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Find clinical trials for Melanoma in Indianapolis, IN

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Related conditions:

Cancer
Carcinoma
Squamous Cell Carcinoma of Head and Neck
Renal Cell Carcinoma
Non-Small-Cell Lung Carcinoma
Lung Cancer
Squamous Cell Carcinoma

Melanoma trials near Indianapolis, IN, USA:

A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors

with Opdualag to subjects with unresectable or metastatic melanoma.Subjects in dose escalation (Cohorts 1 through 3) and dose expansion (Coh...

Enrolling
Melanoma Stage IV
Melanoma Stage III
Drug: Opdualag
Biological: KB707

Phase 1, Phase 2

Krystal Biotech

Indianapolis, Indiana, United States and 13 other locations

This is a Phase 1b/2, multi-center, open label umbrella study of patients ≥12 years of age with recurrent, progressive, or refractory melanoma...

Active, not recruiting
Melanoma
Spitzoid Melanoma
Drug: Tovorafenib
Drug: Pimasertib

Phase 1, Phase 2

Day One Biopharmaceuticals

Indianapolis, Indiana, United States and 19 other locations

drug.There are 2 parts in this trial. In one part, participants have melanoma that has come back after treatment or can't be removed by surg...

Active, not recruiting
Melanoma
Carcinoma, Non-Small- Cell Lung
Drug: SEA-CD40
Drug: carboplatin

Phase 2

Seagen
Seagen

Indianapolis, Indiana, United States and 28 other locations

A first-in-human, Phase I, open-label, multicenter study of WTX-124 administered as monotherapy and in combination with pembrolizumab to patients wit...

Enrolling
Advanced Solid Tumor
Metastatic Solid Tumor
Drug: pembrolizumab
Drug: WTX-124

Phase 1

Werewolf Therapeutics

Indianapolis, Indiana, United States and 7 other locations

TTX-080-001 is a Phase 1, open label, dose escalation and dose expansion clinical study to determine the safety, tolerability, and recommended Phase...

Enrolling
Cancer
Drug: cetuximab
Drug: FOLFIRI

Phase 1

Tizona Therapeutics

Indianapolis, Indiana, United States and 38 other locations

This is an open-label, multi-center, single arm, Phase II study to evaluate the efficacy and safety of T-DXd for the treatment of unresectable and/or...

Active, not recruiting
Advanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,Breast
Drug: Trastuzumab deruxtecan

Phase 2

AstraZeneca
AstraZeneca

Muncie, Indiana, United States and 29 other locations

VET3-TGI is an oncolytic immunotherapy designed to treat advanced cancers. VET3-TGI has not been given to human patients yet, and the current study i...

Enrolling
Melanoma Stage IV
Merkel Cell Carcinoma of Skin
Drug: VET3-TGI
Drug: Pembrolizumab

Phase 1

KaliVir Immunotherapeutics

Indianapolis, Indiana, United States and 3 other locations

This is a Phase 1/2A study of GV20-0251 being developed for the treatment of participants with advanced solid tumors, who are refractory to approved...

Enrolling
Cutaneous Melanoma
Squamous Head and Neck Carcinoma
Biological: GV20-0251 and Pembrolizumab [KEYTRUDA®]
Biological: GV20-0251

Phase 1, Phase 2

GV20 Therapeutics

Indianapolis, Indiana, United States and 12 other locations

or fluocinolone acetonide (FAc) intravitreal implant compared with observation on long-term visual acuity following treatment of choroidal melanoma...

Enrolling
Radiation Retinopathy
Visual Impairment
Drug: Faricimab
Drug: fluocinolone acetonide

Phase 3

Jaeb Center for Health Research
Jaeb Center for Health Research

Indianapolis, Indiana, United States and 15 other locations

Locations recently updated

This trial will be a randomized controlled study comparing the efficacy and safety of intraoperative radiation therapy using GammaTilesTM (GT) versus...

Enrolling
Brain Metastases
Radiation: Stereotactic Radiation Therapy
Device: Gamma Tile-Surgically Targeted Radiation Therapy (STaRT)

Phase 3

GT Medical Technologies

Indianapolis, Indiana, United States and 33 other locations

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