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Find clinical trials for Melanoma in Phoenix, AZ

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Uveal Melanoma

Melanoma trials near Phoenix, AZ, USA:

(Neo)Adjuvant IDE196 (Darovasertib) in Patients With Localized Ocular Melanoma

Neoadjuvant/adjuvant IDE196 (darovasertib) in patients with primary uveal melanoma...

Active, not recruiting
Uveal Melanoma
Drug: Darovasertib

Phase 2

Ideaya Biosciences

Scottsdale, Arizona, United States and 17 other locations

This is a Phase 3, randomized, multi-center, open-label study of neoadjuvant darovasertib in subjects with primary non-metastatic uveal melanoma...

Enrolling
Uveal Melanoma
Procedure: Primary Local Therapy
Drug: Darovasertib

Phase 3

Ideaya Biosciences

Scottsdale, Arizona, United States and 93 other locations

manner the recurrence-free survival (RFS) of Stage IIIB/C/D melanoma patients with respect to the standard of care (surgery and adjuvant the...

Enrolling
Melanoma Stage IIID
Melanoma Stage IIIC
Drug: Adjuvant therapy
Procedure: Surgery

Phase 3

Philogen
Philogen

Phoenix, Arizona, United States and 36 other locations

therapy per local standard of care \[SoC\], best supportive care \[BSC\] on protocol survivor follow up) in patients with advanced non-ocular melanoma...

Enrolling
Advanced Melanoma
Drug: Tebentafusp with Pembrolizumab
Drug: Tebentafusp

Phase 3

Immunocore
Immunocore

Phoenix, Arizona, United States and 81 other locations

This study is being done to find the best dose of an investigational drug called NBM-BMX for people with metastatic uveal melanoma, a type o...

Enrolling
Uveal Melanoma, Metastatic
Metastatic Uveal Melanoma
Drug: NBM-BMX Capsule are proprietary products developed by Novelwise Pharmaceutical Corporation (Novelwise) for treatment of patients suffering from cancers.

Phase 1, Phase 2

Novelwise Pharmaceutical

Scottsdale, Arizona, United States and 2 other locations

and overall survival (OS) for patients with NRAS-mutant (NRASm) melanoma who are randomized to receive the combination of naporafenib + tram...

Active, not recruiting
Advanced or Metastatic NRAS-mutant Melanoma
Drug: Trametinib
Drug: Naporafenib

Phase 3

Erasca

Phoenix, Arizona, United States and 58 other locations

The study is focused on patients with a type of skin cancer known as melanoma. The aim of the study is to see how safe and effective the com...

Enrolling
Melanoma
Drug: fianlimab
Drug: cemiplimab

Phase 3

Regeneron Pharmaceuticals
Regeneron Pharmaceuticals

Chandler, Arizona, United States and 109 other locations

antigen (HLA)-A\*02:01 negative participants with metastatic uveal melanoma (MUM) who will be randomized to receive either IDE196 + crizotin...

Active, not recruiting
Metastatic Uveal Melanoma
Drug: IDE196
Drug: Nivolumab

Phase 2, Phase 3

Ideaya Biosciences

Scottsdale, Arizona, United States and 67 other locations

Locations recently updated

The goal of this clinical trial is to learn if DOC1021 + pIFN will be safe and will lead to tumor responses in patients with refractory melanoma...

Enrolling
Refractory Melanoma
Drug: pIFN (peginterferon alfa-2a)
Biological: DOC1021

Phase 1, Phase 2

Diakonos Oncology Corporation

Scottsdale, Arizona, United States and 5 other locations

and pharmacokinetic profiles of botensilimab as monotherapy and in combination with balstilimab in participants with advanced cutaneous melanoma...

Active, not recruiting
Advanced Melanoma
Drug: Botensilimab
Drug: Balstilimab

Phase 2

Agenus
Agenus

Scottsdale, Arizona, United States and 50 other locations

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