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Find clinical trials for Melanoma in Indianapolis, IN

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Related conditions:

Cancer
Carcinoma
Squamous Cell Carcinoma of Head and Neck
Non-Small-Cell Lung Carcinoma
Renal Cell Carcinoma
Lung Cancer
Squamous Cell Carcinoma

Melanoma trials near Indianapolis, IN, USA:

Study of Lifileucel (LN-144), Autologous Tumor Infiltrating Lymphocytes, in the Treatment of Patients With Metastatic Melanoma

Prospective, interventional multicenter study evaluating adoptive cell therapy (ACT) via infusion of LN-144 (autologous TIL) followed by interleukin...

Active, not recruiting
Metastatic Melanoma
Biological: Lifileucel

Phase 2

Iovance Biotherapeutics

Indianapolis, Indiana, United States and 56 other locations

This is a Phase 1b/2, multi-center, open label umbrella study of patients ≥12 years of age with recurrent, progressive, or refractory melanoma...

Active, not recruiting
Melanoma
Spitzoid Melanoma
Drug: Tovorafenib
Drug: Pimasertib

Phase 1, Phase 2

Day One Biopharmaceuticals

Indianapolis, Indiana, United States and 19 other locations

drug.There are 2 parts in this trial. In one part, participants have melanoma that has come back after treatment or can't be removed by surg...

Active, not recruiting
Melanoma
Carcinoma, Non-Small- Cell Lung
Drug: SEA-CD40
Drug: carboplatin

Phase 2

Seagen
Seagen

Indianapolis, Indiana, United States and 28 other locations

Researchers are looking for new ways to treat children with different types of melanoma (skin cancer), solid tumors, and lymphomas (blood ca...

Enrolling
Melanoma
Solid Tumor
Biological: Pembrolizumab

Phase 1, Phase 2

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Indianapolis, Indiana, United States and 13 other locations

KB707-01 is a Phase 1, open-label, multicenter, dose escalation and expansion study to evaluate the safety and tolerability of KB707 in adults with l...

Enrolling
Melanoma Stage IV
Melanoma Stage III
Biological: KB707

Phase 1

Krystal Biotech

Indianapolis, Indiana, United States and 13 other locations

A first-in-human, Phase I, open-label, multicenter study of WTX-124 administered as monotherapy and in combination with pembrolizumab to patients wit...

Enrolling
Advanced Solid Tumor
Metastatic Solid Tumor
Drug: pembrolizumab
Drug: WTX-124

Phase 1

Werewolf Therapeutics

Indianapolis, Indiana, United States and 7 other locations

TTX-080-001 is a Phase 1, open label, dose escalation and dose expansion clinical study to determine the safety, tolerability, and recommended Phase...

Active, not recruiting
Cancer
Drug: cetuximab
Drug: TTX-080

Phase 1

Tizona Therapeutics

Indianapolis, Indiana, United States and 39 other locations

This is a Phase 1, First-in-Human (FIH), open-label, multicenter, dose escalation and dose expansion study to evaluate the safety, tolerability, phar...

Enrolling
NF1 Mutation
Advanced Solid Tumor
Drug: ABM-168

Phase 1

ABM Therapeutics

Indianapolis, Indiana, United States and 5 other locations

This is an open-label, multi-center, single arm, Phase II study to evaluate the efficacy and safety of T-DXd for the treatment of unresectable and/or...

Active, not recruiting
Advanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,Breast
Drug: Trastuzumab deruxtecan

Phase 2

AstraZeneca
AstraZeneca

Muncie, Indiana, United States and 29 other locations

This is a Phase 1/2A study of GV20-0251 being developed for the treatment of participants with advanced solid tumors, who are refractory to approved...

Enrolling
Cutaneous Melanoma
Squamous Head and Neck Carcinoma
Biological: GV20-0251 and Pembrolizumab [KEYTRUDA®]
Biological: GV20-0251

Phase 1, Phase 2

GV20 Therapeutics

Indianapolis, Indiana, United States and 12 other locations

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