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Find clinical trials for Multiple Myeloma in St Louis, MO

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Related conditions:

Plasma Cell Cancer
Lymphoma
Hematologic Cancer
Cancer
Leukemia
Smoldering Multiple Myeloma
Non-Hodgkin Lymphoma

Multiple Myeloma trials near St Louis, MO, USA:

A Study of ION251 Administered to Patients With Relapsed/Refractory Multiple Myeloma

this study is to determine the maximum-tolerated dose (MTD) and recommended Phase 2 dose (RP2D) of ION251 in patients with relapsed/refractory multiple...

Active, not recruiting
Refractory Multiple Myeloma
Relapsed Multiple Myeloma
Drug: ION251

Phase 1

Ionis Pharmaceuticals
Ionis Pharmaceuticals

Saint Louis, Missouri, United States and 5 other locations

The purpose of this study is to evaluate three daratumumab dose schedules in participants with Smoldering Multiple Myeloma....

Active, not recruiting
Multiple Myeloma
Drug: daratumumab

Phase 2

Janssen (J&J Innovative Medicine)

Saint Louis, Missouri, United States and 56 other locations

and safety of bb2121 in participants with relapsed and refractory multiple myeloma (RRMM) (Cohort 1), in participants with RRMM who ...

Enrolling
Multiple Myeloma
Biological: bb2121
Drug: Talquetamab

Phase 2

Celgene
Celgene

Saint Louis, Missouri, United States and 25 other locations

This phase II clinical trial studies the addition of selinexor to lenalidomide in patients with multiple myeloma following transpla ...

Enrolling
Multiple Myeloma
Myeloma-Associated Amyloidosis
Drug: Lenalidomide
Drug: Selinexor

Phase 2

The Washington University
The Washington University

Saint Louis, Missouri, United States

This is a Phase I dose-finding study of FT576 as monotherapy and in combination with the monoclonal antibody daratumumab in multiple myeloma...

Enrolling
Multiple Myeloma
Myeloma
Drug: Bendamustine
Drug: FT576 (Allogenic CAR NK cells with BCMA expression)

Phase 1

Fate Therapeutics
Fate Therapeutics

Saint Louis, Missouri, United States and 13 other locations

A Phase 2, open-label, dose escalation study to evaluate the safety and efficacy of venetoclax in combination with carfilzomib-dexamethasone (Kd) in...

Active, not recruiting
Multiple Myeloma
Drug: Venetoclax
Drug: Dexamethasone

Phase 2

AbbVie
AbbVie

Saint Louis, Missouri, United States and 31 other locations

The purpose of this research study is to evaluate a treatment regimen called IRD which will be given to participants after their stem cell transplant...

Active, not recruiting
Multiple Myeloma
Biological: Ixazomib
Drug: Dexamethasone

Phase 2

The Washington University
The Washington University

Saint Louis, Missouri, United States and 9 other locations

versus standard regimens in subjects with relapsed and refractory multiple myeloma (RRMM).The study is anticipated to randomize app...

Active, not recruiting
Multiple Myeloma
Drug: Dexamethasone
Drug: Carfilzomib

Phase 3

Celgene
Celgene

Saint Louis, Missouri, United States and 59 other locations

This is a phase 1, open-label study evaluating the safety, clinical pharmacology and clinical activity of TNB-383B, a BCMA x CD3 T-cell engaging bisp...

Active, not recruiting
Multiple Myeloma
Drug: TNB-383B

Phase 1, Phase 2

TeneoOne

Saint Louis, Missouri, United States and 13 other locations

progression-free survival (PFS) in participants with newly diagnosed multiple myeloma (a blood cancer of plasma cells) who are not ...

Active, not recruiting
Multiple Myeloma
Drug: Daratumumab SC
Drug: Daratumumab IV

Phase 3

Janssen (J&J Innovative Medicine)

Saint Louis, Missouri, United States and 211 other locations

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