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Find clinical trials for Multiple Myeloma in Cleveland, OH

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Lymphoma
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Multiple Myeloma trials near Cleveland, OH, USA:

A Modular, Phase I/II, Multicentre Study to Evaluate AZD4045, in Participants With Relapsed or Refractory Multiple Myeloma

The purpose of this study is to assess the safety, tolerability, preliminary efficacy, cellular kinetics, and other exploratory endpoints of AZD4045...

Not yet enrolling
Relapsed or Refractory Multiple Myeloma
Drug: Aldesleukin
Biological: AZD4045

Phase 1, Phase 2

AstraZeneca
AstraZeneca

Cleveland, Ohio, United States and 11 other locations

versus Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) followed by Autologous Stem Cell Transplant (ASCT) in newly diagnosed multiple...

Active, not recruiting
Multiple Myeloma
Drug: Fludarabine
Drug: Lenalidomide

Phase 3

Stichting European Myeloma Network

Cleveland, Ohio, United States and 107 other locations

of CB-011, and to assess the effectiveness of CB-011 in treating multiple myeloma that has come back (relapsed) or that is no longe...

Enrolling
Relapsed/Refractory Multiple Myeloma
Biological: CB-011

Phase 1

Caribou Biosciences

Cleveland, Ohio, United States and 15 other locations

monotherapy (control) in participants with newly diagnosed multiple myeloma after undergoing autologous stem cell transplant. In Pa...

Active, not recruiting
Multiple Myeloma
Drug: Lenalidomide
Drug: Elranatamab

Phase 3

Pfizer
Pfizer

Cleveland, Ohio, United States and 211 other locations

in combination with pomalidomide and dexamethasone, in patients with multiple myeloma that has come back following treatment and wh...

Enrolling
Multiple Myeloma in Relapse
Multiple Myeloma Refractory
Drug: Inobrodib
Drug: Dexamethasone

Phase 2

CellCentric

Cleveland, Ohio, United States and 19 other locations

Relapsed Refractory Multiple Myeloma and CC-220 in combination with DEX and BTZ for Newly Diagnosed Multiple Myeloma...

Active, not recruiting
Multiple Myeloma
Drug: CC-220
Drug: Bortezomib (BTZ)

Phase 1, Phase 2

Celgene
Celgene

Cleveland, Ohio, United States and 161 other locations

with dexamethasone and daratumumab (IberDd) versus daratumumab, bortezomib, and dexamethasone (DVd) in participants with relapsed or refractory multiple...

Active, not recruiting
Multiple Myeloma
Drug: Bortezomib
Drug: Dexamethasone

Phase 3

Celgene
Celgene

Cleveland, Ohio, United States and 265 other locations

Multiple myeloma (MM) is a cancer of the blood's plasma cells. The cancer is typically found in the bones and bone marrow (the spon...

Enrolling
Multiple Myeloma
Drug: Carfilzomib
Drug: Etentamig

Phase 3

AbbVie
AbbVie

Cleveland, Ohio, United States and 165 other locations

A study designed tocompare progression-free survival (PFS) in participants with t(11;14)-positive MM treated with venetoclax in combination with dexa...

Active, not recruiting
Multiple Myeloma
Drug: Pomalidomide
Drug: Venetoclax

Phase 3

AbbVie
AbbVie

Cleveland, Ohio, United States and 182 other locations

in combination with Pd/DRd in patients with relapsed/refractory (RR) multiple myeloma (MM). The study consists of dose escalation a...

Enrolling
Multiple Myeloma
Amyloidosis
Drug: APG-2575 + DRd
Drug: APG-2575+ Pd

Phase 1, Phase 2

Ascentage Pharma Group
Ascentage Pharma Group

Cleveland, Ohio, United States and 2 other locations

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