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lenalidomide and dexamethasone for the treatment of newly diagnosed multiple myeloma (MM). The study team will use lower doses than...
Phase 2
Durham, North Carolina, United States and 2 other locations
This study is designed as a phase I-II, open label, dose finding study.Study treatment will be as follows, in 28 day cycles:* Pomalidomide: once dail...
Phase 1, Phase 2
Durham, North Carolina, United States
of these combinations in participants with relapsed or refractory multiple myeloma. The study will consist of 3 distinct parts: Par ...
Phase 2
Durham, North Carolina, United States and 40 other locations
A Phase 2, open-label, dose escalation study to evaluate the safety and efficacy of venetoclax in combination with carfilzomib-dexamethasone (Kd) in...
Phase 2
Durham, North Carolina, United States and 31 other locations
versus standard regimens in subjects with relapsed and refractory multiple myeloma (RRMM).The study is anticipated to randomize app...
Phase 3
Durham, North Carolina, United States and 59 other locations
phases, for the treatment of patients with relapsed/refractory multiple myeloma (RRMM) and newly diagnosed multiple myeloma...
Phase 1, Phase 2
Durham, North Carolina, United States and 24 other locations
This study is a first-in-human, Phase 1, open-label study that will evaluate safety and anti-myeloma activity of ISB 2001 in participants wi ...
Phase 1
Chapel Hill, North Carolina, United States and 6 other locations
This is a phase 1, open-label study evaluating the safety, clinical pharmacology and clinical activity of TNB-383B, a BCMA x CD3 T-cell engaging bisp...
Phase 1, Phase 2
Chapel Hill, North Carolina, United States and 13 other locations
versus Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) followed by Autologous Stem Cell Transplant (ASCT) in newly diagnosed multiple...
Phase 3
Durham, North Carolina, United States and 126 other locations
Multiple Myeloma (MM) is a cancer of the blood's plasma cells ( blood cell). The cancer is typically found in the bones and bone ma...
Phase 1
Chapel Hill, North Carolina, United States and 32 other locations
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