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of Best Available Therapy (BAT) for treatment-resistant relapsing multiple sclerosis (MS). Participants will be randomized...
Phase 3
St Louis, Missouri, United States and 21 other locations
The goal of this clinical trial is to treat male and female participants with two types of Multiple Sclerosis (MS) called ...
Phase 1, Phase 2
St Louis, Missouri, United States and 1 other location
This study aims to examine the efficacy and safety of obexelimab in participants with relapsing multiple sclerosis...
Phase 2
St Louis, Missouri, United States and 46 other locations
The primary objective of this trial is to evaluate the safety and reactogenicity of mRNA-1195 in participants with multiple sclerosis...
Phase 2
St Louis, Missouri, United States and 16 other locations
This double-blind, double-dummy study will evaluate the safety and efficacy of ocrelizumab compared with fingolimod in children and adolescents with...
Phase 3
St Louis, Missouri, United States and 102 other locations
clinical study of AZD0120, a BCMA/CD19 dual targeting CAR+ T-cell therapy, to evaluate the safety and tolerability in adult participants with Multiple...
Phase 1
St Louis, Missouri, United States and 12 other locations
To compare the efficacy and safety of remibrutinib versus teriflunomide in patients with relapsing multiple sclerosis (RMS)...
Phase 3
St Louis, Missouri, United States and 201 other locations
of remibrutinib after switching from ocrelizumab and compared to continuous ocrelizumab treatment, in patients living with relapsing multiple...
Phase 3
St Louis, Missouri, United States and 85 other locations
) neo-antigen in subjects with relapsing multiple sclerosis (RMS).COVID-19 sub-study:The purpose of this research sub-study is to e...
Phase 3
St Louis, Missouri, United States and 298 other locations
This is a Phase 3 extension, global, multicenter study to assess the long-term safety and tolerability of tolebrutinib in adult participants (aged ≥1...
Phase 3
St Louis, Missouri, United States and 352 other locations
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