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and Pharmacodynamic Study of Minnelide™Capsules given daily for 21 days followed by 7 days off schedule in patients with Advanced Solid Tumors...
Phase 1
Birmingham, Alabama, United States and 6 other locations
* To evaluate the safety and tolerability of escalating doses of ERAS-007 in combination with other cancer therapies in study participants w...
Phase 1, Phase 2
Birmingham, Alabama, United States and 13 other locations
and clinical activity of ProAgio combined with gemcitabine and nab paclitaxel (G-nP) in previously untreated subjects with metastatic pancreatic...
Phase 1
Birmingham, Alabama, United States
This study is open to adults with advanced solid tumors whose previous cancer treatment was not successful. People can participate ...
Phase 1
Birmingham, Alabama, United States and 13 other locations
The purpose of this study is to find out whether the study drug, LY3537982, is safe and effective in cancer patients who have a specific gen...
Phase 1, Phase 2
Birmingham, Alabama, United States and 49 other locations
liposome injection in combination with other approved drugs used for cancer therapy, namely 5 fluorouracil/leucovorin (5FU/LV) plus oxalipla ...
Phase 3
Birmingham, Alabama, United States and 199 other locations
To evaluate the efficacy of naporafenib administered with trametinib in patients with rat sarcoma viral oncogene (RAS) Q61X solid tumors* To...
Phase 1
Birmingham, Alabama, United States and 30 other locations
This study is about TAK-500, given either alone or with pembrolizumab, in adults with select locally advanced or metastatic solid tumors.The...
Phase 1, Phase 2
Birmingham, Alabama, United States and 11 other locations
and clinical antitumor activity of XB002 administered IV q3w alone and in combination with nivolumab to subjects with advanced solid tumors....
Phase 1
Birmingham, Alabama, United States and 94 other locations
evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with advanced solid tumors...
Phase 1, Phase 2
Birmingham, Alabama, United States and 219 other locations
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