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and potential activity of a single intravenous (IV) dose of SynKIR-110 administered to subjects with mesothelin-expressing advanced ovarian ...
Phase 1
Westwood, Kansas, United States and 3 other locations
Patients will be registered prior to, during or at the completion of neoadjuvant chemotherapy (Paclitaxel 175 mg/m2 IV over 3 hours and Carboplatin A...
Phase 3
Kansas City, Kansas, United States and 50 other locations
This study will test the safety, including side effects, and determine the characteristics of a drug called PRO1184 in participants with solid tumors...
Phase 1, Phase 2
Westwood, Kansas, United States and 31 other locations
ecteribulin (MORAb-202) and compare it to Investigator's choice (IC) chemotherapy in female participants with platinum-resistant HGS ovarian....
Phase 2
Kansas City, Kansas, United States and 62 other locations
following response to front-line treatment in newly diagnosed ovarian cancer patients. Response to treatment will be analyzed based...
Phase 3
Westwood, Kansas, United States and 237 other locations
ultralow dose gemcitabine in participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma ba...
Phase 1, Phase 2
Kansas City, Missouri, United States and 66 other locations
The primary objective of this study is to evaluate progression-free survival (PFS) by blinded independent central review (BICR) in patients treated w...
Phase 3
Overland Park, Kansas, United States and 116 other locations
as maintenance therapy in participants with platinum-sensitive ovarian, primary peritoneal or fallopian tube cancers with high fola...
Phase 3
Westwood, Kansas, United States and 273 other locations
to find out whether it is safe for people who have solid tumors. It will study sigvotatug vedotin to find out what its side effects are. A s...
Phase 1
Westwood, Kansas, United States and 44 other locations
as PK and pharmacodynamics of XL309 (previously ISM3091) administered alone or in combination with olaparib in subjects with advanced solid tumors...
Phase 1
Kansas City, Missouri, United States and 11 other locations
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