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Find clinical trials for Melanoma in Jacksonville, FL

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Squamous Cell Carcinoma

Melanoma trials near Jacksonville, FL, USA:

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

therapy per local standard of care \[SoC\], best supportive care \[BSC\] on protocol survivor follow up) in patients with advanced non-ocular melanoma...

Enrolling
Advanced Melanoma
Drug: Tebentafusp with Pembrolizumab
Drug: Tebentafusp

Phase 3

Immunocore
Immunocore

Jacksonville, Florida, United States and 65 other locations

This study observes the antitumor activity, safety, tolerability, PK, and pharmacodynamics in patients with inoperable and/or metastatic melanoma...

Enrolling
Mucosal Melanoma
Cutaneous Melanoma
Drug: Nemvaleukin Alfa Intravenous Less Frequent Dosing
Drug: Pembrolizumab

Phase 2

Mural Oncology

Jacksonville, Florida, United States and 43 other locations

not worse than nivolumab + relatlimab FDC intravenous (IV) administration in participants with previously untreated metastatic or unresectable melanoma...

Enrolling
Melanoma
Drug: Nivolumab + Relatlimab
Drug: rHuPH20

Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Jacksonville, Florida, United States and 189 other locations

This is a single arm phase II clinical trial of Ipilimumab and Nivolumab in patients with resected mucosal melanoma. Ipilimumab (1 mg/kg) an...

Active, not recruiting
Mucosal Melanoma
Drug: Nivolumab
Drug: Ipilimumab

Phase 2

Robert R. McWilliams, MD

Jacksonville, Florida, United States and 6 other locations

combined with nivolumab in patients with unresectable or metastatic melanoma. A separate open-label cohort of adults with new, progressive b...

Active, not recruiting
Unresectable or Metastatic Melanoma
Progressive Brain Metastasis
Drug: Placebo in combination with nivolumab
Drug: HBI-8000 in combination with nivolumab

Phase 3

HUYABIO

Jacksonville, Florida, United States and 138 other locations

this study is to determine whether relatlimab in combination with nivolumab is more effective than nivolumab by itself in treating unresectable melanoma...

Active, not recruiting
Melanoma
Biological: Nivolumab
Biological: Relatlimab

Phase 2, Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Jacksonville, Florida, United States and 126 other locations

This study will test the safety of a drug called PF-08046049/SGN-BB228 in participants with melanoma and other solid tumors that are hard to...

Enrolling
Cutaneous Melanoma
Non-small Cell Lung Cancer
Drug: PF-08046049

Phase 1

Seagen
Seagen

Jacksonville, Florida, United States and 21 other locations

(IMC-F106C) plus nivolumab compared to standard nivolumab regimens in HLA-A\*02:01-positive participants with previously untreated advanced melanoma...

Enrolling
Advanced Melanoma
Biological: Brenetafusp
Biological: Nivolumab + Relatlimab

Phase 3

Immunocore
Immunocore

Jacksonville, Florida, United States and 97 other locations

(PROs) of autogene cevumeran (RO7198457) plus pembrolizumab compared with pembrolizumab alone in patients with previously untreated advanced melanoma...

Active, not recruiting
Advanced Melanoma
Drug: Pembrolizumab
Biological: Autogene cevumeran

Phase 2

Genentech
Genentech

Jacksonville, Florida, United States and 56 other locations

placebo in participants with surgically resected high-risk Stage II melanoma. Participants in Part 1 will receive either pembrolizumab or pl...

Active, not recruiting
Melanoma
Other: Placebo
Biological: Pembrolizumab

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Jacksonville, Florida, United States and 158 other locations

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