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efficacy with the combination of a next generation anti-CTLA-4 antibody, ONC-392, and anti-PD-1 antibody, pembrolizumab, in platinum resistant ovarian...
Phase 2
Jacksonville, Florida, United States and 20 other locations
, which are pieces of a protein known as "folate receptor alpha" (FRalpha), a protein that is found in high levels on ovarian cancer...
Phase 1, Phase 2
Jacksonville, Florida, United States and 2 other locations
Ovarian cancer is a heterogeneous disease, characterized by complex molecular and genetic changes. The high expression of vascular ...
Phase 3
Jacksonville, Florida, United States and 179 other locations
This study aims to assess efficacy of Niraparib (GSK3985771) as maintenance treatment in participants with Stage III or IV ovarian cancer...
Phase 3
Jacksonville, Florida, United States and 199 other locations
following response to front-line treatment in newly diagnosed ovarian cancer patients. Response to treatment will be analyzed based...
Phase 3
Jacksonville, Florida, United States and 237 other locations
as maintenance therapy in participants with platinum-sensitive ovarian, primary peritoneal or fallopian tube cancers with high fola...
Phase 3
Jacksonville, Florida, United States and 244 other locations
The goal of this study is to test A2B694, an autologous logic-gated Tmod™ CAR T-cell product in subjects with solid tumors including colorec ...
Phase 1, Phase 2
Jacksonville, Florida, United States and 10 other locations
as PK and pharmacodynamics of XL309 (previously ISM3091) administered alone or in combination with olaparib in subjects with advanced solid tumors...
Phase 1
Jacksonville, Florida, United States and 15 other locations
-small-cell lung cancer (NSCLC), triple negative breast cancer (TNBC), ovarian cancer (OC), endometrial cancer...
Phase 1, Phase 2
Jacksonville, Florida, United States and 123 other locations
The primary purpose of this study is to assess the safety and tolerability of AB598 in participants with advanced malignancies.
Phase 1
Jacksonville, Florida, United States and 13 other locations
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