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Find clinical trials for Melanoma in Indianapolis, IN

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Related conditions:

Cancer
Carcinoma
Squamous Cell Carcinoma of Head and Neck
Non-Small-Cell Lung Carcinoma
Renal Cell Carcinoma
Lung Cancer
Triple Negative Breast Cancer

Melanoma trials near Indianapolis, IN, USA:

A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors

with Opdualag to subjects with unresectable or metastatic melanoma.Subjects in dose escalation (Cohorts 1 through 3) and dose expansion (Coh...

Enrolling
Melanoma Stage IV
Melanoma Stage III
Drug: Opdualag
Drug: KEYTRUDA ®( Pembrolizumab)

Phase 1, Phase 2

Krystal Biotech

Indianapolis, Indiana, United States and 13 other locations

This is a Phase 1b/2, multi-center, open label umbrella study of patients ≥12 years of age with recurrent, progressive, or refractory melanoma...

Active, not recruiting
Melanoma
Spitzoid Melanoma
Drug: Tovorafenib
Drug: Pimasertib

Phase 1, Phase 2

Day One Biopharmaceuticals

Indianapolis, Indiana, United States and 19 other locations

The purpose of this study is to evaluate the safety and tolerability of CFT1946 as well as to determine the maximum tolerated dose (MTD) and/or the r...

Enrolling
Melanoma
ATC
Drug: Trametinib
Drug: Cetuximab

Phase 1, Phase 2

C4 Therapeutics

Indianapolis, Indiana, United States and 25 other locations

A first-in-human, Phase I, open-label, multicenter study of WTX-124 administered as monotherapy and in combination with pembrolizumab to patients wit...

Enrolling
Advanced Solid Tumor
Metastatic Solid Tumor
Drug: WTX-124
Drug: pembrolizumab

Phase 1

Werewolf Therapeutics

Indianapolis, Indiana, United States and 7 other locations

TTX-080-001 is a Phase 1, open label, dose escalation and dose expansion clinical study to determine the safety, tolerability, and recommended Phase...

Enrolling
Cancer
Drug: cetuximab
Drug: FOLFIRI

Phase 1

Tizona Therapeutics

Indianapolis, Indiana, United States and 38 other locations

This is an open-label, multi-center, single arm, Phase II study to evaluate the efficacy and safety of T-DXd for the treatment of unresectable and/or...

Active, not recruiting
Advanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,Breast
Drug: Trastuzumab deruxtecan

Phase 2

AstraZeneca
AstraZeneca

Muncie, Indiana, United States and 29 other locations

VET3-TGI is an oncolytic immunotherapy designed to treat advanced cancers. VET3-TGI has not been given to human patients yet, and the current study i...

Enrolling
Melanoma Stage IV
Merkel Cell Carcinoma of Skin
Drug: VET3-TGI
Drug: Pembrolizumab

Phase 1

KaliVir Immunotherapeutics

Indianapolis, Indiana, United States and 5 other locations

This is a Phase 1/2A study of GV20-0251 being developed for the treatment of participants with advanced solid tumors, who are refractory to approved...

Enrolling
Cutaneous Melanoma
Squamous Head and Neck Carcinoma
Biological: GV20-0251 and Pembrolizumab [KEYTRUDA®]
Biological: GV20-0251

Phase 1, Phase 2

GV20 Therapeutics

Indianapolis, Indiana, United States and 12 other locations

or fluocinolone acetonide (FAc) intravitreal implant compared with observation on long-term visual acuity following treatment of choroidal melanoma...

Enrolling
Radiation Retinopathy
Visual Impairment
Drug: Faricimab
Drug: fluocinolone acetonide

Phase 3

Jaeb Center for Health Research
Jaeb Center for Health Research

Indianapolis, Indiana, United States and 17 other locations

This trial will be a randomized controlled study comparing the efficacy and safety of intraoperative radiation therapy using GammaTilesTM (GT) versus...

Enrolling
Brain Metastases
Radiation: Stereotactic Radiation Therapy
Device: Gamma Tile-Surgically Targeted Radiation Therapy (STaRT)

Phase 3

GT Medical Technologies

Indianapolis, Indiana, United States and 37 other locations

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