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Prospective, interventional multicenter study evaluating adoptive cell therapy (ACT) via infusion of LN-144 (autologous TIL) followed by interleukin...
Phase 2
Indianapolis, Indiana, United States and 56 other locations
with Opdualag to subjects with unresectable or metastatic melanoma.Subjects in dose escalation (Cohorts 1 through 3) and dose expansion (Coh...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 13 other locations
This is a Phase 1b/2, multi-center, open label umbrella study of patients ≥12 years of age with recurrent, progressive, or refractory melanoma...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 19 other locations
drug.There are 2 parts in this trial. In one part, participants have melanoma that has come back after treatment or can't be removed by surg...
Phase 2
Indianapolis, Indiana, United States and 28 other locations
A first-in-human, Phase I, open-label, multicenter study of WTX-124 administered as monotherapy and in combination with pembrolizumab to patients wit...
Phase 1
Indianapolis, Indiana, United States and 7 other locations
TTX-080-001 is a Phase 1, open label, dose escalation and dose expansion clinical study to determine the safety, tolerability, and recommended Phase...
Phase 1
Indianapolis, Indiana, United States and 38 other locations
This is a Phase 1, First-in-Human (FIH), open-label, multicenter, dose escalation and dose expansion study to evaluate the safety, tolerability, phar...
Phase 1
Indianapolis, Indiana, United States and 5 other locations
This is an open-label, multi-center, single arm, Phase II study to evaluate the efficacy and safety of T-DXd for the treatment of unresectable and/or...
Phase 2
Muncie, Indiana, United States and 29 other locations
VET3-TGI is an oncolytic immunotherapy designed to treat advanced cancers. VET3-TGI has not been given to human patients yet, and the current study i...
Phase 1
Indianapolis, Indiana, United States and 3 other locations
This is a Phase 1/2A study of GV20-0251 being developed for the treatment of participants with advanced solid tumors, who are refractory to approved...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 12 other locations
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