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Find clinical trials for Melanoma in Miami, FL

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Squamous Cell Carcinoma

Melanoma trials near Miami, FL, USA:

(Neo)Adjuvant IDE196 (Darovasertib) in Patients With Localized Ocular Melanoma

Neoadjuvant/adjuvant IDE196 (darovasertib) in patients with primary uveal melanoma...

Enrolling
Uveal Melanoma
Drug: Darovasertib

Phase 2

Ideaya Biosciences

Miami, Florida, United States and 22 other locations

research is to test if a combination treatment of nivolumab and relatlimab will result in tumor reduction in patients with metastatic uveal melanoma...

Active, not recruiting
Metastatic Uveal Melanoma
Drug: Relatlimab
Drug: Nivolumab

Phase 2

Jose Lutzky, MD

Miami, Florida, United States

Approximately 40 participants with locally advanced or metastatic melanoma will be enrolled in 20 sites in the United States into 1 of the f...

Active, not recruiting
Locally Advanced Unresectable or Metastatic Melanoma
Drug: Selinexor
Drug: Pembrolizumab

Phase 2

Karyopharm Therapeutics
Karyopharm Therapeutics

Plantation, Florida, United States and 12 other locations

Prospective, interventional multicenter study evaluating adoptive cell therapy (ACT) via infusion of LN-144 (autologous TIL) followed by interleukin...

Active, not recruiting
Metastatic Melanoma
Biological: Lifileucel

Phase 2

Iovance Biotherapeutics

Miami, Florida, United States and 56 other locations

To evaluate the overall survival of HLA-A\*0201 positive adult patients with previously untreated advanced UM receiving IMCgp100 compared to Investig...

Active, not recruiting
Uveal Melanoma
Biological: IMCgp100
Biological: Pembrolizumab

Phase 2

Immunocore
Immunocore

Miami, Florida, United States and 55 other locations

tolerability, PK and antitumor activities of IN10018 as monotherapy and in combination with cobimetinib in subjects with metastatic uveal melanoma...

Enrolling
Metastatic Melanoma
Drug: Cobimetinib
Biological: Atezolizumab

Phase 1

InxMed

Miami, Florida, United States and 7 other locations

antigen (HLA)-A\*02:01 negative participants with metastatic uveal melanoma (MUM) who will be randomized to receive either IDE196 + crizotin...

Enrolling
Metastatic Uveal Melanoma
Drug: IDE196
Drug: Nivolumab

Phase 2, Phase 3

Ideaya Biosciences

Miami, Florida, United States and 64 other locations

attracting MDSCs. This first study will enroll participants with melanoma, as melanoma cancer has been shown to be able to attract ...

Enrolling
Melanoma Stage IV
Melanoma Stage III
Drug: SX-682
Biological: Pembrolizumab

Phase 1

Syntrix Biosystems

Miami, Florida, United States and 5 other locations

patients with unresectable Stage III or IV melanoma. The contributions of BNT111 and cemiplimab will be delineated in single agent...

Active, not recruiting
Melanoma Stage IV
Melanoma Stage III
Biological: BNT111
Biological: Cemiplimab

Phase 2

BioNTech
BioNTech

Miami, Florida, United States and 52 other locations

to assess nivolumab plus relatlimab fixed-dose combination (FDC) versus nivolumab alone in participants with completely resected stage III-IV melanoma...

Active, not recruiting
Melanoma
Biological: Nivolumab
Biological: Nivolumab + Relatlimab Fixed Dose Combination

Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Miami, Florida, United States and 171 other locations

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