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* To evaluate the safety and tolerability of escalating doses of ERAS-007 in combination with other cancer therapies in study participants w...
Phase 1, Phase 2
Birmingham, Alabama, United States and 13 other locations
and Pharmacodynamic Study of Minnelide™Capsules given daily for 21 days followed by 7 days off schedule in patients with Advanced Solid Tumors...
Phase 1
Birmingham, Alabama, United States and 6 other locations
and clinical activity of ProAgio combined with gemcitabine and nab paclitaxel (G-nP) in previously untreated subjects with metastatic pancreatic...
Phase 1
Birmingham, Alabama, United States
The purpose of this study is to find out whether the study drug, LY3537982, is safe and effective in cancer patients who have a specific gen...
Phase 1, Phase 2
Birmingham, Alabama, United States and 49 other locations
to participants with locally advanced or metastatic solid tumors with certain KRAS mutations. LY4066434 will be given alone or in combinatio...
Phase 1
Birmingham, Alabama, United States and 44 other locations
To evaluate the efficacy of naporafenib administered with trametinib in patients with rat sarcoma viral oncogene (RAS) Q61X solid tumors* To...
Phase 1
Birmingham, Alabama, United States and 29 other locations
include tumors in the colon or rectum, the uterus and the cervix (lower part of the uterus), the bladder, and the biliary tract (includes g...
Phase 2
Birmingham, Alabama, United States and 50 other locations
and clinical antitumor activity of XB002 administered IV q3w alone and in combination with nivolumab to subjects with advanced solid tumors....
Phase 1
Birmingham, Alabama, United States and 94 other locations
evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with advanced solid tumors...
Phase 1, Phase 2
Birmingham, Alabama, United States and 219 other locations
This is a first-in-human Phase 1 clinical trial designed to investigate the safety, tolerability, pharmacokinetics, and biodistribution of \[225Ac\]-...
Phase 1
Birmingham, Alabama, United States and 7 other locations
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