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The goal of this clinical trial is to compare participants with ovarian, fallopian tube or primary peritoneal cancer when treated w...
Phase 2
Detroit, Michigan, United States and 25 other locations
bevacizumab in women diagnosed with platinum-resistant/refractory ovarian cancer (includes fallopian tube cancer and prima...
Phase 3
Detroit, Michigan, United States and 22 other locations
followed by maintenance durvalumab and bevacizumab or durvalumab, bevacizumab and olaparib in patients with newly diagnosed advanced ovarian ...
Phase 3
Detroit, Michigan, United States and 213 other locations
clinical activity, pharmacokinetics (PK), and pharmacodynamics (PD) of ZN-c3 in combination with niraparib in subjects with platinum-resistant ovarian...
Phase 1, Phase 2
Detroit, Michigan, United States and 18 other locations
This study will assess the safety and efficacy of avutometinib (VS-6766) in combination with defactinib versus Investigator's choice of treatments (I...
Phase 3
Detroit, Michigan, United States and 21 other locations
positive, recurrent platinum sensitive, high-grade epithelial ovarian, primary peritoneal, or fallopian tube cancer following 1 pri...
Phase 2
Detroit, Michigan, United States and 70 other locations
This is a multi-center, open-label phase 1 dose escalation trial that uses a modified 3+3 design to identify a recommended phase 2 dose (RP2D) of AB-...
Phase 1
Detroit, Michigan, United States of America and 9 other locations
Olaparib Monotherapy in Patients with BRCA Mutated Ovarian Cancer following First Line Platinum Based Chemotherapy....
Phase 3
Detroit, Michigan, United States and 176 other locations
in combination with belinostat in subjects with Metastatic Breast Cancer, Metastatic Castration Resistant Prostate Cancer, and Meta ...
Phase 1
Ann Arbor, Michigan, United States
in combination with pembrolizumab versus protocol-specific Investigator's choice chemotherapy in patients with platinum-resistant epithelial ovarian...
Phase 3
Detroit, Michigan, United States and 131 other locations
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