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This proposed Phase I clinical trial of SON-DP is an FIH, open-label, Phase Ia/Ib dose escalation and expansion study to evaluate the safety, tolerab...
Phase 1
Huntersville, North Carolina, United States and 4 other locations
The purpose of this study is to confirm the recommended phase 2 dose (RP2D) of zolbetuximab in combination with Nab-P + GEM, determine overall surviv...
Phase 2
Charlotte, North Carolina, United States and 137 other locations
The study is a multi-center, open-label, randomized active controlled study of subjects with locally advanced pancreatic adenocarcinoma whic...
Phase 3
Charlotte, North Carolina, United States and 38 other locations
This study is to evaluate the safety and tolerability of RMC-9805 as monotherapy and in combination with RMC-6236 in adults with KRAS G12D-mutant sol...
Phase 1
Huntersville, North Carolina, United States of America and 16 other locations
(with enzalutamide-naïve metastatic castration-resistant prostate cancer) will be randomized to receive either NUV-868 monotherapy, enzaluta...
Phase 1, Phase 2
Huntersville, North Carolina, United States of America and 30 other locations
The purpose of this study is to further evaluate the efficacy and safety of niraparib in patients with locally advanced or metastatic solid tumors an...
Phase 2
Charlotte, North Carolina, United States and 79 other locations
This is an open-label, multicenter, global Phase 2 basket study of entrectinib (RXDX-101) for the treatment of patients with solid tumors that harbor...
Phase 2
Charlotte, North Carolina, United States and 122 other locations
This is a Phase 1, open-label, 2-part, multi-center study evaluating the safety, tolerability, PK, pharmacodynamics (PD), immunogenicity, and antitum...
Phase 1
Huntersville, North Carolina, United States of America and 14 other locations
NUV-1511-01 is a first-in human, open- label, Phase 1/2 to evaluate the safety and efficacy of NUV-1511 in patients with advanced solid tumors. The P...
Phase 1, Phase 2
Huntersville, North Carolina, United States of America and 5 other locations
, metastatic castration-resistant prostate cancer (mCRPC), melanoma, pancreatic cancer, hepatocellular carcinoma (HCC), ov...
Phase 1
Huntersville, North Carolina, United States and 9 other locations
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