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Find clinical trials for Multiple Myeloma in Boston, MA

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Multiple Myeloma trials near Boston, MA, USA:

A Phase 1 Study of Vaccination With Dendritic Cell (DC)/Multiple Myeloma (MM) Fusions in Combination With Elranatamab in Relapsed or Refractory Multiple Myeloma

This research is being done to determine if the combination of the Dendritic Cell (DC)/ Multiple Myeloma (MM) fusion vaccine with e ...

Enrolling
Relapse Multiple Myeloma
Multiple Myeloma
Biological: DC/MM Fusion Vaccine
Drug: Elranatamab

Phase 1

David Avigan

Boston, Massachusetts, United States and 1 other location

if the study drug, elranatamab, reduces the risk of disease progression (worsening disease) after idecabtagene vicleucel in relapsed refractory multiple...

Enrolling
Multiple Myeloma
Relapse Multiple Myeloma
Drug: Elranatamab

Phase 2

Mass General Brigham
Mass General Brigham

Boston, Massachusetts, United States and 2 other locations

This research study is studying a combination of study drugs as a possible treatment for relapsed and refractory Multiple Myeloma. ...

Active, not recruiting
Multiple Myeloma
Drug: Dexamethasone
Drug: Elotuzumab

Phase 2

Mass General Brigham
Mass General Brigham

Boston, Massachusetts, United States and 5 other locations

This research study is studying a targeted therapy as a possible treatment for multiple myeloma.The names of the study drugs involv...

Active, not recruiting
Multiple Myeloma
Drug: Trametinib
Drug: Dabrafenib

Phase 1

Mass General Brigham
Mass General Brigham

Boston, Massachusetts, United States and 1 other location

pomalidomide, and dexamethasone in relapsed and refractory multiple myeloma. The study drugs provided for research purposes are isa...

Enrolling
Multiple Myeloma
Refractory Multiple Myeloma
Drug: Pomalidomide
Drug: Isatuximab

Phase 2

Mass General Brigham
Mass General Brigham

Boston, Massachusetts, United States and 1 other location

This research study is studying a drug as a possible treatment for Monoclonal Gammopathy of Unknown Significance (MGUS) or Smoldering Multiple...

Active, not recruiting
Smoldering Multiple Myeloma
Monoclonal Gammopathy
Drug: Daratumumab

Phase 2

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Boston, Massachusetts, United States and 5 other locations

The purpose of this study is to evaluate the safety and preliminary efficacy of CC-92480 in combination with standard treatments.

Active, not recruiting
Multiple Myeloma
Drug: Isatuximab
Drug: CC-92480

Phase 1, Phase 2

Celgene
Celgene

Boston, Massachusetts, United States and 48 other locations

the combination of daratumumab, lenalidomide, bortezomib, dexamethasone for patients with newly diagnosed, transplant ineligible/deferred multiple...

Begins enrollment this month
Multiple Myeloma
Newly Diagnosed Multiple Myeloma
Drug: Bortezomib for Injection
Drug: Dexamethasone

Phase 2

Mass General Brigham
Mass General Brigham

Boston, Massachusetts, United States and 2 other locations

The purpose of this study is to evaluate the safety and tolerability of mRNA-2808 in participants with relapsed or refractory multiple myeloma...

Enrolling
Relapsed or Refractory Multiple Myeloma
Drug: mRNA-2808

Phase 1, Phase 2

Moderna
Moderna

Boston, Massachusetts, United States of America and 9 other locations

and dexamethasone combination in patients with newly diagnosed multiple myeloma. We are looking for the highest dose of the combina...

Active, not recruiting
Multiple Myeloma
Drug: dexamethasone
Drug: Bortezomib

Phase 1, Phase 2

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Boston, Massachusetts, United States and 2 other locations

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