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cell death protein-1 (PD-1) inhibitor, in patients with metastatic melanomas or advanced solid tumors. Our hypothesis is that restoration of...
Phase 1, Phase 2
San Antonio, Texas, United States and 20 other locations
efficacy of belzupacap sarotalocan (bel-sar) compared to sham control in patients with primary indeterminate lesions (IL) or small choroidal melanoma...
Phase 3
San Antonio, Texas, United States and 46 other locations
Substudy 02B is part of a larger research study where researchers are looking for new ways to treat advanced melanoma that has not been trea...
Phase 1, Phase 2
San Antonio, Texas, United States and 60 other locations
the recommended Phase 2 dose (RP2D). The study comprises a Part 1 (Dose Escalation) and a Part 2 (Dose Expansion) in solid organ tumors (melanoma...
Phase 1
San Antonio, Texas, United States and 11 other locations
This Phase 1/2, first-in-human, open-label, multicenter study follows a 3+3 ascending dose escalation design to determine the MTD/RP2D and to charact...
Phase 1, Phase 2
San Antonio, Texas, United States and 9 other locations
This study is an open-label, Phase 1, multicenter study to evaluate the safety, tolerability, PK, and PD profiles of AGEN2373 as a monotherapy and in...
Phase 1
San Antonio, Texas, United States and 11 other locations
A first-in-human, Phase I, open-label, multicenter study of WTX-124 administered as monotherapy and in combination with pembrolizumab to patients wit...
Phase 1
San Antonio, Texas, United States and 7 other locations
This is a Phase 1/2, first-in-human, open-label, dose escalation and dose-expansion study of E-602, administered alone and in combination with cemipl...
Phase 1, Phase 2
San Antonio, Texas, United States and 12 other locations
This is a Phase 1, FIH, Dose Escalation and Dose Expansion study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) e...
Phase 1
San Antonio, Texas, United States and 4 other locations
TTX-080-001 is a Phase 1, open label, dose escalation and dose expansion clinical study to determine the safety, tolerability, and recommended Phase...
Phase 1
San Antonio, Texas, United States and 38 other locations
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