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Find clinical trials for Ovarian Cancer in Durham, NC

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Related conditions:

Ovarian Epithelial Carcinoma
Cancer
Carcinoma
Endometrial Cancer
Fallopian Tube Cancer
Breast Cancer
Triple Negative Breast Cancer

Ovarian Cancer trials near Durham, NC, USA:

A Trial of Vigil for Participants With Ovarian Cancer (VITAL)

The goal of this clinical trial is to compare participants with ovarian, fallopian tube or primary peritoneal cancer when treated w...

Active, not recruiting
Ovarian Neoplasms
Ovarian Cancer
Biological: Vigil
Other: Placebo

Phase 2

Gradalis

Durham, North Carolina, United States and 25 other locations

followed by maintenance durvalumab and bevacizumab or durvalumab, bevacizumab and olaparib in patients with newly diagnosed advanced ovarian ...

Active, not recruiting
Advanced Ovarian Cancer
Drug: Durvalumab placebo
Drug: Bevacizumab

Phase 3

AstraZeneca
AstraZeneca

Durham, North Carolina, United States and 213 other locations

positive, recurrent platinum sensitive, high-grade epithelial ovarian, primary peritoneal, or fallopian tube cancer following 1 pri...

Active, not recruiting
Primary Peritoneal Cancer
High Grade Ovarian Cancer
Drug: Mirvetuximab soravtansine
Drug: Carboplatin

Phase 2

ImmunoGen
ImmunoGen

Durham, North Carolina, United States and 70 other locations

Olaparib Monotherapy in Patients with BRCA Mutated Ovarian Cancer following First Line Platinum Based Chemotherapy....

Active, not recruiting
Advanced Ovarian Cancer
FIGO Stage III-IV
Drug: Olaparib 300mg tablets

Phase 3

AstraZeneca
AstraZeneca

Durham, North Carolina, United States and 176 other locations

the safety and activity of oregovomab and niraparib as a combinatorial immune priming strategy in subjects with platinum sensitive recurrent ovarian...

Active, not recruiting
Recurrent Epithelial Ovarian Cancer
Recurrent Epithelial Cancer of Ovary
Drug: Niraparib
Biological: Oregovomab

Phase 2

CanariaBio

Durham, North Carolina, United States and 2 other locations

This is a Phase 1b open-label, multicenter study, evaluating the safety, tolerability, preliminary clinical activity, pharmacokinetics (PK), and phar...

Enrolling
Epithelial Ovarian Cancer
Peritoneal Cancer
Drug: Pegylated liposomal doxorubicin
Drug: Paclitaxel

Phase 1

K-Group Beta

Durham, North Carolina, United States and 22 other locations

within each cohort-specific supplement in participants with ovarian, fallopian tube, or primary peritoneal cancer. Cohort A (single ...

Enrolling
Ovarian Neoplasms
Drug: Niraparib
Drug: Paclitaxel

Phase 1, Phase 2

Tesaro
Tesaro

Durham, North Carolina, United States and 24 other locations

undergoing prospective ophthalmic evaluation with recurrent ovarian cancer (participants with either platinum-sensitive ovarian...

Not yet enrolling
Recurrent Ovarian Cancer
Folate Receptor-Alpha Positive
Drug: Prednisolone acetate ophthalmic suspension 1% eye drops
Drug: Lubricating Eye Drops

Phase 2

ImmunoGen
ImmunoGen

Durham, North Carolina, United States and 24 other locations

of Mirvetuximab Soravtansine in participants with platinum-sensitive ovarian, primary peritoneal or fallopian tube cancers with hig...

Active, not recruiting
Peritoneal Cancer
Fallopian Tube Cancer
Drug: Mirvetuximab soravtansine

Phase 2

ImmunoGen
ImmunoGen

Durham, North Carolina, United States and 77 other locations

outcome of ADP A2M4CD8 as monotherapy and in combination treatment with nivolumab in human leukocyte antigen (HLA) A2+ subjects with recurrent ovarian...

Enrolling
Ovarian Cancer
Genetic: Autologous genetically modified ADP-A2M4CD8 cells
Combination Product: Autologous genetically modified ADP-A2M4CD8 cells in combination with Nivolumab

Phase 2

Adaptimmune

Durham, North Carolina, United States and 27 other locations

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