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A) vs. mFOLFIRINOX plus placebo (Arm B) in 94 subjects with advanced pancreatic cancer, not amenable to curative treatment. Both ar...
Phase 2
Atlanta, Georgia, United States and 7 other locations
in first line treatment naïve subjects with Stage IV metastatic pancreatic carcinoma. The first part of study will focus on the treatment of ...
Phase 1, Phase 2
Newnan, Georgia, United States and 8 other locations
This phase II trial studies how well telotristat ethyl works in promoting weight stability in patients with pancreatic adenocarcinoma that h...
Phase 2
Atlanta, Georgia, United States and 2 other locations
A Phase 1/1b dose finding study to determine the OBD(s) and RP2D(s) of BMF-219, a covalent menin inhibitor small molecule, in subjects with KRAS muta...
Phase 1
Atlanta, Georgia, United States and 22 other locations
The purpose of this study is to confirm the recommended phase 2 dose (RP2D) of zolbetuximab in combination with Nab-P + GEM, determine overall surviv...
Phase 2
Newnan, Georgia, United States and 137 other locations
irinotecan work in treating patients with gastrointestinal cancers that have spread to other places in the body (metastatic) or cannot be re...
Phase 1, Phase 2
Atlanta, Georgia, United States and 2 other locations
This trial will study tisotumab vedotin to find out whether it is an effective treatment for certain solid tumors and what side effects (unwanted eff...
Phase 2
Atlanta, Georgia, United States and 60 other locations
This is a Phase I/II, open-label, multi-center, multi-national, dose escalation, single agent study to assess the safety, tolerability, PK, PD, immun...
Phase 2
Atlanta, Georgia, United States and 64 other locations
nivolumab or standard of care. It is being tested against advanced and/or metastatic solid tumors including gastric, gastroesophageal junction, pancreatic...
Phase 1, Phase 2
Atlanta, Georgia, United States and 18 other locations
This is an open-label, multicenter, global Phase 2 basket study of entrectinib (RXDX-101) for the treatment of patients with solid tumors that harbor...
Phase 2
Atlanta, Georgia, United States and 122 other locations
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