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Find clinical trials for Melanoma in San Antonio, TX

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Melanoma trials near San Antonio, TX, USA:

A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors

cell death protein-1 (PD-1) inhibitor, in patients with metastatic melanomas or advanced solid tumors. Our hypothesis is that restoration of...

Enrolling
Mucosal Melanoma
Melanoma
Drug: Phase 1b: APG-115+pembrolizumab

Phase 1, Phase 2

Ascentage Pharma Group
Ascentage Pharma Group

San Antonio, Texas, United States and 20 other locations

efficacy of belzupacap sarotalocan (bel-sar) compared to sham control in patients with primary indeterminate lesions (IL) or small choroidal melanoma...

Enrolling
Ocular Melanoma
Choroidal Melanoma
Device: Suprachoroidal Microinjector
Drug: Sham Treatment

Phase 3

Aura Biosciences
Aura Biosciences

San Antonio, Texas, United States and 37 other locations

Substudy 02B is part of a larger research study where researchers are looking for new ways to treat advanced melanoma that has not been trea...

Enrolling
Melanoma
Drug: Lenvatinib
Biological: Vibostolimab

Phase 1, Phase 2

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

San Antonio, Texas, United States and 58 other locations

the recommended Phase 2 dose (RP2D). The study comprises a Part 1 (Dose Escalation) and a Part 2 (Dose Expansion) in solid organ tumors (melanoma...

Enrolling
Advanced/Metastatic Solid Tumor
Drug: KZR-261

Phase 1

Kezar Life Sciences

San Antonio, Texas, United States and 8 other locations

This Phase 1/2, first-in-human, open-label, multicenter study follows a 3+3 ascending dose escalation design to determine the MTD/RP2D and to charact...

Enrolling
Solid Tumor, Adult
Biological: Pembrolizumab - anti-PD-1 antibody
Drug: LNS8801 -Small molecule, orally bioavailable, selective agonist of GPER

Phase 1, Phase 2

Linnaeus Therapeutics

San Antonio, Texas, United States and 9 other locations

This study is an open-label, Phase 1, multicenter study to evaluate the safety, tolerability, PK, and PD profiles of AGEN2373 as a monotherapy and in...

Active, not recruiting
Advanced Cancer
Drug: Botensilimab
Drug: AGEN2373

Phase 1

Agenus
Agenus

San Antonio, Texas, United States and 11 other locations

A first-in-human, Phase I, open-label, multicenter study of WTX-124 administered as monotherapy and in combination with pembrolizumab to patients wit...

Enrolling
Advanced Solid Tumor
Metastatic Solid Tumor
Drug: pembrolizumab
Drug: WTX-124

Phase 1

Werewolf Therapeutics

San Antonio, Texas, United States and 7 other locations

Locations recently updated

.* Melanoma: Skin cancer that develops when melanocytes (the cells that give the skin its tan or brown color) start to grow out of control.A...

Enrolling
Melanoma
Urothelial Cancer
Biological: bevacizumab
Biological: sasanlimab

Phase 1

Pfizer
Pfizer

San Antonio, Texas, United States and 6 other locations

This is a Phase 1/2, first-in-human, open-label, dose escalation and dose-expansion study of E-602, administered alone and in combination with cemipl...

Active, not recruiting
Melanoma
Breast Cancer
Biological: E-602
Biological: Cemiplimab

Phase 1, Phase 2

Palleon Pharmaceuticals

San Antonio, Texas, United States and 12 other locations

TTX-080-001 is a Phase 1, open label, dose escalation and dose expansion clinical study to determine the safety, tolerability, and recommended Phase...

Active, not recruiting
Cancer
Drug: pembrolizumab
Drug: TTX-080

Phase 1

Tizona Therapeutics

San Antonio, Texas, United States and 39 other locations

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