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efficacy with the combination of a next generation anti-CTLA-4 antibody, ONC-392, and anti-PD-1 antibody, pembrolizumab, in platinum resistant ovarian...
Phase 2
Austin, Texas, United States and 20 other locations
the safety and efficacy of avutometinib (VS-6766) monotherapy and in combination with defactinib in subjects with recurrent Low-Grade Serous Ovarian...
Phase 2
Austin, Texas, United States and 46 other locations
study is to compare how well Rina-S works against platinum-resistant ovarian cancer compared to chemotherapy drugs that are already ...
Phase 3
Austin, Texas, United States and 176 other locations
This study will assess the safety and efficacy of avutometinib (VS-6766) in combination with defactinib versus Investigator's choice of treatments (I...
Phase 3
Austin, Texas, United States and 105 other locations
This study will evaluate the safety and efficacy of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer (PROC) With C...
Phase 2
Austin, Texas, United States and 78 other locations
(ADC), in adult participants with advanced or metastatic solid tumors known to be expressing PTK7. The study employs a sequential dose escal...
Phase 1
Austin, Texas, United States and 11 other locations
Ovarian cancer is a heterogeneous disease, characterized by complex molecular and genetic changes. The high expression of vascular ...
Phase 3
Austin, Texas, United States and 181 other locations
Patients will be registered prior to, during or at the completion of neoadjuvant chemotherapy given per standard institutional guidelines +/- bevaciz...
Phase 3
Austin, Texas, United States and 57 other locations
Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. The purpose of this study is to assess the s...
Phase 2
Austin, Texas, United States and 49 other locations
This study will test the safety, including side effects, and determine the characteristics of a drug called Rina-S in participants with solid tumors...
Phase 1, Phase 2
Austin, Texas, United States and 66 other locations
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