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Find clinical trials for Pancreatic Cancer in Charlotte, NC

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Related conditions:

Adenocarcinoma
Cancer
Carcinoma
Colorectal Cancer
Non-Small-Cell Lung Carcinoma
Lung Cancer
Squamous Cell Carcinoma of Head and Neck

Pancreatic Cancer trials near Charlotte, NC, USA:

A First-in-Human Study of SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors

This proposed Phase I clinical trial of SON-DP is an FIH, open-label, Phase Ia/Ib dose escalation and expansion study to evaluate the safety, tolerab...

Enrolling
Breast Cancer
Ovarian Cancer
Drug: SON-DP

Phase 1

Qurgen

Huntersville, North Carolina, United States and 4 other locations

The purpose of this study is to confirm the recommended phase 2 dose (RP2D) of zolbetuximab in combination with Nab-P + GEM, determine overall surviv...

Active, not recruiting
Metastatic Pancreatic Adenocarcinoma
Metastatic Pancreatic Cancer
Drug: nab-paclitaxel
Drug: gemcitabine

Phase 2

Astellas
Astellas

Charlotte, North Carolina, United States and 137 other locations

The study is a multi-center, open-label, randomized active controlled study of subjects with locally advanced pancreatic adenocarcinoma whic...

Enrolling
Locally Advanced Pancreatic Cancer
Device: RenovoCath
Drug: nab-paclitaxel

Phase 3

RenovoRx

Charlotte, North Carolina, United States and 38 other locations

This study is to evaluate the safety and tolerability of RMC-9805 in adults with KRAS G12D-mutant solid tumors.

Enrolling
Non-small Cell Lung Cancer (NSCLC)
Colorectal Cancer (CRC)
Drug: RMC-9805

Phase 1

Revolution Medicines
Revolution Medicines

Huntersville, North Carolina, United States and 6 other locations

(with enzalutamide-naïve metastatic castration-resistant prostate cancer) will be randomized to receive either NUV-868 monotherapy, enzaluta...

Enrolling
Cancer of Ovary
Castration Resistant Prostatic Cancer
Drug: Enzalutamide
Drug: NUV-868

Phase 1, Phase 2

Nuvation Bio

Huntersville, North Carolina, United States of America and 31 other locations

The purpose of this study is to further evaluate the efficacy and safety of niraparib in patients with locally advanced or metastatic solid tumors an...

Active, not recruiting
Esophageal Cancer
Urologic Cancer
Drug: Niraparib

Phase 2

Tempus AI
Tempus AI

Charlotte, North Carolina, United States and 79 other locations

This is an open-label, multicenter, global Phase 2 basket study of entrectinib (RXDX-101) for the treatment of patients with solid tumors that harbor...

Active, not recruiting
Breast Cancer
Papillary Thyroid Cancer
Drug: Entrectinib

Phase 2

Roche
Roche

Charlotte, North Carolina, United States and 122 other locations

This is a Phase 1, open-label, 2-part, multi-center study evaluating the safety, tolerability, PK, pharmacodynamics (PD), immunogenicity, and antitum...

Active, not recruiting
Gastric Cancer
Ovarian Cancer
Drug: CUE-102

Phase 1

Cue Biopharma

Huntersville, North Carolina, United States of America and 14 other locations

NUV-1511-01 is a first-in human, open- label, Phase 1/2 to evaluate the safety and efficacy of NUV-1511 in patients with advanced solid tumors. The P...

Enrolling
Metastatic Castration-resistant Prostate Cancer (mCRPC)
HER2-negative Breast Cancer
Drug: NUV-1511

Phase 1, Phase 2

Nuvation Bio

Huntersville, North Carolina, United States of America and 5 other locations

, metastatic castration-resistant prostate cancer (mCRPC), melanoma, pancreatic cancer, hepatocellular carcinoma (HCC), ov...

Enrolling
Epithelial Ovarian Cancer
Hepatocellular Cancer
Biological: lorigerlimab
Biological: vobramitamab duocarmazine

Phase 1

MacroGenics
MacroGenics

Huntersville, North Carolina, United States and 9 other locations

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