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Find clinical trials for Multiple Sclerosis (MS) in London, England

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Related conditions:

Sclerosis
Multiple Sclerosis
Relapsing-Remitting Multiple Sclerosis
Chronic Progressive Multiple Sclerosis
Amyotrophic Lateral Sclerosis
Motor Neuron Disease
Muscle Spasticity

Multiple Sclerosis (MS) trials near London, England, GBR:

Efficacy and Safety of Ofatumumab and Siponimod Compared to Fingolimod in Pediatric Patients With Multiple Sclerosis (NEOS)

Efficacy and safety of ofatumumab and siponimod compared to fingolimod in pediatric patients with multiple sclerosis...

Enrolling
Multiple Sclerosis (MS)
Drug: Siponimod
Drug: Ofatumumab

Phase 3

Novartis
Novartis

London, United Kingdom and 72 other locations

SIZOMUS Safety of Ixazomib Targeting Plasma Cells in Multiple Sclerosis

The study seeks to investigate safety and efficacy of ixazomib (NINLARO), a proteasome inhibitor, in multiple sclerosis (MS...

Enrolling
Primary Progressive Multiple Sclerosis
Secondary Progressive Multiple Sclerosis
Drug: Ixazomib (NINLARO®) capsules / Matching placebo capsules

Phase 1

Queen Mary University of London

London, Greater London, United Kingdom

This is an Extension Study of the Roche P-trials to Investigate Safety and Effectiveness of Ocrelizumab in Participants With Multiple Sclerosis (MS)

This extension study will evaluate the effectiveness and safety of ocrelizumab in multiple sclerosis (MS) participants who...

Active, not recruiting
Multiple Sclerosis
Drug: Ocrelizumab

Phase 3

Roche
Roche

London, United Kingdom and 161 other locations

Safety and Efficacy of Fingolimod in Pediatric Patients With Multiple Sclerosis

To evaluate the safety and efficacy of fingolimod vs. interferon beta-1a i.m. in pediatric patients with multiple sclerosis (MS...

Enrolling
Multiple Sclerosis
Drug: Placebo capsule
Drug: Fingolimod

Phase 3

Novartis
Novartis

London, United Kingdom and 107 other locations

A Study Evaluating B Cell Levels In Infants Of Lactating Women With CIS Or MS Receiving Ocrelizumab (SOPRANINO)

This study will evaluate the pharmacokinetics of ocrelizumab in the breastmilk of lactating women with clinically isolated syndrome (CIS) or multiple...

Active, not recruiting
Multiple Sclerosis
Clinically Isolated Syndrome
Drug: Ocrelizumab

Phase 4

Roche
Roche

London, United Kingdom and 9 other locations

A Study to Evaluate Efficacy, Safety, and Tolerability of Alemtuzumab in Pediatric Patients With RRMS With Disease Activity on Prior DMT (LemKids)

effects of alemtuzumab on other multiple sclerosis (MS) disease characteristics such as cognition and quality of life (Qo...

Active, not recruiting
Multiple Sclerosis
Drug: Beta-Interferon
Drug: Methylprednisolone

Phase 3

Genzyme
Genzyme

London, London, City Of, United Kingdom and 20 other locations

Natalizumab for the Treatment of People With Inflammatory Demyelination Suggestive of Multiple Sclerosis, or Definite Multiple Sclerosis, at First Presentation (AttackMS)

Multiple Sclerosis (MS) is a chronic inflammatory & degenerative disease of the central nervous system (CNS) Recent data f...

Enrolling
Multiple Sclerosis
Clinically Isolated Syndrome of Demyelination
Drug: Tysabri Injectable Product
Drug: Placebo

Phase 2

Queen Mary University of London

London, United Kingdom

Efficacy, Safety and Pharmacokinetics of Teriflunomide in Pediatric Patients With Relapsing Forms of Multiple Sclerosis (TERIKIDS)

and adolescents 10 to 17 years of age with relapsing forms of multiple sclerosis (MS).Secondary Objective:To assess the ef...

Active, not recruiting
Multiple Sclerosis
Drug: Placebo
Drug: Teriflunomide

Phase 3

Genzyme
Genzyme

London, London, City Of, United Kingdom and 54 other locations

A Study To Evaluate Safety And Efficacy Of Ocrelizumab In Comparison With Fingolimod In Children And Adolescents With Relapsing-Remitting Multiple Sclerosis (Operetta 2)

with fingolimod in children and adolescents with relapsing-remitting multiple sclerosis aged between 10 and < 18 years over a durat...

Enrolling
Relapsing-Remitting Multiple Sclerosis
Other: Ocrelizumab Placebo
Other: Fingolimod Placebo

Phase 3

Roche
Roche

London, United Kingdom and 118 other locations

ChariotMS - Cladribine to Halt Deterioration in People With Advanced Multiple Sclerosis

effective and CNS penetrant DMT for patients with relapsing multiple sclerosis (pwRMS) administered in short (8-10 days/year over ...

Enrolling
Advanced Multiple Sclerosis
Progressive Multiple Sclerosis
Drug: Cladribine (MAVENCLAD®)
Drug: Placebo

Phase 2, Phase 3

Queen Mary University of London

London, United Kingdom and 21 other locations

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