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Find clinical trials for Melanoma in St Louis, MO

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Related conditions:

Non-Small-Cell Lung Carcinoma
Cancer
Neoplasm Metastasis
Squamous Cell Carcinoma of Head and Neck
Renal Cell Carcinoma
Colorectal Cancer
Uveal Melanoma

Melanoma trials near St Louis, MO, USA:

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

therapy per local standard of care \[SoC\], best supportive care \[BSC\] on protocol survivor follow up) in patients with advanced non-ocular melanoma...

Enrolling
Advanced Melanoma
Drug: Tebentafusp with Pembrolizumab
Drug: Tebentafusp

Phase 3

Immunocore
Immunocore

St Louis, Missouri, United States and 81 other locations

cell death protein-1 (PD-1) inhibitor, in patients with metastatic melanomas or advanced solid tumors. Our hypothesis is that restoration of...

Active, not recruiting
Mucosal Melanoma
Melanoma
Drug: Phase 1b: APG-115+pembrolizumab

Phase 1, Phase 2

Ascentage Pharma Group
Ascentage Pharma Group

St Louis, Missouri, United States and 20 other locations

and overall survival (OS) for patients with NRAS-mutant (NRASm) melanoma who are randomized to receive the combination of naporafenib + tram...

Active, not recruiting
Advanced or Metastatic NRAS-mutant Melanoma
Drug: Trametinib
Drug: Naporafenib

Phase 3

Erasca

St Louis, Missouri, United States and 58 other locations

The study is focused on patients with a type of skin cancer known as melanoma. The aim of the study is to see how safe and effective the com...

Enrolling
Melanoma
Drug: fianlimab
Drug: cemiplimab

Phase 3

Regeneron Pharmaceuticals
Regeneron Pharmaceuticals

St Louis, Missouri, United States and 112 other locations

sub-type 1 receptor (MC1R) is being evaluated as a monotherapy and in combination with nivolumab in subjects with unresectable and metastatic melanoma...

Enrolling
Melanoma Stage IV
Melanoma Stage III
Drug: Nivolumab
Drug: [212Pb]VMT01

Phase 1, Phase 2

Perspective Therapeutics

St Louis, Missouri, United States and 17 other locations

antigen (HLA)-A\*02:01 negative participants with metastatic uveal melanoma (MUM) who will be randomized to receive either IDE196 + crizotin...

Active, not recruiting
Metastatic Uveal Melanoma
Drug: IDE196
Drug: Nivolumab

Phase 2, Phase 3

Ideaya Biosciences

St Louis, Missouri, United States and 67 other locations

use the immune system to recognize and kill cancer cells. The study is focused on participants with a type of skin cancer known as melanoma...

Active, not recruiting
Melanoma
Drug: Placebo
Drug: cemiplimab

Phase 2

Regeneron Pharmaceuticals
Regeneron Pharmaceuticals

St Louis, Missouri, United States and 103 other locations

treatment of adult subjects with completely treated high-risk ocular melanoma, as defined in eligibility criteria, without evidence of metas...

Active, not recruiting
Melanoma
Ocular Melanoma
Drug: Ipilimumab
Drug: Nivolumab

Phase 2

Suthee Rapisuwon

Saint Louis, Missouri, United States and 5 other locations

combined with nivolumab in patients with unresectable or metastatic melanoma. A separate open-label cohort of adults with new, progressive b...

Active, not recruiting
Unresectable or Metastatic Melanoma
Progressive Brain Metastasis
Drug: Placebo in combination with nivolumab
Drug: HBI-8000 in combination with nivolumab

Phase 3

HUYABIO

Bridgeton, Missouri, United States and 138 other locations

and pembrolizumab improves recurrence free survival (RFS) compared to pembrolizumab alone in participants with complete resection of cutaneous melanoma...

Active, not recruiting
Melanoma
Drug: mRNA-4157
Biological: Pembrolizumab

Phase 2

Moderna
Moderna

St Louis, Missouri, United States and 22 other locations

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