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Find clinical trials for Pancreatic Cancer in Jacksonville, FL

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Pancreatic Cancer trials near Jacksonville, FL, USA:

Locations recently updated

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

Pancreatic cancer is difficult to diagnose early. By the time people have been diagnosed, the cancer has usually spread to ...

Enrolling
Metastatic Pancreatic Adenocarcinoma
Metastatic Pancreatic Cancer
Drug: Oxaliplatin
Drug: Leucovorin

Phase 3

Astellas
Astellas

Jacksonville, Florida, United States and 103 other locations

study will assess the safety and efficacy of VS-7375 alone and in combination with cetuximab in patients with metastatic KRAS G12D - mutated Pancreatic...

Enrolling
Pancreatic Ductal Adenocarcinoma (PDAC)
G12D Mutated KRAS
Drug: VS-7375
Drug: cetuximab (or panitumumab if α-gal IgE+ or cetuximab reaction)

Phase 2

Verastem

Jacksonville, Florida, United States and 37 other locations

This phase II study evaluates how well pemigatinib works for the treatment of adult patients with pancreatic cancer that has spread...

Enrolling
Metastatic Pancreatic Carcinoma
Stage IV Pancreatic Cancer AJCC v8
Drug: Pemigatinib
Procedure: Bone Scan

Phase 2

Sameek Roychowdhury

Jacksonville, Florida, United States and 108 other locations

TNG462-C102 is a Phase 1/2, open-label, multicenter study designed to determine the safety, tolerability, PK, PD, and preliminary antineoplastic acti...

Enrolling
Pancreatic Cancer Metastatic
PDAC - Pancreatic Ductal Adenocarcinoma
Drug: TNG462
Drug: gemcitabine/nab-paclitaxel

Phase 1, Phase 2

Tango Therapeutics
Tango Therapeutics

Jacksonville, Florida, United States and 17 other locations

The purpose of this study is to evaluate the efficacy of combination therapy with two investigational RAS(ON) inhibitors (daraxonrasib and zoldonrasi...

Enrolling
Pancreatic Cancer Metastatic
Pancreatic Adenocarcinoma Metastatic
Drug: nab-paclitaxel
Drug: zoldonrasib

Phase 3

Revolution Medicines
Revolution Medicines

Jacksonville, Florida, United States and 4 other locations

The purpose of this study is to evaluate the efficacy of an investigational RAS(ON) inhibitor administered in combination with chemotherapy compared...

Enrolling
Pancreatic Cancer Metastatic
Pancreatic Adenocarcinoma Metastatic
Drug: Gemcitabine (GEM)
Drug: Nab-paclitaxel

Phase 3

Revolution Medicines
Revolution Medicines

Jacksonville, Florida, United States and 19 other locations

The purpose of this study is to evaluate the safety and efficacy of an investigational RAS(ON) inhibitor administered as monotherapy or in combinatio...

Enrolling
Pancreatic Cancer Metastatic
Pancreatic Adenocarcinoma Metastatic
Drug: daraxonrasib
Drug: nab-paclitaxel

Phase 3

Revolution Medicines
Revolution Medicines

Jacksonville, Florida, United States and 81 other locations

Cisplatin, And Gemcitabine (GCN) Combined with Tumor Treatment Fields (TTF) and G+TTF maintenance therapy in patients with metastatic pancreatic...

Active, not recruiting
Metastatic Pancreatic Cancer
Pancreatic Adenocarcinoma
Combination Product: Modified GCN+TTF treatment

Phase 1, Phase 2

Mayo Clinic
Mayo Clinic

Jacksonville, Florida, United States

The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard of care (SOC) observation only.

Enrolling
Resected Pancreatic Adenocarcinoma
PDAC - Pancreatic Ductal Adenocarcinoma
Drug: daraxonrasib

Phase 3

Revolution Medicines
Revolution Medicines

Jacksonville, Florida, United States and 85 other locations

The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard(s) of care (SOC) treatment.

Active, not recruiting
PDAC - Pancreatic Ductal Adenocarcinoma
Pancreatic Cancer
Drug: 5-fluorouracil
Drug: leucovorin

Phase 3

Revolution Medicines
Revolution Medicines

Jacksonville, Florida, United States and 59 other locations

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