncology, Inc

Dallas, Texas, United States and 40 other locations

safety, tolerability, and preliminary efficacy of belzupacap sarotalocan for the treatment of primary indeterminate lesions and small choroidal melanoma...

Active, not recruiting
Ocular Melanoma
Choroidal Melanoma
Device: Suprachoroidal Microinjector
Device: PDT Laser

Phase 2

Aura Biosciences
Aura Biosciences

Dallas, Texas, United States and 21 other locations

binimetinib, and pembrolizumab) given together for the treatment of melanoma that:is advanced or metastatic (spread to other parts of the bo...

Active, not recruiting
Melanoma
Drug: Binimetinib
Drug: Encorafenib

Phase 3

Pfizer
Pfizer

Carrollton, Texas, United States and 227 other locations

efficacy of belzupacap sarotalocan (bel-sar) compared to sham control in patients with primary indeterminate lesions (IL) or small choroidal melanoma...

Enrolling
Ocular Melanoma
Choroidal Melanoma
Device: Suprachoroidal Microinjector
Drug: Sham Treatment

Phase 3

Aura Biosciences
Aura Biosciences

Dallas, Texas, United States and 37 other locations

Approximately 40 participants with locally advanced or metastatic melanoma will be enrolled in 20 sites in the United States into 1 of the f...

Active, not recruiting
Locally Advanced Unresectable or Metastatic Melanoma
Drug: Selinexor
Drug: Pembrolizumab

Phase 2

Karyopharm Therapeutics
Karyopharm Therapeutics

Dallas, Texas, United States and 12 other locations

antigen (HLA)-A*02:01 negative participants with metastatic uveal melanoma (MUM) who will be randomized to receive either IDE196 + crizotini...

Enrolling
Metastatic Uveal Melanoma
Drug: IDE196
Drug: Nivolumab

Phase 2, Phase 3

Ideaya Biosciences

Dallas, Texas, United States and 62 other locations

A Phase 2 study to investigate the efficacy and safety of lerapolturev alone or in combination with a programmed death receptor-1 (anti-PD-1) inhibit...

Active, not recruiting
Melanoma
Biological: Lerapolturev
Biological: Anti-PD-1 Checkpoint Inhibitor

Phase 2

Istari Oncology

Dallas, Texas, United States and 11 other locations

to assess nivolumab plus relatlimab fixed-dose combination (FDC) versus nivolumab alone in participants with completely resected stage III-IV melanoma...

Active, not recruiting
Melanoma
Biological: Nivolumab
Biological: Nivolumab + Relatlimab Fixed Dose Combination

Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Dallas, Texas, United States and 171 other locations

This is an open-label, 3-arm, fixed-sequence study to evaluate the effect of single and multiple oral doses of encorafenib in combination with binime...

Active, not recruiting
Metastatic Melanoma
Advanced Solid Tumors
Drug: rosuvastatin
Drug: dextromethorphan

Phase 1

Pfizer
Pfizer

Dallas, Texas, United States and 27 other locations

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