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Find clinical trials for Ovarian Cancer in Durham, NC

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Related conditions:

Ovarian Epithelial Carcinoma
Cancer
Carcinoma
Endometrial Cancer
Fallopian Tube Cancer
Breast Cancer
Triple Negative Breast Cancer

Ovarian Cancer trials near Durham, NC, USA:

A Trial of Vigil for Participants With Ovarian Cancer (VITAL)

The goal of this clinical trial is to compare participants with ovarian, fallopian tube or primary peritoneal cancer when treated w...

Active, not recruiting
Ovarian Neoplasms
Ovarian Cancer
Other: Placebo
Biological: Vigil

Phase 2

Gradalis

Durham, North Carolina, United States and 25 other locations

followed by maintenance durvalumab and bevacizumab or durvalumab, bevacizumab and olaparib in patients with newly diagnosed advanced ovarian ...

Active, not recruiting
Advanced Ovarian Cancer
Drug: Bevacizumab
Drug: Durvalumab placebo

Phase 3

AstraZeneca
AstraZeneca

Durham, North Carolina, United States and 213 other locations

Olaparib Monotherapy in Patients with BRCA Mutated Ovarian Cancer following First Line Platinum Based Chemotherapy....

Active, not recruiting
Advanced Ovarian Cancer
FIGO Stage III-IV
Drug: Olaparib 300mg tablets

Phase 3

AstraZeneca
AstraZeneca

Durham, North Carolina, United States and 176 other locations

positive, recurrent platinum sensitive, high-grade epithelial ovarian, primary peritoneal, or fallopian tube cancer following 1 pri...

Active, not recruiting
Primary Peritoneal Cancer
High Grade Ovarian Cancer
Drug: Mirvetuximab soravtansine
Drug: Carboplatin

Phase 2

AbbVie
AbbVie

Durham, North Carolina, United States and 70 other locations

the safety and activity of oregovomab and niraparib as a combinatorial immune priming strategy in subjects with platinum sensitive recurrent ovarian...

Active, not recruiting
Recurrent Epithelial Ovarian Cancer
Recurrent Epithelial Cancer of Ovary
Biological: Oregovomab
Drug: Niraparib

Phase 2

CanariaBio

Durham, North Carolina, United States and 2 other locations

within each cohort-specific supplement in participants with ovarian, fallopian tube, or primary peritoneal cancer. Cohort A (single ...

Active, not recruiting
Ovarian Neoplasms
Drug: Paclitaxel
Drug: Niraparib

Phase 2

Tesaro
Tesaro

Durham, North Carolina, United States and 32 other locations

This is a Phase 1b open-label, multicenter study, evaluating the safety, tolerability, preliminary clinical activity, pharmacokinetics (PK), and phar...

Enrolling
Solid Tumor
Epithelial Ovarian Cancer
Drug: Pegylated liposomal doxorubicin
Drug: Paclitaxel

Phase 1

K-Group Beta

Durham, North Carolina, United States and 23 other locations

peripheral neuropathy (CIPN) in patients with recurrent ovarian and endometrial cancers, which are among the most lethal gynecologi...

Begins enrollment in 3 months
Ovarian Neoplasms
Endometrial Cancer, Endometrial Neoplasm
Drug: BMX-001
Drug: Paclitaxel (Taxol)

Phase 1, Phase 2

BioMimetix

Durham, North Carolina, United States

Locations recently updated

Patients will be registered prior to, during or at the completion of neoadjuvant chemotherapy (Paclitaxel 175 mg/m2 IV over 3 hours and Carboplatin A...

Enrolling
Stage IV Primary Peritoneal Cancer
Stage III Ovarian Cancer
Other: No treatment
Drug: Cisplatin

Phase 3

GOG Foundation

Durham, North Carolina, United States and 50 other locations

This study aims to assess efficacy of Niraparib (GSK3985771) as maintenance treatment in participants with Stage III or IV ovarian cancer...

Active, not recruiting
Ovarian Neoplasms
Drug: Placebo
Drug: Niraparib

Phase 3

Tesaro
Tesaro

Chapel Hill, North Carolina, United States and 196 other locations

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