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Find clinical trials for Non-Hodgkin Lymphoma in Durham, NC

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Related conditions:

Lymphoma
B-Cell Lymphoma
Diffuse Large B-Cell Lymphoma
Leukemia
Lymphoid Leukemia
B-Cell Chronic Lymphocytic Leukemia
Cancer

Non-Hodgkin Lymphoma trials near Durham, NC, USA:

A Study of TAK-007 in Adults With Relapsed or Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)

This study has 2 parts.The main aim of Part 1 is to check for side effects from TAK-007 in adults with relapsed or refractory (r/r) B-cell Non...

Active, not recruiting
Relapsed or Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)
Drug: Chemotherapy Agents
Biological: TAK-007

Phase 2

Takeda
Takeda

Durham, North Carolina, United States and 14 other locations

This is a Phase 1/1b, nonrandomized, open-label, parallel assignment, dose-escalation, and dose-expansion study to evaluate the safety and clinical a...

Enrolling
Non-Hodgkin Lymphoma
B-cell Acute Lymphoblastic Leukemia
Drug: Cyclophosphamide
Drug: Fludarabine

Phase 1

Imugene

Durham, North Carolina, United States and 20 other locations

evaluate the efficacy, safety, and tolerability BGB-3111 plus obinutuzumab versus obinutuzumab alone in participants with relapsed/refractory non...

Active, not recruiting
Relapsed/Refractory Follicular Non-Hodgkin Lymphoma
Drug: Zanubrutinib
Drug: Obinutuzumab

Phase 2

BeiGene
BeiGene

Durham, North Carolina, United States and 83 other locations

This is an open-label, multi-center Phase 1/2 study of oral LOXO-305 (pirtobrutinib) in patients with CLL/SLL and NHL who have failed or are intolera...

Active, not recruiting
Marginal Zone Lymphoma
Small Lymphocytic Lymphoma
Drug: Venetoclax
Drug: Rituximab

Phase 1, Phase 2

Loxo Oncology
Loxo Oncology

Durham, North Carolina, United States and 55 other locations

DS-3201b is an experimental drug that is being investigated in clinical research.Adults with non-Hodgkin lymphoma (NHL) ma...

Active, not recruiting
Lymphoma, Malignant
Non-hodgkin Lymphoma
Drug: DS-3201b

Phase 1

Daiichi Sankyo
Daiichi Sankyo

Durham, North Carolina, United States and 20 other locations

is focused on participants with previously untreated follicular lymphoma (a type of non-Hodgkin lymphoma or NHL)....

Enrolling
Follicular Lymphoma (FL)
Drug: Odronextamab
Drug: Rituximab

Phase 3

Regeneron Pharmaceuticals
Regeneron Pharmaceuticals

Chapel Hill, North Carolina, United States and 138 other locations

The study is focused on patients with diffuse large B-cell lymphoma (DLBCL) that have not been treated before (called "previously untreated"...

Enrolling
Diffuse Large B-cell Lymphoma (DLBCL)
Drug: Doxorubicin
Drug: Prednisone/Prednisolone

Phase 3

Regeneron Pharmaceuticals
Regeneron Pharmaceuticals

Durham, North Carolina, United States and 145 other locations

safety, and pharmacokinetics of zamtocabtagene autoleucel (MB-CART2019.1) in patients with relapsed and/or refractory diffuse large B cell lymphoma...

Enrolling
High Grade B-cell Lymphoma (HGBCL)
Refractory Diffuse Large B Cell Lymphoma (DLBCL)
Drug: Fludarabine
Drug: Cyclophosphamide

Phase 2

Miltenyi Biotec
Miltenyi Biotec

Durham, North Carolina, United States and 22 other locations

The study evaluates CLR 131 in children, adolescents, and young adults with relapsed or refractory malignant solid tumors and lymphoma and r...

Active, not recruiting
Pediatric Lymphoma
Osteosarcoma
Drug: CLR 131

Phase 1

Cellectar Biosciences

Chapel Hill, North Carolina, United States and 7 other locations

This study aims to evaluate the safety, tolerability, pharmacodynamic, and pharmacokinetic (PK) of nemtabrutinib (formerly ARQ 531) tablets in select...

Active, not recruiting
Lymphoma, B-Cell
Marginal Zone Lymphoma
Drug: Nemtabrutinib

Phase 1, Phase 2

ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA)

Durham, North Carolina, United States and 9 other locations

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