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Find clinical trials for Ovarian Cancer in Birmingham, AL

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Related conditions:

Ovarian Epithelial Carcinoma
Endometrial Cancer
Cancer
Breast Cancer
Fallopian Tube Cancer
Non-Small-Cell Lung Carcinoma
Triple Negative Breast Cancer

Ovarian Cancer trials near Birmingham, AL, USA:

Newly Diagnosed Stage III/IV Ovarian Cancer, Neoadjuvant Carbo/taxol/pembro, Maintenance Olaparib/pembro

this is a trial evaluating three chemotherapy agents in patients with newly diagnosed ovarian cancer patients that are Stage III or...

Enrolling
Ovarian Cancer
Drug: olaparibp, embro
Drug: Carboplatin

Phase 2

The University of Alabama at Birmingham
The University of Alabama at Birmingham

Birmingham, Alabama, United States

Olaparib Treatment in BRCA Mutated Ovarian Cancer Patients After Complete or Partial Response to Platinum Chemotherapy

of olaparib maintenance monotherapy in relapsed high grade serous ovarian cancer (HGSOC) patients (including patients with primary ...

Active, not recruiting
Relapsed Ovarian Cancer
Following Complete or Partial Response to Platinum Based Chemotherapy
Drug: Placebo to match olaparib 300mg
Drug: Olaparib 300mg tablets

Phase 3

AstraZeneca
AstraZeneca

Birmingham, Alabama, United States and 126 other locations

Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

as "study drug". The study is focused on patients who have advanced ovarian cancer.The aim of the study is to see how safe, tolerab...

Enrolling
Ovarian Cancer
Drug: Bevacizumab
Drug: Sarilumab

Phase 2

Regeneron Pharmaceuticals
Regeneron Pharmaceuticals

Birmingham, Alabama, United States and 43 other locations

Study of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers

of ubamatamab can be given alone or with cemiplimab to patients with ovarian cancer or cancer of the uterus* The study wil...

Enrolling
Endometrial Cancer
Recurrent Primary Peritoneal Cancer
Drug: Sarilumab
Drug: Ubamatamab

Phase 1, Phase 2

Regeneron Pharmaceuticals
Regeneron Pharmaceuticals

Birmingham, Alabama, United States and 52 other locations

Study of IMNN-001 (Also Known as GEN-1) With NACT for Treatment of Ovarian Cancer (OVATION 2)

This is a randomized, open label, multicenter trial to evaluate the safety, dosing, efficacy and biological activity of intraperitoneal IMNN-001 plus...

Active, not recruiting
Primary Peritoneal Cancer
Epithelial Ovarian Cancer
Biological: IMNN-001
Drug: Carboplatin

Phase 1, Phase 2

IMUNON
IMUNON

Birmingham, Alabama, United States and 20 other locations

A Study of Sovilnesib in Subjects With Ovarian Cancer

of sovilnesib at different dose levels to establish the Recommended Phase 2 Dose (RP2D) of sovilnesib in subjects with high grade serous ovarian...

Active, not recruiting
Fallopian Tube Cancer
Primary Peritoneal Carcinoma
Drug: Sovilnesib

Phase 1

Volastra Therapeutics

Birmingham, Alabama, United States and 12 other locations

A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. The purpose of this study is to assess the s...

Enrolling
Primary Peritoneal Cancer
Epithelial Ovarian Cancer
Drug: Mirvetuximab Soravtansine
Drug: Bevacizumab

Phase 2

AbbVie
AbbVie

Birmingham, Alabama, United States and 49 other locations

Locations recently updated

FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC (NAPISTAR1-01)

of TUB-040 and to find the best dose of TUB-040 in patients with ovarian cancer and Non Small Cell Lung Cancer. TUB-040 is...

Enrolling
Non-small Cell Lung Cancer
Ovarian Cancer
Drug: TUB-040

Phase 1, Phase 2

Tubulis

Birmingham, Alabama, United States and 14 other locations

A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

tirumotecan with or without bevacizumab live longer without the cancer getting worse than those who receive standard of care treatment....

Enrolling
Primary Peritoneal Cancer
Fallopian Tube Cancer
Drug: H2 receptor antagonist
Biological: Bevacizumab

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Birmingham, Alabama, United States and 99 other locations

Study of Chemotherapy With Pembrolizumab (MK-3475) Followed by Maintenance With Olaparib (MK-7339) for the First-Line Treatment of Women With BRCA Non-mutated Advanced Epithelial Ovarian Cancer (EOC) (MK-7339-001/KEYLYNK-001/ENGOT-ov43/GOG-3036)

and maintenance olaparib (MK-7339) in women with epithelial ovarian cancer (EOC), fallopian tube cancer, or primary perito...

Active, not recruiting
Peritoneal Neoplasms
Fallopian Tube Cancer
Biological: Bevacizumab
Drug: Placebo for olaparib

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Birmingham, Alabama, United States and 227 other locations

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