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This study observes the antitumor activity, safety, tolerability, PK, and pharmacodynamics in patients with inoperable and/or metastatic melanoma...
Phase 2
Jacksonville, Florida, United States and 40 other locations
therapy per local standard of care (SoC), best supportive care (BSC)) on protocol survivor follow up) in patients with advanced non-ocular melanoma...
Phase 2, Phase 3
Jacksonville, Florida, United States and 70 other locations
not worse than nivolumab + relatlimab FDC intravenous (IV) administration in participants with previously untreated metastatic or unresectable melanoma...
Phase 3
Jacksonville, Florida, United States and 189 other locations
This is a single arm phase II clinical trial of Ipilimumab and Nivolumab in patients with resected mucosal melanoma. Ipilimumab (1 mg/kg) an...
Phase 2
Jacksonville, Florida, United States and 6 other locations
this study is to determine whether relatlimab in combination with nivolumab is more effective than nivolumab by itself in treating unresectable melanoma...
Phase 2, Phase 3
Jacksonville, Florida, United States and 126 other locations
combined with nivolumab on patients with unresectable or metastatic melanoma and eligible patients who are not adolescents or patients with ...
Phase 3
Jacksonville, Florida, United States and 141 other locations
The purpose of this study is to determine whether nivolumab is better than ipilimumab to prevent recurrence of melanoma....
Phase 3
Jacksonville, Florida, United States and 135 other locations
(PROs) of autogene cevumeran (RO7198457) plus pembrolizumab compared with pembrolizumab alone in patients with previously untreated advanced melanoma...
Phase 2
Jacksonville, Florida, United States and 56 other locations
placebo in participants with surgically resected high-risk Stage II melanoma. Participants in Part 1 will receive either pembrolizumab or pl...
Phase 3
Jacksonville, Florida, United States and 158 other locations
The purpose of this study is to show that Nivolumab and/or Nivolumab in combination with Ipilimumab will extend progression free survival and overall...
Phase 3
Jacksonville, Florida, United States and 149 other locations
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