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cell death protein-1 (PD-1) inhibitor, in patients with metastatic melanomas or advanced solid tumors. Our hypothesis is that restoration of...
Phase 1, Phase 2
San Antonio, Texas, United States and 20 other locations
efficacy of belzupacap sarotalocan (bel-sar) compared to sham control in patients with primary indeterminate lesions (IL) or small choroidal melanoma...
Phase 3
San Antonio, Texas, United States and 64 other locations
The study is being conducted in patients with advanced skin cancer (melanoma) who had previously been treated with fianlimab and cemiplimab ...
Phase 2
San Antonio, Texas, United States and 5 other locations
Substudy 02B is part of a larger research study where researchers are looking for new ways to treat advanced melanoma that has not been trea...
Phase 1, Phase 2
San Antonio, Texas, United States and 59 other locations
the recommended Phase 2 dose (RP2D). The study comprises a Part 1 (Dose Escalation) and a Part 2 (Dose Expansion) in solid organ tumors (melanoma...
Phase 1
San Antonio, Texas, United States and 11 other locations
This Phase 1/2, first-in-human, open-label, multicenter study follows a 3+3 ascending dose escalation design to determine the MTD/RP2D and to charact...
Phase 1, Phase 2
San Antonio, Texas, United States and 9 other locations
This is a first in human, open-label, multi-center Phase 1 / 2 study to evaluate the safety, tolerability, and initial efficacy of AU-007 in patients...
Phase 1, Phase 2
San Antonio, Texas, United States and 12 other locations
This study will evaluate the safety, efficacy, optimal dose, and pharmacokinetics (PK) of BNT326 as monotherapy (Part 1) and as combination treatment...
Phase 1, Phase 2
San Antonio, Texas, United States and 6 other locations
This is an open-label, multicenter, first-in-human dose-escalation and expansion Phase 1-2 study designed to determine the safety, tolerability, phar...
Phase 1, Phase 2
San Antonio, Texas, United States and 3 other locations
A first-in-human, Phase I, open-label, multicenter study of WTX-124 administered as monotherapy and in combination with pembrolizumab to patients wit...
Phase 1
San Antonio, Texas, United States and 13 other locations
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