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Find clinical trials for Multiple Myeloma in St Louis, MO

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Plasma Cell Cancer
Recurrence
Cancer
Hematologic Cancer
Lymphoma
Non-Hodgkin Lymphoma
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Multiple Myeloma trials near St Louis, MO, USA:

An Efficacy and Safety Study of bb2121 in Subjects With Relapsed and Refractory Multiple Myeloma and in Subjects With High-Risk Multiple Myeloma (KarMMa-2)

and safety of bb2121 in participants with relapsed and refractory multiple myeloma (RRMM) (Cohort 1), in participants with RRMM who ...

Active, not recruiting
Multiple Myeloma
Biological: bb2121
Drug: Talquetamab

Phase 2

Celgene
Celgene

Saint Louis, Missouri, United States and 24 other locations

The outcomes in patients with relapsed multiple myeloma refractory to triple-therapy (anti-CD38, immunomodulatory drugs (IMiD) and ...

Not yet enrolling
Multiple Myeloma
Drug: Selinexor

Phase 1

The Washington University
The Washington University

St Louis, Missouri, United States

The purpose of this research study is to evaluate a treatment regimen called IRD which will be given to participants after their stem cell transplant...

Active, not recruiting
Multiple Myeloma
Biological: Ixazomib
Drug: Dexamethasone

Phase 2

The Washington University
The Washington University

St Louis, Missouri, United States and 9 other locations

A Phase 2, open-label, dose escalation study to evaluate the safety and efficacy of venetoclax in combination with carfilzomib-dexamethasone (Kd) in...

Active, not recruiting
Multiple Myeloma
Drug: Venetoclax
Drug: Carfilzomib

Phase 2

AbbVie
AbbVie

Saint Louis, Missouri, United States and 31 other locations

interventional, modular, open-label, multicenter study to primarily evaluate the safety and tolerability of AZD0120 in adult participants with multiple...

Enrolling
Multiple Myeloma
Biological: AZD0120

Phase 1

AstraZeneca
AstraZeneca

St Louis, Missouri, United States and 8 other locations

versus standard regimens in subjects with relapsed and refractory multiple myeloma (RRMM).The study is anticipated to randomize app...

Active, not recruiting
Multiple Myeloma
Biological: bb2121
Drug: Dexamethasone

Phase 3

Celgene
Celgene

Saint Louis, Missouri, United States and 59 other locations

This is a phase 1, open-label study evaluating the safety, clinical pharmacology and clinical activity of TNB-383B, a BCMA x CD3 T-cell engaging bisp...

Active, not recruiting
Multiple Myeloma
Drug: TNB-383B

Phase 1, Phase 2

TeneoOne

Saint Louis, Missouri, United States and 13 other locations

of this study is to evaluate the effectiveness and safety of Arlocabtagene Autoleucel (BMS-986393) in participants with relapsed or refractory multiple...

Enrolling
Multiple Myeloma
Biological: Arlocabtagene Autoleucel

Phase 2

Juno Therapeutics

St Louis, Missouri, United States and 51 other locations

with Relapsed/Refractory (r/r) Non-Hodgkin's Lymphoma (NHL) or Multiple Myeloma (MM). Cemsidomide may be administered as a single a...

Active, not recruiting
Multiple Myeloma
Lymphoma, Non-Hodgkin's
Drug: Dexamethasone Oral
Drug: cemsidomide

Phase 1

C4 Therapeutics

St Louis, Missouri, United States and 12 other locations

This is a Phase I/II, modular, open-label, multicenter, dose escalation, and dose expansion/optimization study to evaluate the safety, tolerability,...

Enrolling
Multiple Myeloma
Drug: AZD0305

Phase 1, Phase 2

AstraZeneca
AstraZeneca

St Louis, Missouri, United States and 32 other locations

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