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positive, recurrent platinum sensitive, high-grade epithelial ovarian, primary peritoneal, or fallopian tube cancer following 1 pri...
Phase 2
Atlanta, Georgia, United States and 70 other locations
Olaparib Monotherapy in Patients with BRCA Mutated Ovarian Cancer following First Line Platinum Based Chemotherapy....
Phase 3
Atlanta, Georgia, United States and 176 other locations
This study will assess the safety and efficacy of avutometinib (VS-6766) in combination with defactinib versus Investigator's choice of treatments (I...
Phase 3
Atlanta, Georgia, United States and 53 other locations
in combination with pembrolizumab versus protocol-specific Investigator's choice chemotherapy in patients with platinum-resistant epithelial ovarian...
Phase 3
Atlanta, Georgia, United States and 117 other locations
of sovilnesib at different dose levels to establish the Recommended Phase 2 Dose (RP2D) of sovilnesib in subjects with high grade serous ovarian...
Phase 1
Atlanta, Georgia, United States and 11 other locations
This study aims to assess efficacy of Niraparib (GSK3985771) as maintenance treatment in participants with Stage III or IV ovarian cancer...
Phase 3
Atlanta, Georgia, United States and 196 other locations
This is a Phase 2, multicenter, two-stage, open-label, parallel-group study designed to evaluate the efficacy and safety of vudalimab (XmAb20717) in...
Phase 2
Atlanta, Georgia, United States and 16 other locations
The purpose of this study is to look at the effectiveness, safety, and antitumor activity of study drugs MEDI4736 in combination with olaparib (modul...
Phase 1, Phase 2
Newnan, Georgia, United States and 46 other locations
following response to front-line treatment in newly diagnosed ovarian cancer patients. Response to treatment will be analyzed based...
Phase 3
Atlanta, Georgia, United States and 237 other locations
survival (PFS) per Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 as assessed by the investigator. The hypotheses are that pembro...
Phase 3
Marietta, Georgia, United States and 186 other locations
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