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Find clinical trials for Multiple Myeloma in Detroit, MI

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Multiple Myeloma trials near Detroit, MI, USA:

A Study of Elotuzumab With Pomalidomide, Bortezomib, and Dexamethasone in Relapsed Multiple Myeloma

This research study is studying a combination of study drugs as a possible treatment for relapsed and refractory Multiple Myeloma. ...

Active, not recruiting
Multiple Myeloma
Drug: Dexamethasone
Drug: Elotuzumab

Phase 2

Mass General Brigham
Mass General Brigham

Ann Arbor, Michigan, United States and 5 other locations

This research study is studying a targeted therapy as a possible treatment for multiple myeloma.The names of the study drugs involv...

Active, not recruiting
Multiple Myeloma
Drug: Trametinib
Drug: Dabrafenib

Phase 1

Mass General Brigham
Mass General Brigham

Detroit, Michigan, United States and 1 other location

This research study is studying a drug as a possible treatment for Monoclonal Gammopathy of Unknown Significance (MGUS) or Smoldering Multiple...

Active, not recruiting
Smoldering Multiple Myeloma
Monoclonal Gammopathy
Drug: Daratumumab

Phase 2

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Detroit, Michigan, United States and 5 other locations

The purpose of this study is to evaluate the safety and preliminary efficacy of CC-92480 in combination with standard treatments.

Active, not recruiting
Multiple Myeloma
Drug: Isatuximab
Drug: CC-92480

Phase 1, Phase 2

Celgene
Celgene

Detroit, Michigan, United States and 48 other locations

is a Phase 1b/2, open-label, multicenter study of AZD0120, a CD19/BCMA dual CAR T-cell therapy, in adult subjects with relapsed/refractory multiple...

Enrolling
Relapsed/Refractory Multiple Myeloma
Biological: AZD0120

Phase 1, Phase 2

AstraZeneca
AstraZeneca

Detroit, Michigan, United States and 35 other locations

The purpose of this research study is to evaluate a treatment regimen called IRD which will be given to participants after their stem cell transplant...

Active, not recruiting
Multiple Myeloma
Biological: Ixazomib
Drug: Dexamethasone

Phase 2

The Washington University
The Washington University

Detroit, Michigan, United States and 9 other locations

versus Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) followed by Autologous Stem Cell Transplant (ASCT) in newly diagnosed multiple...

Active, not recruiting
Multiple Myeloma
Drug: Fludarabine
Drug: Lenalidomide

Phase 3

Stichting European Myeloma Network

Detroit, Michigan, United States and 107 other locations

Multiple myeloma (MM) is a cancer of the blood's plasma cells. The cancer is typically found in the bones and bone marrow (the spon...

Active, not recruiting
Multiple Myeloma
Drug: Intravenous (IV) Etentamig
Drug: Subcutaneous (SC) Etentamig

Phase 1

AbbVie
AbbVie

Ann Arbor, Michigan, United States and 14 other locations

This is a post-trial access (PTA) open-label, single-arm study in Multiple Myeloma participants who continue to derive clinical ben...

Enrolling
Multiple Myeloma
Drug: Elranatamab

Phase 4

Pfizer
Pfizer

Detroit, Michigan, United States and 33 other locations

This is a Phase I/II, modular, open-label, multicenter, dose escalation, and dose expansion/optimization study to evaluate the safety, tolerability,...

Enrolling
Multiple Myeloma
Drug: Pomalidomide
Drug: AZD0305

Phase 1, Phase 2

AstraZeneca
AstraZeneca

Ann Arbor, Michigan, United States and 39 other locations

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