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cell death protein-1 (PD-1) inhibitor, in patients with metastatic melanomas or advanced solid tumors. Our hypothesis is that restoration of...
Phase 1, Phase 2
San Antonio, Texas, United States and 20 other locations
efficacy of belzupacap sarotalocan (bel-sar) compared to sham control in patients with primary indeterminate lesions (IL) or small choroidal melanoma...
Phase 3
San Antonio, Texas, United States and 54 other locations
The study is being conducted in patients with advanced skin cancer (melanoma) who had previously been treated with fianlimab and cemiplimab ...
Phase 2
San Antonio, Texas, United States and 1 other location
Substudy 02B is part of a larger research study where researchers are looking for new ways to treat advanced melanoma that has not been trea...
Phase 1, Phase 2
San Antonio, Texas, United States and 61 other locations
the recommended Phase 2 dose (RP2D). The study comprises a Part 1 (Dose Escalation) and a Part 2 (Dose Expansion) in solid organ tumors (melanoma...
Phase 1
San Antonio, Texas, United States and 11 other locations
This Phase 1/2, first-in-human, open-label, multicenter study follows a 3+3 ascending dose escalation design to determine the MTD/RP2D and to charact...
Phase 1, Phase 2
San Antonio, Texas, United States and 9 other locations
This is an open-label, multicenter, first-in-human dose-escalation and expansion Phase 1-2 study designed to determine the safety, tolerability, phar...
Phase 1, Phase 2
San Antonio, Texas, United States and 3 other locations
A first-in-human, Phase I, open-label, multicenter study of WTX-124 administered as monotherapy and in combination with pembrolizumab to patients wit...
Phase 1
San Antonio, Texas, United States and 10 other locations
TTX-080-001 is a Phase 1, open label, dose escalation and dose expansion clinical study to determine the safety, tolerability, and recommended Phase...
Phase 1
San Antonio, Texas, United States and 38 other locations
This is a Phase 1, FIH, Dose Escalation and Dose Expansion study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) e...
Phase 1
San Antonio, Texas, United States and 14 other locations
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