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Find clinical trials for Multiple Sclerosis (MS) in Philadelphia, PA

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Related conditions:

Sclerosis
Multiple Sclerosis
Relapsing-Remitting Multiple Sclerosis
Chronic Progressive Multiple Sclerosis
Amyotrophic Lateral Sclerosis
Motor Neuron Disease
Muscle Spasticity

Multiple Sclerosis (MS) trials near Philadelphia, PA, USA:

Immune Profiles in Multiple Sclerosis (MS) Patients and Healthy Volunteers Through Thoracic Duct Cannulation

between immune cells in the periphery and deep lymphatic system in MS and healthy controls and in MS, changes in responses to a FDA...

Invitation-only
Multiple Sclerosis
Healthy
Procedure: thoracic duct cannulation
University of Pennsylvania
University of Pennsylvania

Philadelphia, Pennsylvania, United States

A safety study of ANK-700 in patients with relapsing remitting multiple sclerosis. The study has two parts:Part A - first in human ...

Active, not recruiting
Multiple Sclerosis (MS)
Relapsing Remitting Multiple Sclerosis
Drug: Placebo
Drug: ANK-700

Phase 1

Anokion

Philadelphia, Pennsylvania, United States and 14 other locations

of Best Available Therapy (BAT) for treatment-resistant relapsing multiple sclerosis (MS). Participants will be randomized...

Enrolling
Secondary Progressive Multiple Sclerosis
Relapsing Multiple Sclerosis
Procedure: Autologous Hematopoietic Stem Cell Transplantation
Biological: Best Available Therapy (BAT)

Phase 3

National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Allergy and Infectious Diseases (NIAID)

Philadelphia, Pennsylvania, United States and 18 other locations

Efficacy and safety of ofatumumab and siponimod compared to fingolimod in pediatric patients with multiple sclerosis...

Enrolling
Multiple Sclerosis (MS)
Other: Ofatumumab placebo
Drug: Siponimod

Phase 3

Novartis
Novartis

Philadelphia, Pennsylvania, United States and 73 other locations

will evaluate the pharmacokinetics, safety and tolerability, and immunogenicity of ocrelizumab administered subcutaneously to participants with multiple...

Active, not recruiting
Multiple Sclerosis (MS)
Drug: Ocrelizumab
Drug: rHuPH20

Phase 1

Roche
Roche

Philadelphia, Pennsylvania, United States and 20 other locations

To evaluate the safety and efficacy of fingolimod vs. interferon beta-1a i.m. in pediatric patients with multiple sclerosis (MS...

Enrolling
Multiple Sclerosis
Drug: Interferon beta-1a
Drug: Placebo capsule

Phase 3

Novartis
Novartis

Philadelphia, Pennsylvania, United States and 107 other locations

This study will evaluate the pharmacokinetics of ocrelizumab in the breastmilk of lactating women with clinically isolated syndrome (CIS) or multiple...

Enrolling
Multiple Sclerosis
Clinically Isolated Syndrome
Drug: Ocrelizumab

Phase 4

Roche
Roche

Philadelphia, Pennsylvania, United States and 9 other locations

This study will evaluate the potential placental transfer of ocrelizumab in women with clinically isolated syndrome (CIS) or multiple sclerosis...

Active, not recruiting
Multiple Sclerosis
Clinically Isolated Syndrome
Drug: Ocrelizumab

Phase 4

Roche
Roche

Philadelphia, Pennsylvania, United States and 10 other locations

with fingolimod in children and adolescents with relapsing-remitting multiple sclerosis aged between 10 and \< 18 years over a dura...

Enrolling
Relapsing-Remitting Multiple Sclerosis
Other: Ocrelizumab Placebo
Drug: Ocrelizumab

Phase 3

Roche
Roche

Philadelphia, Pennsylvania, United States and 120 other locations

This study will examine the effectiveness of a neuromyelitis optics spectrum disorder (NMOSD) specific Acceptance and Commitment Therapy (ACT) interv...

Enrolling
NMO Spectrum Disorder
Behavioral: Acceptance and Commitment Therapy
Thomas Jefferson University
Thomas Jefferson University

Philadelphia, Pennsylvania, United States

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