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in participants with human epidermal growth factor 2 (HER2)-expressing (immunohistochemistry \[IHC\] 3+/2+/1+) advanced high-grade epithelial ovarian...
Phase 3
Evanston, Illinois, United States and 207 other locations
This study is being done to answer the following question: What are the effects of a new drug or drugs on ovarian cancer? The pre-s...
Phase 2
Chicago, Illinois, United States and 5 other locations
and further the remissions and duration of remissions with standard ovarian cancer chemotherapy with carboplatin and paclitaxel. As...
Phase 2
Maywood, Illinois, United States
The goal of this clinical trial is to learn if the experimental antibody COM701 delays the progression of ovarian cancer in partici ...
Phase 1, Phase 2
Chicago, Illinois, United States and 27 other locations
followed by maintenance durvalumab and bevacizumab or durvalumab, bevacizumab and olaparib in patients with newly diagnosed advanced ovarian ...
Phase 3
Hinsdale, Illinois, United States and 213 other locations
of olaparib maintenance monotherapy in relapsed high grade serous ovarian cancer (HGSOC) patients (including patients with primary ...
Phase 3
Evanston, Illinois, United States and 126 other locations
Ovarian cancer (OC) is a lethal disease. The purpose of this study is to assess the safety, pharmacokinetics and efficacy of ABBV90 ...
Phase 1
Chicago, Illinois, United States and 21 other locations
the safety and efficacy of avutometinib (VS-6766) monotherapy and in combination with defactinib in subjects with recurrent Low-Grade Serous Ovarian...
Phase 2
Chicago, Illinois, United States and 46 other locations
efficacy with the combination of a next generation anti-CTLA-4 antibody, ONC-392, and anti-PD-1 antibody, pembrolizumab, in platinum resistant ovarian...
Phase 2
Hinsdale, Illinois, United States and 20 other locations
positive, recurrent platinum sensitive, high-grade epithelial ovarian, primary peritoneal, or fallopian tube cancer following 1 pri...
Phase 2
Chicago, Illinois, United States and 70 other locations
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