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and clinical activity of ProAgio combined with gemcitabine and nab paclitaxel (G-nP) in previously untreated subjects with metastatic pancreatic...
Phase 1
Birmingham, Alabama, United States
A Phase I, Multicenter, Open-label, Dose-Escalation, Safety, Pharmacokinetic and Pharmacodynamic Study of Minnelide™Capsules given daily for 21 days...
Phase 1
Birmingham, Alabama, United States and 6 other locations
To evaluate the efficacy of naporafenib administered with trametinib in patients with rat sarcoma viral oncogene (RAS) Q61X solid tumors* To evaluate...
Phase 1
Birmingham, Alabama, United States and 28 other locations
liposome injection in combination with other approved drugs used for cancer therapy, namely 5 fluorouracil/leucovorin (5FU/LV) plus oxalipla ...
Phase 3
Birmingham, Alabama, United States and 199 other locations
This study is about TAK-500, given either alone or with pembrolizumab, in adults with select locally advanced or metastatic solid tumors.The aims of...
Phase 1, Phase 2
Birmingham, Alabama, United States and 11 other locations
This study is an open-label, international, multi-center, Phase 2 study in adult patients with recurrent, locally-advanced or metastatic solid tumors...
Phase 2
Birmingham, Alabama, United States and 41 other locations
This study will evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with adva...
Phase 1, Phase 2
Birmingham, Alabama, United States and 112 other locations
This is a Phase 1, open-label, multicenter, dose-escalation and expansion study evaluating the safety, tolerability, PK, pharmacodynamics, and clinic...
Phase 1
Birmingham, Alabama, United States and 91 other locations
* To evaluate the safety and tolerability of escalating doses of ERAS-007 in combination with other cancer therapies in study participants w...
Phase 1, Phase 2
Birmingham, Alabama, United States and 13 other locations
This is a first-in-human Phase 1 clinical trial designed to investigate the safety, tolerability, pharmacokinetics, and biodistribution of \[225Ac\]-...
Phase 1
Birmingham, Alabama, United States and 7 other locations
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