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The purpose of this study is to evaluate three daratumumab dose schedules in participants with Smoldering Multiple Myeloma....
Phase 2
Chapel Hill, North Carolina, United States and 56 other locations
lenalidomide and dexamethasone for the treatment of newly diagnosed multiple myeloma (MM). The study team will use lower doses than...
Phase 2
Durham, North Carolina, United States and 2 other locations
This study is designed as a phase I-II, open label, dose finding study.Study treatment will be as follows, in 28 day cycles:Pomalidomide: once daily...
Phase 1, Phase 2
Durham, North Carolina, United States
of these combinations in participants with relapsed or refractory multiple myeloma. The study will consist of 3 distinct parts: Par ...
Phase 2
Durham, North Carolina, United States and 39 other locations
A Phase 2, open-label, dose escalation study to evaluate the safety and efficacy of venetoclax in combination with carfilzomib-dexamethasone (Kd) in...
Phase 2
Durham, North Carolina, United States and 31 other locations
phases, for the treatment of patients with relapsed/refractory multiple myeloma (RRMM) and newly diagnosed multiple myeloma...
Phase 1, Phase 2
Durham, North Carolina, United States and 18 other locations
versus standard regimens in subjects with relapsed and refractory multiple myeloma (RRMM).The study is anticipated to randomize app...
Phase 3
Durham, North Carolina, United States and 59 other locations
This is a phase 1, open-label study evaluating the safety, clinical pharmacology and clinical activity of TNB-383B, a BCMA x CD3 T-cell engaging bisp...
Phase 1, Phase 2
Chapel Hill, North Carolina, United States and 13 other locations
The purpose of this study is to evaluate the effectiveness and safety of BMS-986393 in participants with relapsed or refractory multiple myeloma...
Phase 2
Chapel Hill, North Carolina, United States and 35 other locations
Multiple Myeloma (MM) is a cancer of the blood's plasma cells ( blood cell). The cancer is typically found in the bones and bone ma...
Phase 1
Chapel Hill, North Carolina, United States and 27 other locations
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